ESMO Newshttps://www.esmo.org/The latest news from ESMOen-GBnoreply@esmo.org242, 30 Aug 2025 08:08:95 +00:00242, 30 Aug 2025 08:08:95 +00:00 FDA Grants Accelerated Approval to Zongertinib for Non-squamous NSCLC with HER2 Tyrosine Kinase Domain Activating Mutations https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the Beamion LUNG-1 study</p>noreply@esmo.orgbb0dc137-253d-4b77-929b-1beb77fa87e2Fri, 29 Aug 2025 08:08:00 +00:00 Early-Stage and Locally Advanced NSCLC: ESMO Clinical Practice Guideline https://www.esmo.orgnull<p>This updated ESMO CPG provides diagnosis, staging, risk assessment, treatment and follow-up recommendations. It introduces new systemic treatments and innovative strategies, offering physicians practicing thoracic oncology advanced therapeutic options to improve outcomes and personalise care.</p>noreply@esmo.org8d7a31cc-4316-426c-9a9b-fe53dece6133Thu, 28 Aug 2025 08:08:00 +00:00 Superior EFS and OS in Patients with Nonmetastatic Osteosarcoma and Unfavourable Prognosis when Adjuvant Mifamurtide is Combined with High-Dose Ifosfamide https://www.esmo.orgnull<p>Findings from the ISG/OS-2 and GEIS-33 studies</p>noreply@esmo.org71f4b205-e613-44f8-86f1-e6b1afc68c9eThu, 28 Aug 2025 08:08:00 +00:00 Molecular Analysis for Precision Oncology Congress 2025, Paris, France, 15-16 September https://www.esmo.orgnull<p>The Molecular Analysis for Precision Oncology Congress 2025 (MAP) will bring together leading experts to explore the latest advances in cancer research, with a focus on deepening the understanding of disease mechanism and enhancing strategies for prevention and interception</p>noreply@esmo.org8b521c78-d705-426c-af80-d640aafdba56Wed, 27 Aug 2025 07:08:00 +00:00 Combining Enzalutamide with Radium-223 Significantly Improves rPFS as First-Line Therapy for Patients with mCRPC https://www.esmo.orgnull<p>Findings from the PEACE-3 study</p>noreply@esmo.orgf7879b8d-5c1c-4259-8f0d-efe16d428097Wed, 27 Aug 2025 07:08:00 +00:00 AI and remote monitoring are shaping a new patient journey in oncology https://www.esmo.orgnull<p>Real world experience suggests that the integration of digital tools into cancer care may close current gaps in patient outcomes reporting</p>noreply@esmo.org34da15a5-c125-47bd-b755-aa2474d72593Tue, 26 Aug 2025 22:08:00 +00:00 In Memory of Håkan Mellstedt: Former ESMO President https://www.esmo.orgnull<p>It is with deep sadness that ESMO has learnt of the passing of Professor Håkan Mellstedt, who died recently at the age of 82</p>noreply@esmo.org7dc6e2e0-2732-4ef0-852d-5cd9c71daf1bTue, 26 Aug 2025 12:08:00 +00:00 EMA Recommends Granting a Conditional Marketing Authorisation for Obecabtagene Autoleucel https://www.esmo.orgnull<p>It is intended for the treatment of adults from 26 years of age with relapsed or refractory B cell precursor ALL</p>noreply@esmo.orgb883a1ba-0478-438c-b5ad-b855cbfc0d09Tue, 26 Aug 2025 07:08:00 +00:00 Additional 5 Years of AI Treatment Reduces Distant Recurrence Rates Among Postmenopausal Women Already Treated with at Least 5 Years of Endocrine Therapy https://www.esmo.orgnull<p>Findings from a meta-analysis performed by the Early Breast Cancer Trialists' Collaborative Group</p>noreply@esmo.orgaae366ec-0676-4745-8c5a-f3417ecafa3eMon, 25 Aug 2025 07:08:00 +00:00 FDA Grants Accelerated Approval to Dordaviprone for Diffuse Midline Glioma https://www.esmo.orgnull<p>Evidence for efficacy is based on results from the ONC006, ONC013, ONC014, ONC016 and ONC018 studies</p>noreply@esmo.orga619a127-a1d6-4f54-96e8-4bdf3e567f21Fri, 22 Aug 2025 07:08:00 +00:00 Clinical Benefit and Genomic Features Associations Observed with Pembrolizumab Plus Axitinib in Patients with Advanced Clear Cell RCC https://www.esmo.orgnull<p>Findings from the KEYNOTE-426 study</p>noreply@esmo.org36cbe128-7def-4a17-9bd8-c253a9dfb8aaThu, 21 Aug 2025 07:08:00 +00:00 Adagrasib Improves PFS Over Docetaxel in Patients with Previously Treated KRASG12C-mutated NSCLC https://www.esmo.orgnull<p>Findings from the KRYSTAL-12 study</p>noreply@esmo.org8c65622a-b33b-4f13-8f22-12eb2c009b82Wed, 20 Aug 2025 07:08:00 +00:00 No Survival Benefit from Adding Adjuvant Chemotherapy to Endocrine Therapy in Older Women with a Genomic Grade Index High-Risk ER-positive, HER2-negative Breast Cancer https://www.esmo.orgnull<p>Findings from the ASTER 70s study</p>noreply@esmo.org2d825557-d2eb-4f7f-acb9-251237054d65Tue, 19 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Belantamab Mafodotin https://www.esmo.orgnull<p>It is intended for the treatment of patients with relapsed or refractory multiple myeloma</p>noreply@esmo.org965f5a4a-9a84-430c-bc6f-e40ca62558f5Mon, 18 Aug 2025 07:08:00 +00:00 ESMO Joins the European Health Alliance on Alcohol (EHAA) Seeking to Reduce Preventable Cancer Cases Linked to Alcohol Use https://www.esmo.orgnull<p>With alcohol consumption increasing the risk of developing at least 7 types of cancer, ESMO considers it crucial that robust policy action - at all political levels - is taken to effectively address the impact of alcohol-related harm on human health, thus enhancing cancer prevention</p>noreply@esmo.org796a42df-36fd-4a93-9ee2-41fa00b14ba2Thu, 14 Aug 2025 09:08:00 +00:00 CLDN18.2-Specific CAR T-Cell Therapy Prolongs PFS in Patients with Previously Treated Advanced Gastric or Gastro-oesophageal Junction Cancer https://www.esmo.orgnull<p>Findings from the CT041-ST-01 study</p>noreply@esmo.orgbebed821-c39b-48c2-bce8-7c5c96e4a8dbThu, 14 Aug 2025 07:08:00 +00:00 FDA Approves Tafasitamab-cxix for Relapsed or Refractory Follicular Lymphoma https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the inMIND study</p>noreply@esmo.org5e4115df-3e7b-4e40-bf32-d67663bd25ceThu, 14 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Vorasidenib https://www.esmo.orgnull<p>It is intended for the treatment of adults and adolescents with low grade astrocytoma or oligodendroglioma with an <em>IDH1</em> R132 or <em>IDH2</em> R172 mutation</p>noreply@esmo.org33595183-53c1-46d7-8d11-8efbe77ad103Wed, 13 Aug 2025 07:08:00 +00:00 Postoperative Radioiodine Can Be Avoided in Patients with Low-Risk Differentiated Thyroid Cancer https://www.esmo.orgnull<p>Findings from the IoN&nbsp;study</p>noreply@esmo.orgf44a7b22-946b-4057-90c0-b17c5d006568Tue, 12 Aug 2025 07:08:00 +00:00 ESMO Recommendations on Cancer Care Reflected in UN ECOSOC Ministerial Declaration on Sustainable Development https://www.esmo.orgnull<p>At the conclusion of the 2025 High-Level Political Forum (HLPF) on Sustainable Development, UN Member States adopted a Ministerial Declaration reaffirming commitment to universal health coverage (UHC), resilient health systems, and tackling non-communicable diseases (NCDs) like cancer</p>noreply@esmo.org1bac8e44-2826-4e2e-941a-7cda78fe8ffaMon, 11 Aug 2025 07:08:00 +00:00 ESMO Newshttps://www.esmo.org/The latest news from ESMOen-GBnoreply@esmo.org242, 30 Aug 2025 08:08:55 +00:00242, 30 Aug 2025 08:08:55 +00:00 FDA Grants Accelerated Approval to Zongertinib for Non-squamous NSCLC with HER2 Tyrosine Kinase Domain Activating Mutations https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the Beamion LUNG-1 study</p>noreply@esmo.orgbb0dc137-253d-4b77-929b-1beb77fa87e2Fri, 29 Aug 2025 08:08:00 +00:00 Early-Stage and Locally Advanced NSCLC: ESMO Clinical Practice Guideline https://www.esmo.orgnull<p>This updated ESMO CPG provides diagnosis, staging, risk assessment, treatment and follow-up recommendations. It introduces new systemic treatments and innovative strategies, offering physicians practicing thoracic oncology advanced therapeutic options to improve outcomes and personalise care.</p>noreply@esmo.org8d7a31cc-4316-426c-9a9b-fe53dece6133Thu, 28 Aug 2025 08:08:00 +00:00 Superior EFS and OS in Patients with Nonmetastatic Osteosarcoma and Unfavourable Prognosis when Adjuvant Mifamurtide is Combined with High-Dose Ifosfamide https://www.esmo.orgnull<p>Findings from the ISG/OS-2 and GEIS-33 studies</p>noreply@esmo.org71f4b205-e613-44f8-86f1-e6b1afc68c9eThu, 28 Aug 2025 08:08:00 +00:00 Molecular Analysis for Precision Oncology Congress 2025, Paris, France, 15-16 September https://www.esmo.orgnull<p>The Molecular Analysis for Precision Oncology Congress 2025 (MAP) will bring together leading experts to explore the latest advances in cancer research, with a focus on deepening the understanding of disease mechanism and enhancing strategies for prevention and interception</p>noreply@esmo.org8b521c78-d705-426c-af80-d640aafdba56Wed, 27 Aug 2025 07:08:00 +00:00 Combining Enzalutamide with Radium-223 Significantly Improves rPFS as First-Line Therapy for Patients with mCRPC https://www.esmo.orgnull<p>Findings from the PEACE-3 study</p>noreply@esmo.orgf7879b8d-5c1c-4259-8f0d-efe16d428097Wed, 27 Aug 2025 07:08:00 +00:00 AI and remote monitoring are shaping a new patient journey in oncology https://www.esmo.orgnull<p>Real world experience suggests that the integration of digital tools into cancer care may close current gaps in patient outcomes reporting</p>noreply@esmo.org34da15a5-c125-47bd-b755-aa2474d72593Tue, 26 Aug 2025 22:08:00 +00:00 In Memory of Håkan Mellstedt: Former ESMO President https://www.esmo.orgnull<p>It is with deep sadness that ESMO has learnt of the passing of Professor Håkan Mellstedt, who died recently at the age of 82</p>noreply@esmo.org7dc6e2e0-2732-4ef0-852d-5cd9c71daf1bTue, 26 Aug 2025 12:08:00 +00:00 EMA Recommends Granting a Conditional Marketing Authorisation for Obecabtagene Autoleucel https://www.esmo.orgnull<p>It is intended for the treatment of adults from 26 years of age with relapsed or refractory B cell precursor