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ESMO-MCBS Scorecards

ESMO MCBS  1000x150

The searchable portal provides a centralised location of cancer medicines that have been scored and published by ESMO.

The ESMO-MCBS Scorecards

The ESMO-MCBS Scorecards allows you to filter either by Agent, Tumour or Score giving priority to different criteria such as Agent and Tumour Type and Tumour sub-type and Tumour sub-group in the Curative or Non-curative setting. This content will be updated regularly and communicated to ESMO Members.

Tested Agent(s) Combined Agent(s) Control Arm Treatment Setting Tumour Type Tumour Sub-type Tumour Sub-group Tumour Stage Score Ref. Scorecard
Atezolizumab - Platinum-based chemotherapy First-line treatment of patients with high PD-L1 expression Thoracic Malignancies Non-small-cell Lung Cancer - Metastatic
5
Nivolumab - Single arm (Phase I/II) Metastatic with progression after platinum-based ChT and at least one other line of therapy regardless of PD-L1 status Thoracic Malignancies Small-cell Lung Cancer - Metastatic
1
Pembrolizumab - Single arm (Phase II) Metastatic with disease progression on or after platinum-based ChT and at least one other prior line of therapy Thoracic Malignancies Small-cell Lung Cancer - Metastatic
1
Encorafenib Binimetinib Vemurafenib Advanced unresectable or metastatic melanoma with a BRAF V600E or V600K mutation Skin Cancers Melanoma BRAF V600E or V600K Advanced unresectable or metastatic
4
Pembrolizumab ChT Placebo plus ChT 1st line treatment Breast Cancer Breast Cancer Triple-negative, PD-L1 (CPS >10) Locally recurrent inoperable or metastatic
3
Nivolumab - Single arm (Phase II) Treatment after failure of prior platinum-containing therapy Genitourinary Cancers Urothelial Carcinoma - Locally advanced unresectable or metastatic
1
Osimertinib 3 years - Placebo Adjuvant therapy after tumour resection Thoracic Malignancies Non-small-cell Lung Cancer EGFR exon 19 deletions or exon 21 (L858R) mutation Adjuvant
A
Margetuximab ChT Trastuzumab plus ChT Treatment of adult patients who have received two or more prior anti-HER2 regimes, at least one of which was for metastatic disease Breast Cancer Breast Cancer HER2+ Metastatic
2
Trastuzumab Deruxtecan - Either irinitecan or paclitaxel (Phase II) Previously treated on at least two prior regimes Gastrointestinal Cancers Gastric or gastro-oesophageal junction adenocarcinoma HER2+ Locally advanced or metastatic
4

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