ALL</p>noreply@esmo.orgb883a1ba-0478-438c-b5ad-b855cbfc0d09Tue, 26 Aug 2025 07:08:00 +00:00 Additional 5 Years of AI Treatment Reduces Distant Recurrence Rates Among Postmenopausal Women Already Treated with at Least 5 Years of Endocrine Therapy https://www.esmo.orgnull<p>Findings from a meta-analysis performed by the Early Breast Cancer Trialists' Collaborative Group</p>noreply@esmo.orgaae366ec-0676-4745-8c5a-f3417ecafa3eMon, 25 Aug 2025 07:08:00 +00:00 FDA Grants Accelerated Approval to Dordaviprone for Diffuse Midline Glioma https://www.esmo.orgnull<p>Evidence for efficacy is based on results from the ONC006, ONC013, ONC014, ONC016 and ONC018 studies</p>noreply@esmo.orga619a127-a1d6-4f54-96e8-4bdf3e567f21Fri, 22 Aug 2025 07:08:00 +00:00 Clinical Benefit and Genomic Features Associations Observed with Pembrolizumab Plus Axitinib in Patients with Advanced Clear Cell RCC https://www.esmo.orgnull<p>Findings from the KEYNOTE-426 study</p>noreply@esmo.org36cbe128-7def-4a17-9bd8-c253a9dfb8aaThu, 21 Aug 2025 07:08:00 +00:00 Adagrasib Improves PFS Over Docetaxel in Patients with Previously Treated KRASG12C-mutated NSCLC https://www.esmo.orgnull<p>Findings from the KRYSTAL-12 study</p>noreply@esmo.org8c65622a-b33b-4f13-8f22-12eb2c009b82Wed, 20 Aug 2025 07:08:00 +00:00 No Survival Benefit from Adding Adjuvant Chemotherapy to Endocrine Therapy in Older Women with a Genomic Grade Index High-Risk ER-positive, HER2-negative Breast Cancer https://www.esmo.orgnull<p>Findings from the ASTER 70s study</p>noreply@esmo.org2d825557-d2eb-4f7f-acb9-251237054d65Tue, 19 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Belantamab Mafodotin https://www.esmo.orgnull<p>It is intended for the treatment of patients with relapsed or refractory multiple myeloma</p>noreply@esmo.org965f5a4a-9a84-430c-bc6f-e40ca62558f5Mon, 18 Aug 2025 07:08:00 +00:00 ESMO Joins the European Health Alliance on Alcohol (EHAA) Seeking to Reduce Preventable Cancer Cases Linked to Alcohol Use https://www.esmo.orgnull<p>With alcohol consumption increasing the risk of developing at least 7 types of cancer, ESMO considers it crucial that robust policy action - at all political levels - is taken to effectively address the impact of alcohol-related harm on human health, thus enhancing cancer prevention</p>noreply@esmo.org796a42df-36fd-4a93-9ee2-41fa00b14ba2Thu, 14 Aug 2025 09:08:00 +00:00 CLDN18.2-Specific CAR T-Cell Therapy Prolongs PFS in Patients with Previously Treated Advanced Gastric or Gastro-oesophageal Junction Cancer https://www.esmo.orgnull<p>Findings from the CT041-ST-01 study</p>noreply@esmo.orgbebed821-c39b-48c2-bce8-7c5c96e4a8dbThu, 14 Aug 2025 07:08:00 +00:00 FDA Approves Tafasitamab-cxix for Relapsed or Refractory Follicular Lymphoma https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the inMIND study</p>noreply@esmo.org5e4115df-3e7b-4e40-bf32-d67663bd25ceThu, 14 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Vorasidenib https://www.esmo.orgnull<p>It is intended for the treatment of adults and adolescents with low grade astrocytoma or oligodendroglioma with an <em>IDH1</em> R132 or <em>IDH2</em> R172 mutation</p>noreply@esmo.org33595183-53c1-46d7-8d11-8efbe77ad103Wed, 13 Aug 2025 07:08:00 +00:00 Postoperative Radioiodine Can Be Avoided in Patients with Low-Risk Differentiated Thyroid Cancer https://www.esmo.orgnull<p>Findings from the IoN&nbsp;study</p>noreply@esmo.orgf44a7b22-946b-4057-90c0-b17c5d006568Tue, 12 Aug 2025 07:08:00 +00:00 ESMO Recommendations on Cancer Care Reflected in UN ECOSOC Ministerial Declaration on Sustainable Development https://www.esmo.orgnull<p>At the conclusion of the 2025 High-Level Political Forum (HLPF) on Sustainable Development, UN Member States adopted a Ministerial Declaration reaffirming commitment to universal health coverage (UHC), resilient health systems, and tackling non-communicable diseases (NCDs) like cancer</p>noreply@esmo.org1bac8e44-2826-4e2e-941a-7cda78fe8ffaMon, 11 Aug 2025 07:08:00 +00:00 ESMO Newshttps://www.esmo.org/The latest news from ESMOen-GBnoreply@esmo.org242, 30 Aug 2025 08:08:92 +00:00242, 30 Aug 2025 08:08:92 +00:00 FDA Grants Accelerated Approval to Zongertinib for Non-squamous NSCLC with HER2 Tyrosine Kinase Domain Activating Mutations https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the Beamion LUNG-1 study</p>noreply@esmo.orgbb0dc137-253d-4b77-929b-1beb77fa87e2Fri, 29 Aug 2025 08:08:00 +00:00 Early-Stage and Locally Advanced NSCLC: ESMO Clinical Practice Guideline https://www.esmo.orgnull<p>This updated ESMO CPG provides diagnosis, staging, risk assessment, treatment and follow-up recommendations. It introduces new systemic treatments and innovative strategies, offering physicians practicing thoracic oncology advanced therapeutic options to improve outcomes and personalise care.</p>noreply@esmo.org8d7a31cc-4316-426c-9a9b-fe53dece6133Thu, 28 Aug 2025 08:08:00 +00:00 Superior EFS and OS in Patients with Nonmetastatic Osteosarcoma and Unfavourable Prognosis when Adjuvant Mifamurtide is Combined with High-Dose Ifosfamide https://www.esmo.orgnull<p>Findings from the ISG/OS-2 and GEIS-33 studies</p>noreply@esmo.org71f4b205-e613-44f8-86f1-e6b1afc68c9eThu, 28 Aug 2025 08:08:00 +00:00 Molecular Analysis for Precision Oncology Congress 2025, Paris, France, 15-16 September https://www.esmo.orgnull<p>The Molecular Analysis for Precision Oncology Congress 2025 (MAP) will bring together leading experts to explore the latest advances in cancer research, with a focus on deepening the understanding of disease mechanism and enhancing strategies for prevention and interception</p>noreply@esmo.org8b521c78-d705-426c-af80-d640aafdba56Wed, 27 Aug 2025 07:08:00 +00:00 Combining Enzalutamide with Radium-223 Significantly Improves rPFS as First-Line Therapy for Patients with mCRPC https://www.esmo.orgnull<p>Findings from the PEACE-3 study</p>noreply@esmo.orgf7879b8d-5c1c-4259-8f0d-efe16d428097Wed, 27 Aug 2025 07:08:00 +00:00 AI and remote monitoring are shaping a new patient journey in oncology https://www.esmo.orgnull<p>Real world experience suggests that the integration of digital tools into cancer care may close current gaps in patient outcomes reporting</p>noreply@esmo.org34da15a5-c125-47bd-b755-aa2474d72593Tue, 26 Aug 2025 22:08:00 +00:00 In Memory of Håkan Mellstedt: Former ESMO President https://www.esmo.orgnull<p>It is with deep sadness that ESMO has learnt of the passing of Professor Håkan Mellstedt, who died recently at the age of 82</p>noreply@esmo.org7dc6e2e0-2732-4ef0-852d-5cd9c71daf1bTue, 26 Aug 2025 12:08:00 +00:00 EMA Recommends Granting a Conditional Marketing Authorisation for Obecabtagene Autoleucel https://www.esmo.orgnull<p>It is intended for the treatment of adults from 26 years of age with relapsed or refractory B cell precursor ALL</p>noreply@esmo.orgb883a1ba-0478-438c-b5ad-b855cbfc0d09Tue, 26 Aug 2025 07:08:00 +00:00 Additional 5 Years of AI Treatment Reduces Distant Recurrence Rates Among Postmenopausal Women Already Treated with at Least 5 Years of Endocrine Therapy https://www.esmo.orgnull<p>Findings from a meta-analysis performed by the Early Breast Cancer Trialists' Collaborative Group</p>noreply@esmo.orgaae366ec-0676-4745-8c5a-f3417ecafa3eMon, 25 Aug 2025 07:08:00 +00:00 FDA Grants Accelerated Approval to Dordaviprone for Diffuse Midline Glioma https://www.esmo.orgnull<p>Evidence for efficacy is based on results from the ONC006, ONC013, ONC014, ONC016 and ONC018 studies</p>noreply@esmo.orga619a127-a1d6-4f54-96e8-4bdf3e567f21Fri, 22 Aug 2025 07:08:00 +00:00 Clinical Benefit and Genomic Features Associations Observed with Pembrolizumab Plus Axitinib in Patients with Advanced Clear Cell RCC https://www.esmo.orgnull<p>Findings from the KEYNOTE-426 study</p>noreply@esmo.org36cbe128-7def-4a17-9bd8-c253a9dfb8aaThu, 21 Aug 2025 07:08:00 +00:00 Adagrasib Improves PFS Over Docetaxel in Patients with Previously Treated KRASG12C-mutated NSCLC https://www.esmo.orgnull<p>Findings from the KRYSTAL-12 study</p>noreply@esmo.org8c65622a-b33b-4f13-8f22-12eb2c009b82Wed, 20 Aug 2025 07:08:00 +00:00 No Survival Benefit from Adding Adjuvant Chemotherapy to Endocrine Therapy in Older Women with a Genomic Grade Index High-Risk ER-positive, HER2-negative Breast Cancer https://www.esmo.orgnull<p>Findings from the ASTER 70s study</p>noreply@esmo.org2d825557-d2eb-4f7f-acb9-251237054d65Tue, 19 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Belantamab Mafodotin https://www.esmo.orgnull<p>It is intended for the treatment of patients with relapsed or refractory multiple myeloma</p>noreply@esmo.org965f5a4a-9a84-430c-bc6f-e40ca62558f5Mon, 18 Aug 2025 07:08:00 +00:00 ESMO Joins the European Health Alliance on Alcohol (EHAA) Seeking to Reduce Preventable Cancer Cases Linked to Alcohol Use https://www.esmo.orgnull<p>With alcohol consumption increasing the risk of developing at least 7 types of cancer, ESMO considers it crucial that robust policy action - at all political levels - is taken to effectively address the impact of alcohol-related harm on human health, thus enhancing cancer prevention</p>noreply@esmo.org796a42df-36fd-4a93-9ee2-41fa00b14ba2Thu, 14 Aug 2025 09:08:00 +00:00 CLDN18.2-Specific CAR T-Cell Therapy Prolongs PFS in Patients with Previously Treated Advanced Gastric or Gastro-oesophageal Junction Cancer https://www.esmo.orgnull<p>Findings from the CT041-ST-01 study</p>noreply@esmo.orgbebed821-c39b-48c2-bce8-7c5c96e4a8dbThu, 14 Aug 2025 07:08:00 +00:00 FDA Approves Tafasitamab-cxix for Relapsed or Refractory Follicular Lymphoma https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the inMIND study</p>noreply@esmo.org5e4115df-3e7b-4e40-bf32-d67663bd25ceThu, 14 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Vorasidenib https://www.esmo.orgnull<p>It is intended for the treatment of adults and adolescents with low grade astrocytoma or oligodendroglioma with an <em>IDH1</em> R132 or <em>IDH2</em> R172 mutation</p>noreply@esmo.org33595183-53c1-46d7-8d11-8efbe77ad103Wed, 13 Aug 2025 07:08:00 +00:00 Postoperative Radioiodine Can Be Avoided in Patients with Low-Risk Differentiated Thyroid Cancer https://www.esmo.orgnull<p>Findings from the IoN&nbsp;study</p>noreply@esmo.orgf44a7b22-946b-4057-90c0-b17c5d006568Tue, 12 Aug 2025 07:08:00 +00:00 ESMO Recommendations on Cancer Care Reflected in UN ECOSOC Ministerial Declaration on Sustainable Development https://www.esmo.orgnull<p>At the conclusion of the 2025 High-Level Political Forum (HLPF) on Sustainable Development, UN Member States adopted a Ministerial Declaration reaffirming commitment to universal health coverage (UHC), resilient health systems, and tackling non-communicable diseases (NCDs) like cancer</p>noreply@esmo.org1bac8e44-2826-4e2e-941a-7cda78fe8ffaMon, 11 Aug 2025 07:08:00 +00:00 ESMO Newshttps://www.esmo.org/The latest news from ESMOen-GBnoreply@esmo.org242, 30 Aug 2025 08:08:55 +00:00242, 30 Aug 2025 08:08:55 +00:00 FDA Grants Accelerated Approval to Zongertinib for Non-squamous NSCLC with HER2 Tyrosine Kinase Domain Activating Mutations https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the Beamion LUNG-1 study</p>noreply@esmo.orgbb0dc137-253d-4b77-929b-1beb77fa87e2Fri, 29 Aug 2025 08:08:00 +00:00 Early-Stage and Locally Advanced NSCLC: ESMO Clinical Practice Guideline https://www.esmo.orgnull<p>This updated ESMO CPG provides diagnosis, staging, risk assessment, treatment and follow-up recommendations. It introduces new systemic treatments and innovative strategies, offering physicians practicing thoracic oncology advanced therapeutic options to improve outcomes and personalise care.</p>noreply@esmo.org8d7a31cc-4316-426c-9a9b-fe53dece6133Thu, 28 Aug 2025 08:08:00 +00:00 Superior EFS and OS in Patients with Nonmetastatic Osteosarcoma and Unfavourable Prognosis when Adjuvant Mifamurtide is Combined with High-Dose Ifosfamide https://www.esmo.orgnull<p>Findings from the ISG/OS-2 and GEIS-33 studies</p>noreply@esmo.org71f4b205-e613-44f8-86f1-e6b1afc68c9eThu, 28 Aug 2025 08:08:00 +00:00 Molecular Analysis for Precision Oncology Congress 2025, Paris, France, 15-16 September https://www.esmo.orgnull<p>The Molecular Analysis for Precision Oncology Congress 2025 (MAP) will bring together leading experts to explore the latest advances in cancer research, with a focus on deepening the understanding of disease mechanism and enhancing strategies for prevention and interception</p>noreply@esmo.org8b521c78-d705-426c-af80-d640aafdba56Wed, 27 Aug 2025 07:08:00 +00:00 Combining Enzalutamide with Radium-223 Significantly Improves rPFS as First-Line Therapy for Patients with mCRPC https://www.esmo.orgnull<p>Findings from the PEACE-3 study</p>noreply@esmo.orgf7879b8d-5c1c-4259-8f0d-efe16d428097Wed, 27 Aug 2025 07:08:00 +00:00 AI and remote monitoring are shaping a new patient journey in oncology https://www.esmo.orgnull<p>Real world experience suggests that the integration of digital tools into cancer care may close current gaps in patient outcomes reporting</p>noreply@esmo.org34da15a5-c125-47bd-b755-aa2474d72593Tue, 26 Aug 2025 22:08:00 +00:00 In Memory of Håkan Mellstedt: Former ESMO President https://www.esmo.orgnull<p>It is with deep sadness that ESMO has learnt of the passing of Professor Håkan Mellstedt, who died recently at the age of 82</p>noreply@esmo.org7dc6e2e0-2732-4ef0-852d-5cd9c71daf1bTue, 26 Aug 2025 12:08:00 +00:00 EMA Recommends Granting a Conditional Marketing Authorisation for Obecabtagene Autoleucel https://www.esmo.orgnull<p>It is intended for the treatment of adults from 26 years of age with relapsed or refractory B cell precursor ALL</p>noreply@esmo.orgb883a1ba-0478-438c-b5ad-b855cbfc0d09Tue, 26 Aug 2025 07:08:00 +00:00 Additional 5 Years of AI Treatment Reduces Distant Recurrence Rates Among Postmenopausal Women Already Treated with at Least 5 Years of Endocrine Therapy https://www.esmo.orgnull<p>Findings from a meta-analysis performed by the Early Breast Cancer Trialists' Collaborative Group</p>noreply@esmo.orgaae366ec-0676-4745-8c5a-f3417ecafa3eMon, 25 Aug 2025 07:08:00 +00:00 FDA Grants Accelerated Approval to Dordaviprone for Diffuse Midline Glioma https://www.esmo.orgnull<p>Evidence for efficacy is based on results from the ONC006, ONC013, ONC014, ONC016 and ONC018 studies</p>noreply@esmo.orga619a127-a1d6-4f54-96e8-4bdf3e567f21Fri, 22 Aug 2025 07:08:00 +00:00 Clinical Benefit and Genomic Features Associations Observed with Pembrolizumab Plus Axitinib in Patients with Advanced Clear Cell RCC https://www.esmo.orgnull<p>Findings from the KEYNOTE-426 study</p>noreply@esmo.org36cbe128-7def-4a17-9bd8-c253a9dfb8aaThu, 21 Aug 2025 07:08:00 +00:00 Adagrasib Improves PFS Over Docetaxel in Patients with Previously Treated KRASG12C-mutated NSCLC https://www.esmo.orgnull<p>Findings from the KRYSTAL-12 study</p>noreply@esmo.org8c65622a-b33b-4f13-8f22-12eb2c009b82Wed, 20 Aug 2025 07:08:00 +00:00 No Survival Benefit from Adding Adjuvant Chemotherapy to Endocrine Therapy in Older Women with a Genomic Grade Index High-Risk ER-positive, HER2-negative Breast Cancer https://www.esmo.orgnull<p>Findings from the ASTER 70s study</p>noreply@esmo.org2d825557-d2eb-4f7f-acb9-251237054d65Tue, 19 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Belantamab Mafodotin https://www.esmo.orgnull<p>It is intended for the treatment of patients with relapsed or refractory multiple myeloma</p>noreply@esmo.org965f5a4a-9a84-430c-bc6f-e40ca62558f5Mon, 18 Aug 2025 07:08:00 +00:00 ESMO Joins the European Health Alliance on Alcohol (EHAA) Seeking to Reduce Preventable Cancer Cases Linked to Alcohol Use https://www.esmo.orgnull<p>With alcohol consumption increasing the risk of developing at least 7 types of cancer, ESMO considers it crucial that robust policy action - at all political levels - is taken to effectively address the impact of alcohol-related harm on human health, thus enhancing cancer prevention</p>noreply@esmo.org796a42df-36fd-4a93-9ee2-41fa00b14ba2Thu, 14 Aug 2025 09:08:00 +00:00 CLDN18.2-Specific CAR T-Cell Therapy Prolongs PFS in Patients with Previously Treated Advanced Gastric or Gastro-oesophageal Junction Cancer https://www.esmo.orgnull<p>Findings from the CT041-ST-01 study</p>noreply@esmo.orgbebed821-c39b-48c2-bce8-7c5c96e4a8dbThu, 14 Aug 2025 07:08:00 +00:00 FDA Approves Tafasitamab-cxix for Relapsed or Refractory Follicular Lymphoma https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the inMIND study</p>noreply@esmo.org5e4115df-3e7b-4e40-bf32-d67663bd25ceThu, 14 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Vorasidenib https://www.esmo.orgnull<p>It is intended for the treatment of adults and adolescents with low grade astrocytoma or oligodendroglioma with an <em>IDH1</em> R132 or <em>IDH2</em> R172 mutation</p>noreply@esmo.org33595183-53c1-46d7-8d11-8efbe77ad103Wed, 13 Aug 2025 07:08:00 +00:00 Postoperative Radioiodine Can Be Avoided in Patients with Low-Risk Differentiated Thyroid Cancer https://www.esmo.orgnull<p>Findings from the IoN&nbsp;study</p>noreply@esmo.orgf44a7b22-946b-4057-90c0-b17c5d006568Tue, 12 Aug 2025 07:08:00 +00:00 ESMO Recommendations on Cancer Care Reflected in UN ECOSOC Ministerial Declaration on Sustainable Development https://www.esmo.orgnull<p>At the conclusion of the 2025 High-Level Political Forum (HLPF) on Sustainable Development, UN Member States adopted a Ministerial Declaration reaffirming commitment to universal health coverage (UHC), resilient health systems, and tackling non-communicable diseases (NCDs) like cancer</p>noreply@esmo.org1bac8e44-2826-4e2e-941a-7cda78fe8ffaMon, 11 Aug 2025 07:08:00 +00:00 ESMO Newshttps://www.esmo.org/The latest news from ESMOen-GBnoreply@esmo.org242, 30 Aug 2025 08:08:39 +00:00242, 30 Aug 2025 08:08:39 +00:00 FDA Grants Accelerated Approval to Zongertinib for Non-squamous NSCLC with HER2 Tyrosine Kinase Domain Activating Mutations https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the Beamion LUNG-1 study</p>noreply@esmo.orgbb0dc137-253d-4b77-929b-1beb77fa87e2Fri, 29 Aug 2025 08:08:00 +00:00 Early-Stage and Locally Advanced NSCLC: ESMO Clinical Practice Guideline https://www.esmo.orgnull<p>This updated ESMO CPG provides diagnosis, staging, risk assessment, treatment and follow-up recommendations. It introduces new systemic treatments and innovative strategies, offering physicians practicing thoracic oncology advanced therapeutic options to improve outcomes and personalise care.</p>noreply@esmo.org8d7a31cc-4316-426c-9a9b-fe53dece6133Thu, 28 Aug 2025 08:08:00 +00:00 Superior EFS and OS in Patients with Nonmetastatic Osteosarcoma and Unfavourable Prognosis when Adjuvant Mifamurtide is Combined with High-Dose Ifosfamide https://www.esmo.orgnull<p>Findings from the ISG/OS-2 and GEIS-33 studies</p>noreply@esmo.org71f4b205-e613-44f8-86f1-e6b1afc68c9eThu, 28 Aug 2025 08:08:00 +00:00 Molecular Analysis for Precision Oncology Congress 2025, Paris, France, 15-16 September https://www.esmo.orgnull<p>The Molecular Analysis for Precision Oncology Congress 2025 (MAP) will bring together leading experts to explore the latest advances in cancer research, with a focus on deepening the understanding of disease mechanism and enhancing strategies for prevention and interception</p>noreply@esmo.org8b521c78-d705-426c-af80-d640aafdba56Wed, 27 Aug 2025 07:08:00 +00:00 Combining Enzalutamide with Radium-223 Significantly Improves rPFS as First-Line Therapy for Patients with mCRPC https://www.esmo.orgnull<p>Findings from the PEACE-3 study</p>noreply@esmo.orgf7879b8d-5c1c-4259-8f0d-efe16d428097Wed, 27 Aug 2025 07:08:00 +00:00 AI and remote monitoring are shaping a new patient journey in oncology https://www.esmo.orgnull<p>Real world experience suggests that the integration of digital tools into cancer care may close current gaps in patient outcomes reporting</p>noreply@esmo.org34da15a5-c125-47bd-b755-aa2474d72593Tue, 26 Aug 2025 22:08:00 +00:00 In Memory of Håkan Mellstedt: Former ESMO President https://www.esmo.orgnull<p>It is with deep sadness that ESMO has learnt of the passing of Professor Håkan Mellstedt, who died recently at the age of 82</p>noreply@esmo.org7dc6e2e0-2732-4ef0-852d-5cd9c71daf1bTue, 26 Aug 2025 12:08:00 +00:00 EMA Recommends Granting a Conditional Marketing Authorisation for Obecabtagene Autoleucel https://www.esmo.orgnull<p>It is intended for the treatment of adults from 26 years of age with relapsed or refractory B cell precursor ALL</p>noreply@esmo.orgb883a1ba-0478-438c-b5ad-b855cbfc0d09Tue, 26 Aug 2025 07:08:00 +00:00 Additional 5 Years of AI Treatment Reduces Distant Recurrence Rates Among Postmenopausal Women Already Treated with at Least 5 Years of Endocrine Therapy https://www.esmo.orgnull<p>Findings from a meta-analysis performed by the Early Breast Cancer Trialists' Collaborative Group</p>noreply@esmo.orgaae366ec-0676-4745-8c5a-f3417ecafa3eMon, 25 Aug 2025 07:08:00 +00:00 FDA Grants Accelerated Approval to Dordaviprone for Diffuse Midline Glioma https://www.esmo.orgnull<p>Evidence for efficacy is based on results from the ONC006, ONC013, ONC014, ONC016 and ONC018 studies</p>noreply@esmo.orga619a127-a1d6-4f54-96e8-4bdf3e567f21Fri, 22 Aug 2025 07:08:00 +00:00 Clinical Benefit and Genomic Features Associations Observed with Pembrolizumab Plus Axitinib in Patients with Advanced Clear Cell RCC https://www.esmo.orgnull<p>Findings from the KEYNOTE-426 study</p>noreply@esmo.org36cbe128-7def-4a17-9bd8-c253a9dfb8aaThu, 21 Aug 2025 07:08:00 +00:00 Adagrasib Improves PFS Over Docetaxel in Patients with Previously Treated KRASG12C-mutated NSCLC https://www.esmo.orgnull<p>Findings from the KRYSTAL-12 study</p>noreply@esmo.org8c65622a-b33b-4f13-8f22-12eb2c009b82Wed, 20 Aug 2025 07:08:00 +00:00 No Survival Benefit from Adding Adjuvant Chemotherapy to Endocrine Therapy in Older Women with a Genomic Grade Index High-Risk ER-positive, HER2-negative Breast Cancer https://www.esmo.orgnull<p>Findings from the ASTER 70s study</p>noreply@esmo.org2d825557-d2eb-4f7f-acb9-251237054d65Tue, 19 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Belantamab Mafodotin https://www.esmo.orgnull<p>It is intended for the treatment of patients with relapsed or refractory multiple myeloma</p>noreply@esmo.org965f5a4a-9a84-430c-bc6f-e40ca62558f5Mon, 18 Aug 2025 07:08:00 +00:00 ESMO Joins the European Health Alliance on Alcohol (EHAA) Seeking to Reduce Preventable Cancer Cases Linked to Alcohol Use https://www.esmo.orgnull<p>With alcohol consumption increasing the risk of developing at least 7 types of cancer, ESMO considers it crucial that robust policy action - at all political levels - is taken to effectively address the impact of alcohol-related harm on human health, thus enhancing cancer prevention</p>noreply@esmo.org796a42df-36fd-4a93-9ee2-41fa00b14ba2Thu, 14 Aug 2025 09:08:00 +00:00 CLDN18.2-Specific CAR T-Cell Therapy Prolongs PFS in Patients with Previously Treated Advanced Gastric or Gastro-oesophageal Junction Cancer https://www.esmo.orgnull<p>Findings from the CT041-ST-01 study</p>noreply@esmo.orgbebed821-c39b-48c2-bce8-7c5c96e4a8dbThu, 14 Aug 2025 07:08:00 +00:00 FDA Approves Tafasitamab-cxix for Relapsed or Refractory Follicular Lymphoma https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the inMIND study</p>noreply@esmo.org5e4115df-3e7b-4e40-bf32-d67663bd25ceThu, 14 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Vorasidenib https://www.esmo.orgnull<p>It is intended for the treatment of adults and adolescents with low grade astrocytoma or oligodendroglioma with an <em>IDH1</em> R132 or <em>IDH2</em> R172 mutation</p>noreply@esmo.org33595183-53c1-46d7-8d11-8efbe77ad103Wed, 13 Aug 2025 07:08:00 +00:00 Postoperative Radioiodine Can Be Avoided in Patients with Low-Risk Differentiated Thyroid Cancer https://www.esmo.orgnull<p>Findings from the IoN&nbsp;study</p>noreply@esmo.orgf44a7b22-946b-4057-90c0-b17c5d006568Tue, 12 Aug 2025 07:08:00 +00:00 ESMO Recommendations on Cancer Care Reflected in UN ECOSOC Ministerial Declaration on Sustainable Development https://www.esmo.orgnull<p>At the conclusion of the 2025 High-Level Political Forum (HLPF) on Sustainable Development, UN Member States adopted a Ministerial Declaration reaffirming commitment to universal health coverage (UHC), resilient health systems, and tackling non-communicable diseases (NCDs) like cancer</p>noreply@esmo.org1bac8e44-2826-4e2e-941a-7cda78fe8ffaMon, 11 Aug 2025 07:08:00 +00:00 ESMO Newshttps://www.esmo.org/The latest news from ESMOen-GBnoreply@esmo.org242, 30 Aug 2025 08:08:47 +00:00242, 30 Aug 2025 08:08:47 +00:00 FDA Grants Accelerated Approval to Zongertinib for Non-squamous NSCLC with HER2 Tyrosine Kinase Domain Activating Mutations https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the Beamion LUNG-1 study</p>noreply@esmo.orgbb0dc137-253d-4b77-929b-1beb77fa87e2Fri, 29 Aug 2025 08:08:00 +00:00 Early-Stage and Locally Advanced NSCLC: ESMO Clinical Practice Guideline https://www.esmo.orgnull<p>This updated ESMO CPG provides diagnosis, staging, risk assessment, treatment and follow-up recommendations. It introduces new systemic treatments and innovative strategies, offering physicians practicing thoracic oncology advanced therapeutic options to improve outcomes and personalise care.</p>noreply@esmo.org8d7a31cc-4316-426c-9a9b-fe53dece6133Thu, 28 Aug 2025 08:08:00 +00:00 Superior EFS and OS in Patients with Nonmetastatic Osteosarcoma and Unfavourable Prognosis when Adjuvant Mifamurtide is Combined with High-Dose Ifosfamide https://www.esmo.orgnull<p>Findings from the ISG/OS-2 and GEIS-33 studies</p>noreply@esmo.org71f4b205-e613-44f8-86f1-e6b1afc68c9eThu, 28 Aug 2025 08:08:00 +00:00 Molecular Analysis for Precision Oncology Congress 2025, Paris, France, 15-16 September https://www.esmo.orgnull<p>The Molecular Analysis for Precision Oncology Congress 2025 (MAP) will bring together leading experts to explore the latest advances in cancer research, with a focus on deepening the understanding of disease mechanism and enhancing strategies for prevention and interception</p>noreply@esmo.org8b521c78-d705-426c-af80-d640aafdba56Wed, 27 Aug 2025 07:08:00 +00:00 Combining Enzalutamide with Radium-223 Significantly Improves rPFS as First-Line Therapy for Patients with mCRPC https://www.esmo.orgnull<p>Findings from the PEACE-3 study</p>noreply@esmo.orgf7879b8d-5c1c-4259-8f0d-efe16d428097Wed, 27 Aug 2025 07:08:00 +00:00 AI and remote monitoring are shaping a new patient journey in oncology https://www.esmo.orgnull<p>Real world experience suggests that the integration of digital tools into cancer care may close current gaps in patient outcomes reporting</p>noreply@esmo.org34da15a5-c125-47bd-b755-aa2474d72593Tue, 26 Aug 2025 22:08:00 +00:00 In Memory of Håkan Mellstedt: Former ESMO President https://www.esmo.orgnull<p>It is with deep sadness that ESMO has learnt of the passing of Professor Håkan Mellstedt, who died recently at the age of 82</p>noreply@esmo.org7dc6e2e0-2732-4ef0-852d-5cd9c71daf1bTue, 26 Aug 2025 12:08:00 +00:00 EMA Recommends Granting a Conditional Marketing Authorisation for Obecabtagene Autoleucel https://www.esmo.orgnull<p>It is intended for the treatment of adults from 26 years of age with relapsed or refractory B cell precursor ALL</p>noreply@esmo.orgb883a1ba-0478-438c-b5ad-b855cbfc0d09Tue, 26 Aug 2025 07:08:00 +00:00 Additional 5 Years of AI Treatment Reduces Distant Recurrence Rates Among Postmenopausal Women Already Treated with at Least 5 Years of Endocrine Therapy https://www.esmo.orgnull<p>Findings from a meta-analysis performed by the Early Breast Cancer Trialists' Collaborative Group</p>noreply@esmo.orgaae366ec-0676-4745-8c5a-f3417ecafa3eMon, 25 Aug 2025 07:08:00 +00:00 FDA Grants Accelerated Approval to Dordaviprone for Diffuse Midline Glioma https://www.esmo.orgnull<p>Evidence for efficacy is based on results from the ONC006, ONC013, ONC014, ONC016 and ONC018 studies</p>noreply@esmo.orga619a127-a1d6-4f54-96e8-4bdf3e567f21Fri, 22 Aug 2025 07:08:00 +00:00 Clinical Benefit and Genomic Features Associations Observed with Pembrolizumab Plus Axitinib in Patients with Advanced Clear Cell RCC https://www.esmo.orgnull<p>Findings from the KEYNOTE-426 study</p>noreply@esmo.org36cbe128-7def-4a17-9bd8-c253a9dfb8aaThu, 21 Aug 2025 07:08:00 +00:00 Adagrasib Improves PFS Over Docetaxel in Patients with Previously Treated KRASG12C-mutated NSCLC https://www.esmo.orgnull<p>Findings from the KRYSTAL-12 study</p>noreply@esmo.org8c65622a-b33b-4f13-8f22-12eb2c009b82Wed, 20 Aug 2025 07:08:00 +00:00 No Survival Benefit from Adding Adjuvant Chemotherapy to Endocrine Therapy in Older Women with a Genomic Grade Index High-Risk ER-positive, HER2-negative Breast Cancer https://www.esmo.orgnull<p>Findings from the ASTER 70s study</p>noreply@esmo.org2d825557-d2eb-4f7f-acb9-251237054d65Tue, 19 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Belantamab Mafodotin https://www.esmo.orgnull<p>It is intended for the treatment of patients with relapsed or refractory multiple myeloma</p>noreply@esmo.org965f5a4a-9a84-430c-bc6f-e40ca62558f5Mon, 18 Aug 2025 07:08:00 +00:00 ESMO Joins the European Health Alliance on Alcohol (EHAA) Seeking to Reduce Preventable Cancer Cases Linked to Alcohol Use https://www.esmo.orgnull<p>With alcohol consumption increasing the risk of developing at least 7 types of cancer, ESMO considers it crucial that robust policy action - at all political levels - is taken to effectively address the impact of alcohol-related harm on human health, thus enhancing cancer prevention</p>noreply@esmo.org796a42df-36fd-4a93-9ee2-41fa00b14ba2Thu, 14 Aug 2025 09:08:00 +00:00 CLDN18.2-Specific CAR T-Cell Therapy Prolongs PFS in Patients with Previously Treated Advanced Gastric or Gastro-oesophageal Junction Cancer https://www.esmo.orgnull<p>Findings from the CT041-ST-01 study</p>noreply@esmo.orgbebed821-c39b-48c2-bce8-7c5c96e4a8dbThu, 14 Aug 2025 07:08:00 +00:00 FDA Approves Tafasitamab-cxix for Relapsed or Refractory Follicular Lymphoma https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the inMIND study</p>noreply@esmo.org5e4115df-3e7b-4e40-bf32-d67663bd25ceThu, 14 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Vorasidenib https://www.esmo.orgnull<p>It is intended for the treatment of adults and adolescents with low grade astrocytoma or oligodendroglioma with an <em>IDH1</em> R132 or <em>IDH2</em> R172 mutation</p>noreply@esmo.org33595183-53c1-46d7-8d11-8efbe77ad103Wed, 13 Aug 2025 07:08:00 +00:00 Postoperative Radioiodine Can Be Avoided in Patients with Low-Risk Differentiated Thyroid Cancer https://www.esmo.orgnull<p>Findings from the IoN&nbsp;study</p>noreply@esmo.orgf44a7b22-946b-4057-90c0-b17c5d006568Tue, 12 Aug 2025 07:08:00 +00:00 ESMO Recommendations on Cancer Care Reflected in UN ECOSOC Ministerial Declaration on Sustainable Development https://www.esmo.orgnull<p>At the conclusion of the 2025 High-Level Political Forum (HLPF) on Sustainable Development, UN Member States adopted a Ministerial Declaration reaffirming commitment to universal health coverage (UHC), resilient health systems, and tackling non-communicable diseases (NCDs) like cancer</p>noreply@esmo.org1bac8e44-2826-4e2e-941a-7cda78fe8ffaMon, 11 Aug 2025 07:08:00 +00:00 ESMO Newshttps://www.esmo.org/The latest news from ESMOen-GBnoreply@esmo.org242, 30 Aug 2025 08:08:89 +00:00242, 30 Aug 2025 08:08:89 +00:00 FDA Grants Accelerated Approval to Zongertinib for Non-squamous NSCLC with HER2 Tyrosine Kinase Domain Activating Mutations https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the Beamion LUNG-1 study</p>noreply@esmo.orgbb0dc137-253d-4b77-929b-1beb77fa87e2Fri, 29 Aug 2025 08:08:00 +00:00 Early-Stage and Locally Advanced NSCLC: ESMO Clinical Practice Guideline https://www.esmo.orgnull<p>This updated ESMO CPG provides diagnosis, staging, risk assessment, treatment and follow-up recommendations. It introduces new systemic treatments and innovative strategies, offering physicians practicing thoracic oncology advanced therapeutic options to improve outcomes and personalise care.</p>noreply@esmo.org8d7a31cc-4316-426c-9a9b-fe53dece6133Thu, 28 Aug 2025 08:08:00 +00:00 Superior EFS and OS in Patients with Nonmetastatic Osteosarcoma and Unfavourable Prognosis when Adjuvant Mifamurtide is Combined with High-Dose Ifosfamide https://www.esmo.orgnull<p>Findings from the ISG/OS-2 and GEIS-33 studies</p>noreply@esmo.org71f4b205-e613-44f8-86f1-e6b1afc68c9eThu, 28 Aug 2025 08:08:00 +00:00 Molecular Analysis for Precision Oncology Congress 2025, Paris, France, 15-16 September https://www.esmo.orgnull<p>The Molecular Analysis for Precision Oncology Congress 2025 (MAP) will bring together leading experts to explore the latest advances in cancer research, with a focus on deepening the understanding of disease mechanism and enhancing strategies for prevention and interception</p>noreply@esmo.org8b521c78-d705-426c-af80-d640aafdba56Wed, 27 Aug 2025 07:08:00 +00:00 Combining Enzalutamide with Radium-223 Significantly Improves rPFS as First-Line Therapy for Patients with mCRPC https://www.esmo.orgnull<p>Findings from the PEACE-3 study</p>noreply@esmo.orgf7879b8d-5c1c-4259-8f0d-efe16d428097Wed, 27 Aug 2025 07:08:00 +00:00 AI and remote monitoring are shaping a new patient journey in oncology https://www.esmo.orgnull<p>Real world experience suggests that the integration of digital tools into cancer care may close current gaps in patient outcomes reporting</p>noreply@esmo.org34da15a5-c125-47bd-b755-aa2474d72593Tue, 26 Aug 2025 22:08:00 +00:00 In Memory of Håkan Mellstedt: Former ESMO President https://www.esmo.orgnull<p>It is with deep sadness that ESMO has learnt of the passing of Professor Håkan Mellstedt, who died recently at the age of 82</p>noreply@esmo.org7dc6e2e0-2732-4ef0-852d-5cd9c71daf1bTue, 26 Aug 2025 12:08:00 +00:00 EMA Recommends Granting a Conditional Marketing Authorisation for Obecabtagene Autoleucel https://www.esmo.orgnull<p>It is intended for the treatment of adults from 26 years of age with relapsed or refractory B cell precursor ALL</p>noreply@esmo.orgb883a1ba-0478-438c-b5ad-b855cbfc0d09Tue, 26 Aug 2025 07:08:00 +00:00 Additional 5 Years of AI Treatment Reduces Distant Recurrence Rates Among Postmenopausal Women Already Treated with at Least 5 Years of Endocrine Therapy https://www.esmo.orgnull<p>Findings from a meta-analysis performed by the Early Breast Cancer Trialists' Collaborative Group</p>noreply@esmo.orgaae366ec-0676-4745-8c5a-f3417ecafa3eMon, 25 Aug 2025 07:08:00 +00:00 FDA Grants Accelerated Approval to Dordaviprone for Diffuse Midline Glioma https://www.esmo.orgnull<p>Evidence for efficacy is based on results from the ONC006, ONC013, ONC014, ONC016 and ONC018 studies</p>noreply@esmo.orga619a127-a1d6-4f54-96e8-4bdf3e567f21Fri, 22 Aug 2025 07:08:00 +00:00 Clinical Benefit and Genomic Features Associations Observed with Pembrolizumab Plus Axitinib in Patients with Advanced Clear Cell RCC https://www.esmo.orgnull<p>Findings from the KEYNOTE-426 study</p>noreply@esmo.org36cbe128-7def-4a17-9bd8-c253a9dfb8aaThu, 21 Aug 2025 07:08:00 +00:00 Adagrasib Improves PFS Over Docetaxel in Patients with Previously Treated KRASG12C-mutated NSCLC https://www.esmo.orgnull<p>Findings from the KRYSTAL-12 study</p>noreply@esmo.org8c65622a-b33b-4f13-8f22-12eb2c009b82Wed, 20 Aug 2025 07:08:00 +00:00 No Survival Benefit from Adding Adjuvant Chemotherapy to Endocrine Therapy in Older Women with a Genomic Grade Index High-Risk ER-positive, HER2-negative Breast Cancer https://www.esmo.orgnull<p>Findings from the ASTER 70s study</p>noreply@esmo.org2d825557-d2eb-4f7f-acb9-251237054d65Tue, 19 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Belantamab Mafodotin https://www.esmo.orgnull<p>It is intended for the treatment of patients with relapsed or refractory multiple myeloma</p>noreply@esmo.org965f5a4a-9a84-430c-bc6f-e40ca62558f5Mon, 18 Aug 2025 07:08:00 +00:00 ESMO Joins the European Health Alliance on Alcohol (EHAA) Seeking to Reduce Preventable Cancer Cases Linked to Alcohol Use https://www.esmo.orgnull<p>With alcohol consumption increasing the risk of developing at least 7 types of cancer, ESMO considers it crucial that robust policy action - at all political levels - is taken to effectively address the impact of alcohol-related harm on human health, thus enhancing cancer prevention</p>noreply@esmo.org796a42df-36fd-4a93-9ee2-41fa00b14ba2Thu, 14 Aug 2025 09:08:00 +00:00 CLDN18.2-Specific CAR T-Cell Therapy Prolongs PFS in Patients with Previously Treated Advanced Gastric or Gastro-oesophageal Junction Cancer https://www.esmo.orgnull<p>Findings from the CT041-ST-01 study</p>noreply@esmo.orgbebed821-c39b-48c2-bce8-7c5c96e4a8dbThu, 14 Aug 2025 07:08:00 +00:00 FDA Approves Tafasitamab-cxix for Relapsed or Refractory Follicular Lymphoma https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the inMIND study</p>noreply@esmo.org5e4115df-3e7b-4e40-bf32-d67663bd25ceThu, 14 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Vorasidenib https://www.esmo.orgnull<p>It is intended for the treatment of adults and adolescents with low grade astrocytoma or oligodendroglioma with an <em>IDH1</em> R132 or <em>IDH2</em> R172 mutation</p>noreply@esmo.org33595183-53c1-46d7-8d11-8efbe77ad103Wed, 13 Aug 2025 07:08:00 +00:00 Postoperative Radioiodine Can Be Avoided in Patients with Low-Risk Differentiated Thyroid Cancer https://www.esmo.orgnull<p>Findings from the IoN&nbsp;study</p>noreply@esmo.orgf44a7b22-946b-4057-90c0-b17c5d006568Tue, 12 Aug 2025 07:08:00 +00:00 ESMO Recommendations on Cancer Care Reflected in UN ECOSOC Ministerial Declaration on Sustainable Development https://www.esmo.orgnull<p>At the conclusion of the 2025 High-Level Political Forum (HLPF) on Sustainable Development, UN Member States adopted a Ministerial Declaration reaffirming commitment to universal health coverage (UHC), resilient health systems, and tackling non-communicable diseases (NCDs) like cancer</p>noreply@esmo.org1bac8e44-2826-4e2e-941a-7cda78fe8ffaMon, 11 Aug 2025 07:08:00 +00:00 ESMO Newshttps://www.esmo.org/The latest news from ESMOen-GBnoreply@esmo.org242, 30 Aug 2025 08:08:74 +00:00242, 30 Aug 2025 08:08:74 +00:00 FDA Grants Accelerated Approval to Zongertinib for Non-squamous NSCLC with HER2 Tyrosine Kinase Domain Activating Mutations https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the Beamion LUNG-1 study</p>noreply@esmo.orgbb0dc137-253d-4b77-929b-1beb77fa87e2Fri, 29 Aug 2025 08:08:00 +00:00 Early-Stage and Locally Advanced NSCLC: ESMO Clinical Practice Guideline https://www.esmo.orgnull<p>This updated ESMO CPG provides diagnosis, staging, risk assessment, treatment and follow-up recommendations. It introduces new systemic treatments and innovative strategies, offering physicians practicing thoracic oncology advanced therapeutic options to improve outcomes and personalise care.</p>noreply@esmo.org8d7a31cc-4316-426c-9a9b-fe53dece6133Thu, 28 Aug 2025 08:08:00 +00:00 Superior EFS and OS in Patients with Nonmetastatic Osteosarcoma and Unfavourable Prognosis when Adjuvant Mifamurtide is Combined with High-Dose Ifosfamide https://www.esmo.orgnull<p>Findings from the ISG/OS-2 and GEIS-33 studies</p>noreply@esmo.org71f4b205-e613-44f8-86f1-e6b1afc68c9eThu, 28 Aug 2025 08:08:00 +00:00 Molecular Analysis for Precision Oncology Congress 2025, Paris, France, 15-16 September https://www.esmo.orgnull<p>The Molecular Analysis for Precision Oncology Congress 2025 (MAP) will bring together leading experts to explore the latest advances in cancer research, with a focus on deepening the understanding of disease mechanism and enhancing strategies for prevention and interception</p>noreply@esmo.org8b521c78-d705-426c-af80-d640aafdba56Wed, 27 Aug 2025 07:08:00 +00:00 Combining Enzalutamide with Radium-223 Significantly Improves rPFS as First-Line Therapy for Patients with mCRPC https://www.esmo.orgnull<p>Findings from the PEACE-3 study</p>noreply@esmo.orgf7879b8d-5c1c-4259-8f0d-efe16d428097Wed, 27 Aug 2025 07:08:00 +00:00 AI and remote monitoring are shaping a new patient journey in oncology https://www.esmo.orgnull<p>Real world experience suggests that the integration of digital tools into cancer care may close current gaps in patient outcomes reporting</p>noreply@esmo.org34da15a5-c125-47bd-b755-aa2474d72593Tue, 26 Aug 2025 22:08:00 +00:00 In Memory of Håkan Mellstedt: Former ESMO President https://www.esmo.orgnull<p>It is with deep sadness that ESMO has learnt of the passing of Professor Håkan Mellstedt, who died recently at the age of 82</p>noreply@esmo.org7dc6e2e0-2732-4ef0-852d-5cd9c71daf1bTue, 26 Aug 2025 12:08:00 +00:00 EMA Recommends Granting a Conditional Marketing Authorisation for Obecabtagene Autoleucel https://www.esmo.orgnull<p>It is intended for the treatment of adults from 26 years of age with relapsed or refractory B cell precursor ALL</p>noreply@esmo.orgb883a1ba-0478-438c-b5ad-b855cbfc0d09Tue, 26 Aug 2025 07:08:00 +00:00 Additional 5 Years of AI Treatment Reduces Distant Recurrence Rates Among Postmenopausal Women Already Treated with at Least 5 Years of Endocrine Therapy https://www.esmo.orgnull<p>Findings from a meta-analysis performed by the Early Breast Cancer Trialists' Collaborative Group</p>noreply@esmo.orgaae366ec-0676-4745-8c5a-f3417ecafa3eMon, 25 Aug 2025 07:08:00 +00:00 FDA Grants Accelerated Approval to Dordaviprone for Diffuse Midline Glioma https://www.esmo.orgnull<p>Evidence for efficacy is based on results from the ONC006, ONC013, ONC014, ONC016 and ONC018 studies</p>noreply@esmo.orga619a127-a1d6-4f54-96e8-4bdf3e567f21Fri, 22 Aug 2025 07:08:00 +00:00 Clinical Benefit and Genomic Features Associations Observed with Pembrolizumab Plus Axitinib in Patients with Advanced Clear Cell RCC https://www.esmo.orgnull<p>Findings from the KEYNOTE-426 study</p>noreply@esmo.org36cbe128-7def-4a17-9bd8-c253a9dfb8aaThu, 21 Aug 2025 07:08:00 +00:00 Adagrasib Improves PFS Over Docetaxel in Patients with Previously Treated KRASG12C-mutated NSCLC https://www.esmo.orgnull<p>Findings from the KRYSTAL-12 study</p>noreply@esmo.org8c65622a-b33b-4f13-8f22-12eb2c009b82Wed, 20 Aug 2025 07:08:00 +00:00 No Survival Benefit from Adding Adjuvant Chemotherapy to Endocrine Therapy in Older Women with a Genomic Grade Index High-Risk ER-positive, HER2-negative Breast Cancer https://www.esmo.orgnull<p>Findings from the ASTER 70s study</p>noreply@esmo.org2d825557-d2eb-4f7f-acb9-251237054d65Tue, 19 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Belantamab Mafodotin https://www.esmo.orgnull<p>It is intended for the treatment of patients with relapsed or refractory multiple myeloma</p>noreply@esmo.org965f5a4a-9a84-430c-bc6f-e40ca62558f5Mon, 18 Aug 2025 07:08:00 +00:00 ESMO Joins the European Health Alliance on Alcohol (EHAA) Seeking to Reduce Preventable Cancer Cases Linked to Alcohol Use https://www.esmo.orgnull<p>With alcohol consumption increasing the risk of developing at least 7 types of cancer, ESMO considers it crucial that robust policy action - at all political levels - is taken to effectively address the impact of alcohol-related harm on human health, thus enhancing cancer prevention</p>noreply@esmo.org796a42df-36fd-4a93-9ee2-41fa00b14ba2Thu, 14 Aug 2025 09:08:00 +00:00 CLDN18.2-Specific CAR T-Cell Therapy Prolongs PFS in Patients with Previously Treated Advanced Gastric or Gastro-oesophageal Junction Cancer https://www.esmo.orgnull<p>Findings from the CT041-ST-01 study</p>noreply@esmo.orgbebed821-c39b-48c2-bce8-7c5c96e4a8dbThu, 14 Aug 2025 07:08:00 +00:00 FDA Approves Tafasitamab-cxix for Relapsed or Refractory Follicular Lymphoma https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the inMIND study</p>noreply@esmo.org5e4115df-3e7b-4e40-bf32-d67663bd25ceThu, 14 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Vorasidenib https://www.esmo.orgnull<p>It is intended for the treatment of adults and adolescents with low grade astrocytoma or oligodendroglioma with an <em>IDH1</em> R132 or <em>IDH2</em> R172 mutation</p>noreply@esmo.org33595183-53c1-46d7-8d11-8efbe77ad103Wed, 13 Aug 2025 07:08:00 +00:00 Postoperative Radioiodine Can Be Avoided in Patients with Low-Risk Differentiated Thyroid Cancer https://www.esmo.orgnull<p>Findings from the IoN&nbsp;study</p>noreply@esmo.orgf44a7b22-946b-4057-90c0-b17c5d006568Tue, 12 Aug 2025 07:08:00 +00:00 ESMO Recommendations on Cancer Care Reflected in UN ECOSOC Ministerial Declaration on Sustainable Development https://www.esmo.orgnull<p>At the conclusion of the 2025 High-Level Political Forum (HLPF) on Sustainable Development, UN Member States adopted a Ministerial Declaration reaffirming commitment to universal health coverage (UHC), resilient health systems, and tackling non-communicable diseases (NCDs) like cancer</p>noreply@esmo.org1bac8e44-2826-4e2e-941a-7cda78fe8ffaMon, 11 Aug 2025 07:08:00 +00:00 ESMO Newshttps://www.esmo.org/The latest news from ESMOen-GBnoreply@esmo.org242, 30 Aug 2025 08:08:41 +00:00242, 30 Aug 2025 08:08:41 +00:00 FDA Grants Accelerated Approval to Zongertinib for Non-squamous NSCLC with HER2 Tyrosine Kinase Domain Activating Mutations https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the Beamion LUNG-1 study</p>noreply@esmo.orgbb0dc137-253d-4b77-929b-1beb77fa87e2Fri, 29 Aug 2025 08:08:00 +00:00 Early-Stage and Locally Advanced NSCLC: ESMO Clinical Practice Guideline https://www.esmo.orgnull<p>This updated ESMO CPG provides diagnosis, staging, risk assessment, treatment and follow-up recommendations. It introduces new systemic treatments and innovative strategies, offering physicians practicing thoracic oncology advanced therapeutic options to improve outcomes and personalise care.</p>noreply@esmo.org8d7a31cc-4316-426c-9a9b-fe53dece6133Thu, 28 Aug 2025 08:08:00 +00:00 Superior EFS and OS in Patients with Nonmetastatic Osteosarcoma and Unfavourable Prognosis when Adjuvant Mifamurtide is Combined with High-Dose Ifosfamide https://www.esmo.orgnull<p>Findings from the ISG/OS-2 and GEIS-33 studies</p>noreply@esmo.org71f4b205-e613-44f8-86f1-e6b1afc68c9eThu, 28 Aug 2025 08:08:00 +00:00 Molecular Analysis for Precision Oncology Congress 2025, Paris, France, 15-16 September https://www.esmo.orgnull<p>The Molecular Analysis for Precision Oncology Congress 2025 (MAP) will bring together leading experts to explore the latest advances in cancer research, with a focus on deepening the understanding of disease mechanism and enhancing strategies for prevention and interception</p>noreply@esmo.org8b521c78-d705-426c-af80-d640aafdba56Wed, 27 Aug 2025 07:08:00 +00:00 Combining Enzalutamide with Radium-223 Significantly Improves rPFS as First-Line Therapy for Patients with mCRPC https://www.esmo.orgnull<p>Findings from the PEACE-3 study</p>noreply@esmo.orgf7879b8d-5c1c-4259-8f0d-efe16d428097Wed, 27 Aug 2025 07:08:00 +00:00 AI and remote monitoring are shaping a new patient journey in oncology https://www.esmo.orgnull<p>Real world experience suggests that the integration of digital tools into cancer care may close current gaps in patient outcomes reporting</p>noreply@esmo.org34da15a5-c125-47bd-b755-aa2474d72593Tue, 26 Aug 2025 22:08:00 +00:00 In Memory of Håkan Mellstedt: Former ESMO President https://www.esmo.orgnull<p>It is with deep sadness that ESMO has learnt of the passing of Professor Håkan Mellstedt, who died recently at the age of 82</p>noreply@esmo.org7dc6e2e0-2732-4ef0-852d-5cd9c71daf1bTue, 26 Aug 2025 12:08:00 +00:00 EMA Recommends Granting a Conditional Marketing Authorisation for Obecabtagene Autoleucel https://www.esmo.orgnull<p>It is intended for the treatment of adults from 26 years of age with relapsed or refractory B cell precursor ALL</p>noreply@esmo.orgb883a1ba-0478-438c-b5ad-b855cbfc0d09Tue, 26 Aug 2025 07:08:00 +00:00 Additional 5 Years of AI Treatment Reduces Distant Recurrence Rates Among Postmenopausal Women Already Treated with at Least 5 Years of Endocrine Therapy https://www.esmo.orgnull<p>Findings from a meta-analysis performed by the Early Breast Cancer Trialists' Collaborative Group</p>noreply@esmo.orgaae366ec-0676-4745-8c5a-f3417ecafa3eMon, 25 Aug 2025 07:08:00 +00:00 FDA Grants Accelerated Approval to Dordaviprone for Diffuse Midline Glioma https://www.esmo.orgnull<p>Evidence for efficacy is based on results from the ONC006, ONC013, ONC014, ONC016 and ONC018 studies</p>noreply@esmo.orga619a127-a1d6-4f54-96e8-4bdf3e567f21Fri, 22 Aug 2025 07:08:00 +00:00 Clinical Benefit and Genomic Features Associations Observed with Pembrolizumab Plus Axitinib in Patients with Advanced Clear Cell RCC https://www.esmo.orgnull<p>Findings from the KEYNOTE-426 study</p>noreply@esmo.org36cbe128-7def-4a17-9bd8-c253a9dfb8aaThu, 21 Aug 2025 07:08:00 +00:00 Adagrasib Improves PFS Over Docetaxel in Patients with Previously Treated KRASG12C-mutated NSCLC https://www.esmo.orgnull<p>Findings from the KRYSTAL-12 study</p>noreply@esmo.org8c65622a-b33b-4f13-8f22-12eb2c009b82Wed, 20 Aug 2025 07:08:00 +00:00 No Survival Benefit from Adding Adjuvant Chemotherapy to Endocrine Therapy in Older Women with a Genomic Grade Index High-Risk ER-positive, HER2-negative Breast Cancer https://www.esmo.orgnull<p>Findings from the ASTER 70s study</p>noreply@esmo.org2d825557-d2eb-4f7f-acb9-251237054d65Tue, 19 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Belantamab Mafodotin https://www.esmo.orgnull<p>It is intended for the treatment of patients with relapsed or refractory multiple myeloma</p>noreply@esmo.org965f5a4a-9a84-430c-bc6f-e40ca62558f5Mon, 18 Aug 2025 07:08:00 +00:00 ESMO Joins the European Health Alliance on Alcohol (EHAA) Seeking to Reduce Preventable Cancer Cases Linked to Alcohol Use https://www.esmo.orgnull<p>With alcohol consumption increasing the risk of developing at least 7 types of cancer, ESMO considers it crucial that robust policy action - at all political levels - is taken to effectively address the impact of alcohol-related harm on human health, thus enhancing cancer prevention</p>noreply@esmo.org796a42df-36fd-4a93-9ee2-41fa00b14ba2Thu, 14 Aug 2025 09:08:00 +00:00 CLDN18.2-Specific CAR T-Cell Therapy Prolongs PFS in Patients with Previously Treated Advanced Gastric or Gastro-oesophageal Junction Cancer https://www.esmo.orgnull<p>Findings from the CT041-ST-01 study</p>noreply@esmo.orgbebed821-c39b-48c2-bce8-7c5c96e4a8dbThu, 14 Aug 2025 07:08:00 +00:00 FDA Approves Tafasitamab-cxix for Relapsed or Refractory Follicular Lymphoma https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the inMIND study</p>noreply@esmo.org5e4115df-3e7b-4e40-bf32-d67663bd25ceThu, 14 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Vorasidenib https://www.esmo.orgnull<p>It is intended for the treatment of adults and adolescents with low grade astrocytoma or oligodendroglioma with an <em>IDH1</em> R132 or <em>IDH2</em> R172 mutation</p>noreply@esmo.org33595183-53c1-46d7-8d11-8efbe77ad103Wed, 13 Aug 2025 07:08:00 +00:00 Postoperative Radioiodine Can Be Avoided in Patients with Low-Risk Differentiated Thyroid Cancer https://www.esmo.orgnull<p>Findings from the IoN&nbsp;study</p>noreply@esmo.orgf44a7b22-946b-4057-90c0-b17c5d006568Tue, 12 Aug 2025 07:08:00 +00:00 ESMO Recommendations on Cancer Care Reflected in UN ECOSOC Ministerial Declaration on Sustainable Development https://www.esmo.orgnull<p>At the conclusion of the 2025 High-Level Political Forum (HLPF) on Sustainable Development, UN Member States adopted a Ministerial Declaration reaffirming commitment to universal health coverage (UHC), resilient health systems, and tackling non-communicable diseases (NCDs) like cancer</p>noreply@esmo.org1bac8e44-2826-4e2e-941a-7cda78fe8ffaMon, 11 Aug 2025 07:08:00 +00:00 ESMO Newshttps://www.esmo.org/The latest news from ESMOen-GBnoreply@esmo.org242, 30 Aug 2025 08:08:51 +00:00242, 30 Aug 2025 08:08:51 +00:00 FDA Grants Accelerated Approval to Zongertinib for Non-squamous NSCLC with HER2 Tyrosine Kinase Domain Activating Mutations https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the Beamion LUNG-1 study</p>noreply@esmo.orgbb0dc137-253d-4b77-929b-1beb77fa87e2Fri, 29 Aug 2025 08:08:00 +00:00 Early-Stage and Locally Advanced NSCLC: ESMO Clinical Practice Guideline https://www.esmo.orgnull<p>This updated ESMO CPG provides diagnosis, staging, risk assessment, treatment and follow-up recommendations. It introduces new systemic treatments and innovative strategies, offering physicians practicing thoracic oncology advanced therapeutic options to improve outcomes and personalise care.</p>noreply@esmo.org8d7a31cc-4316-426c-9a9b-fe53dece6133Thu, 28 Aug 2025 08:08:00 +00:00 Superior EFS and OS in Patients with Nonmetastatic Osteosarcoma and Unfavourable Prognosis when Adjuvant Mifamurtide is Combined with High-Dose Ifosfamide https://www.esmo.orgnull<p>Findings from the ISG/OS-2 and GEIS-33 studies</p>noreply@esmo.org71f4b205-e613-44f8-86f1-e6b1afc68c9eThu, 28 Aug 2025 08:08:00 +00:00 Molecular Analysis for Precision Oncology Congress 2025, Paris, France, 15-16 September https://www.esmo.orgnull<p>The Molecular Analysis for Precision Oncology Congress 2025 (MAP) will bring together leading experts to explore the latest advances in cancer research, with a focus on deepening the understanding of disease mechanism and enhancing strategies for prevention and interception</p>noreply@esmo.org8b521c78-d705-426c-af80-d640aafdba56Wed, 27 Aug 2025 07:08:00 +00:00 Combining Enzalutamide with Radium-223 Significantly Improves rPFS as First-Line Therapy for Patients with mCRPC https://www.esmo.orgnull<p>Findings from the PEACE-3 study</p>noreply@esmo.orgf7879b8d-5c1c-4259-8f0d-efe16d428097Wed, 27 Aug 2025 07:08:00 +00:00 AI and remote monitoring are shaping a new patient journey in oncology https://www.esmo.orgnull<p>Real world experience suggests that the integration of digital tools into cancer care may close current gaps in patient outcomes reporting</p>noreply@esmo.org34da15a5-c125-47bd-b755-aa2474d72593Tue, 26 Aug 2025 22:08:00 +00:00 In Memory of Håkan Mellstedt: Former ESMO President https://www.esmo.orgnull<p>It is with deep sadness that ESMO has learnt of the passing of Professor Håkan Mellstedt, who died recently at the age of 82</p>noreply@esmo.org7dc6e2e0-2732-4ef0-852d-5cd9c71daf1bTue, 26 Aug 2025 12:08:00 +00:00 EMA Recommends Granting a Conditional Marketing Authorisation for Obecabtagene Autoleucel https://www.esmo.orgnull<p>It is intended for the treatment of adults from 26 years of age with relapsed or refractory B cell precursor ALL</p>noreply@esmo.orgb883a1ba-0478-438c-b5ad-b855cbfc0d09Tue, 26 Aug 2025 07:08:00 +00:00 Additional 5 Years of AI Treatment Reduces Distant Recurrence Rates Among Postmenopausal Women Already Treated with at Least 5 Years of Endocrine Therapy https://www.esmo.orgnull<p>Findings from a meta-analysis performed by the Early Breast Cancer Trialists' Collaborative Group</p>noreply@esmo.orgaae366ec-0676-4745-8c5a-f3417ecafa3eMon, 25 Aug 2025 07:08:00 +00:00 FDA Grants Accelerated Approval to Dordaviprone for Diffuse Midline Glioma https://www.esmo.orgnull<p>Evidence for efficacy is based on results from the ONC006, ONC013, ONC014, ONC016 and ONC018 studies</p>noreply@esmo.orga619a127-a1d6-4f54-96e8-4bdf3e567f21Fri, 22 Aug 2025 07:08:00 +00:00 Clinical Benefit and Genomic Features Associations Observed with Pembrolizumab Plus Axitinib in Patients with Advanced Clear Cell RCC https://www.esmo.orgnull<p>Findings from the KEYNOTE-426 study</p>noreply@esmo.org36cbe128-7def-4a17-9bd8-c253a9dfb8aaThu, 21 Aug 2025 07:08:00 +00:00 Adagrasib Improves PFS Over Docetaxel in Patients with Previously Treated KRASG12C-mutated NSCLC https://www.esmo.orgnull<p>Findings from the KRYSTAL-12 study</p>noreply@esmo.org8c65622a-b33b-4f13-8f22-12eb2c009b82Wed, 20 Aug 2025 07:08:00 +00:00 No Survival Benefit from Adding Adjuvant Chemotherapy to Endocrine Therapy in Older Women with a Genomic Grade Index High-Risk ER-positive, HER2-negative Breast Cancer https://www.esmo.orgnull<p>Findings from the ASTER 70s study</p>noreply@esmo.org2d825557-d2eb-4f7f-acb9-251237054d65Tue, 19 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Belantamab Mafodotin https://www.esmo.orgnull<p>It is intended for the treatment of patients with relapsed or refractory multiple myeloma</p>noreply@esmo.org965f5a4a-9a84-430c-bc6f-e40ca62558f5Mon, 18 Aug 2025 07:08:00 +00:00 ESMO Joins the European Health Alliance on Alcohol (EHAA) Seeking to Reduce Preventable Cancer Cases Linked to Alcohol Use https://www.esmo.orgnull<p>With alcohol consumption increasing the risk of developing at least 7 types of cancer, ESMO considers it crucial that robust policy action - at all political levels - is taken to effectively address the impact of alcohol-related harm on human health, thus enhancing cancer prevention</p>noreply@esmo.org796a42df-36fd-4a93-9ee2-41fa00b14ba2Thu, 14 Aug 2025 09:08:00 +00:00 CLDN18.2-Specific CAR T-Cell Therapy Prolongs PFS in Patients with Previously Treated Advanced Gastric or Gastro-oesophageal Junction Cancer https://www.esmo.orgnull<p>Findings from the CT041-ST-01 study</p>noreply@esmo.orgbebed821-c39b-48c2-bce8-7c5c96e4a8dbThu, 14 Aug 2025 07:08:00 +00:00 FDA Approves Tafasitamab-cxix for Relapsed or Refractory Follicular Lymphoma https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the inMIND study</p>noreply@esmo.org5e4115df-3e7b-4e40-bf32-d67663bd25ceThu, 14 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Vorasidenib https://www.esmo.orgnull<p>It is intended for the treatment of adults and adolescents with low grade astrocytoma or oligodendroglioma with an <em>IDH1</em> R132 or <em>IDH2</em> R172 mutation</p>noreply@esmo.org33595183-53c1-46d7-8d11-8efbe77ad103Wed, 13 Aug 2025 07:08:00 +00:00 Postoperative Radioiodine Can Be Avoided in Patients with Low-Risk Differentiated Thyroid Cancer https://www.esmo.orgnull<p>Findings from the IoN&nbsp;study</p>noreply@esmo.orgf44a7b22-946b-4057-90c0-b17c5d006568Tue, 12 Aug 2025 07:08:00 +00:00 ESMO Recommendations on Cancer Care Reflected in UN ECOSOC Ministerial Declaration on Sustainable Development https://www.esmo.orgnull<p>At the conclusion of the 2025 High-Level Political Forum (HLPF) on Sustainable Development, UN Member States adopted a Ministerial Declaration reaffirming commitment to universal health coverage (UHC), resilient health systems, and tackling non-communicable diseases (NCDs) like cancer</p>noreply@esmo.org1bac8e44-2826-4e2e-941a-7cda78fe8ffaMon, 11 Aug 2025 07:08:00 +00:00 ESMO Newshttps://www.esmo.org/The latest news from ESMOen-GBnoreply@esmo.org242, 30 Aug 2025 09:08:65 +00:00242, 30 Aug 2025 09:08:65 +00:00 FDA Grants Accelerated Approval to Zongertinib for Non-squamous NSCLC with HER2 Tyrosine Kinase Domain Activating Mutations https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the Beamion LUNG-1 study</p>noreply@esmo.orgbb0dc137-253d-4b77-929b-1beb77fa87e2Fri, 29 Aug 2025 08:08:00 +00:00 Early-Stage and Locally Advanced NSCLC: ESMO Clinical Practice Guideline https://www.esmo.orgnull<p>This updated ESMO CPG provides diagnosis, staging, risk assessment, treatment and follow-up recommendations. It introduces new systemic treatments and innovative strategies, offering physicians practicing thoracic oncology advanced therapeutic options to improve outcomes and personalise care.</p>noreply@esmo.org8d7a31cc-4316-426c-9a9b-fe53dece6133Thu, 28 Aug 2025 08:08:00 +00:00 Superior EFS and OS in Patients with Nonmetastatic Osteosarcoma and Unfavourable Prognosis when Adjuvant Mifamurtide is Combined with High-Dose Ifosfamide https://www.esmo.orgnull<p>Findings from the ISG/OS-2 and GEIS-33 studies</p>noreply@esmo.org71f4b205-e613-44f8-86f1-e6b1afc68c9eThu, 28 Aug 2025 08:08:00 +00:00 Molecular Analysis for Precision Oncology Congress 2025, Paris, France, 15-16 September https://www.esmo.orgnull<p>The Molecular Analysis for Precision Oncology Congress 2025 (MAP) will bring together leading experts to explore the latest advances in cancer research, with a focus on deepening the understanding of disease mechanism and enhancing strategies for prevention and interception</p>noreply@esmo.org8b521c78-d705-426c-af80-d640aafdba56Wed, 27 Aug 2025 07:08:00 +00:00 Combining Enzalutamide with Radium-223 Significantly Improves rPFS as First-Line Therapy for Patients with mCRPC https://www.esmo.orgnull<p>Findings from the PEACE-3 study</p>noreply@esmo.orgf7879b8d-5c1c-4259-8f0d-efe16d428097Wed, 27 Aug 2025 07:08:00 +00:00 AI and remote monitoring are shaping a new patient journey in oncology https://www.esmo.orgnull<p>Real world experience suggests that the integration of digital tools into cancer care may close current gaps in patient outcomes reporting</p>noreply@esmo.org34da15a5-c125-47bd-b755-aa2474d72593Tue, 26 Aug 2025 22:08:00 +00:00 In Memory of Håkan Mellstedt: Former ESMO President https://www.esmo.orgnull<p>It is with deep sadness that ESMO has learnt of the passing of Professor Håkan Mellstedt, who died recently at the age of 82</p>noreply@esmo.org7dc6e2e0-2732-4ef0-852d-5cd9c71daf1bTue, 26 Aug 2025 12:08:00 +00:00 EMA Recommends Granting a Conditional Marketing Authorisation for Obecabtagene Autoleucel https://www.esmo.orgnull<p>It is intended for the treatment of adults from 26 years of age with relapsed or refractory B cell precursor ALL</p>noreply@esmo.orgb883a1ba-0478-438c-b5ad-b855cbfc0d09Tue, 26 Aug 2025 07:08:00 +00:00 Additional 5 Years of AI Treatment Reduces Distant Recurrence Rates Among Postmenopausal Women Already Treated with at Least 5 Years of Endocrine Therapy https://www.esmo.orgnull<p>Findings from a meta-analysis performed by the Early Breast Cancer Trialists' Collaborative Group</p>noreply@esmo.orgaae366ec-0676-4745-8c5a-f3417ecafa3eMon, 25 Aug 2025 07:08:00 +00:00 FDA Grants Accelerated Approval to Dordaviprone for Diffuse Midline Glioma https://www.esmo.orgnull<p>Evidence for efficacy is based on results from the ONC006, ONC013, ONC014, ONC016 and ONC018 studies</p>noreply@esmo.orga619a127-a1d6-4f54-96e8-4bdf3e567f21Fri, 22 Aug 2025 07:08:00 +00:00 Clinical Benefit and Genomic Features Associations Observed with Pembrolizumab Plus Axitinib in Patients with Advanced Clear Cell RCC https://www.esmo.orgnull<p>Findings from the KEYNOTE-426 study</p>noreply@esmo.org36cbe128-7def-4a17-9bd8-c253a9dfb8aaThu, 21 Aug 2025 07:08:00 +00:00 Adagrasib Improves PFS Over Docetaxel in Patients with Previously Treated KRASG12C-mutated NSCLC https://www.esmo.orgnull<p>Findings from the KRYSTAL-12 study</p>noreply@esmo.org8c65622a-b33b-4f13-8f22-12eb2c009b82Wed, 20 Aug 2025 07:08:00 +00:00 No Survival Benefit from Adding Adjuvant Chemotherapy to Endocrine Therapy in Older Women with a Genomic Grade Index High-Risk ER-positive, HER2-negative Breast Cancer https://www.esmo.orgnull<p>Findings from the ASTER 70s study</p>noreply@esmo.org2d825557-d2eb-4f7f-acb9-251237054d65Tue, 19 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Belantamab Mafodotin https://www.esmo.orgnull<p>It is intended for the treatment of patients with relapsed or refractory multiple myeloma</p>noreply@esmo.org965f5a4a-9a84-430c-bc6f-e40ca62558f5Mon, 18 Aug 2025 07:08:00 +00:00 ESMO Joins the European Health Alliance on Alcohol (EHAA) Seeking to Reduce Preventable Cancer Cases Linked to Alcohol Use https://www.esmo.orgnull<p>With alcohol consumption increasing the risk of developing at least 7 types of cancer, ESMO considers it crucial that robust policy action - at all political levels - is taken to effectively address the impact of alcohol-related harm on human health, thus enhancing cancer prevention</p>noreply@esmo.org796a42df-36fd-4a93-9ee2-41fa00b14ba2Thu, 14 Aug 2025 09:08:00 +00:00 CLDN18.2-Specific CAR T-Cell Therapy Prolongs PFS in Patients with Previously Treated Advanced Gastric or Gastro-oesophageal Junction Cancer https://www.esmo.orgnull<p>Findings from the CT041-ST-01 study</p>noreply@esmo.orgbebed821-c39b-48c2-bce8-7c5c96e4a8dbThu, 14 Aug 2025 07:08:00 +00:00 FDA Approves Tafasitamab-cxix for Relapsed or Refractory Follicular Lymphoma https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the inMIND study</p>noreply@esmo.org5e4115df-3e7b-4e40-bf32-d67663bd25ceThu, 14 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Vorasidenib https://www.esmo.orgnull<p>It is intended for the treatment of adults and adolescents with low grade astrocytoma or oligodendroglioma with an <em>IDH1</em> R132 or <em>IDH2</em> R172 mutation</p>noreply@esmo.org33595183-53c1-46d7-8d11-8efbe77ad103Wed, 13 Aug 2025 07:08:00 +00:00 Postoperative Radioiodine Can Be Avoided in Patients with Low-Risk Differentiated Thyroid Cancer https://www.esmo.orgnull<p>Findings from the IoN&nbsp;study</p>noreply@esmo.orgf44a7b22-946b-4057-90c0-b17c5d006568Tue, 12 Aug 2025 07:08:00 +00:00 ESMO Recommendations on Cancer Care Reflected in UN ECOSOC Ministerial Declaration on Sustainable Development https://www.esmo.orgnull<p>At the conclusion of the 2025 High-Level Political Forum (HLPF) on Sustainable Development, UN Member States adopted a Ministerial Declaration reaffirming commitment to universal health coverage (UHC), resilient health systems, and tackling non-communicable diseases (NCDs) like cancer</p>noreply@esmo.org1bac8e44-2826-4e2e-941a-7cda78fe8ffaMon, 11 Aug 2025 07:08:00 +00:00 ESMO Newshttps://www.esmo.org/The latest news from ESMOen-GBnoreply@esmo.org242, 30 Aug 2025 09:08:22 +00:00242, 30 Aug 2025 09:08:22 +00:00 FDA Grants Accelerated Approval to Zongertinib for Non-squamous NSCLC with HER2 Tyrosine Kinase Domain Activating Mutations https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the Beamion LUNG-1 study</p>noreply@esmo.orgbb0dc137-253d-4b77-929b-1beb77fa87e2Fri, 29 Aug 2025 08:08:00 +00:00 Early-Stage and Locally Advanced NSCLC: ESMO Clinical Practice Guideline https://www.esmo.orgnull<p>This updated ESMO CPG provides diagnosis, staging, risk assessment, treatment and follow-up recommendations. It introduces new systemic treatments and innovative strategies, offering physicians practicing thoracic oncology advanced therapeutic options to improve outcomes and personalise care.</p>noreply@esmo.org8d7a31cc-4316-426c-9a9b-fe53dece6133Thu, 28 Aug 2025 08:08:00 +00:00 Superior EFS and OS in Patients with Nonmetastatic Osteosarcoma and Unfavourable Prognosis when Adjuvant Mifamurtide is Combined with High-Dose Ifosfamide https://www.esmo.orgnull<p>Findings from the ISG/OS-2 and GEIS-33 studies</p>noreply@esmo.org71f4b205-e613-44f8-86f1-e6b1afc68c9eThu, 28 Aug 2025 08:08:00 +00:00 Molecular Analysis for Precision Oncology Congress 2025, Paris, France, 15-16 September https://www.esmo.orgnull<p>The Molecular Analysis for Precision Oncology Congress 2025 (MAP) will bring together leading experts to explore the latest advances in cancer research, with a focus on deepening the understanding of disease mechanism and enhancing strategies for prevention and interception</p>noreply@esmo.org8b521c78-d705-426c-af80-d640aafdba56Wed, 27 Aug 2025 07:08:00 +00:00 Combining Enzalutamide with Radium-223 Significantly Improves rPFS as First-Line Therapy for Patients with mCRPC https://www.esmo.orgnull<p>Findings from the PEACE-3 study</p>noreply@esmo.orgf7879b8d-5c1c-4259-8f0d-efe16d428097Wed, 27 Aug 2025 07:08:00 +00:00 AI and remote monitoring are shaping a new patient journey in oncology https://www.esmo.orgnull<p>Real world experience suggests that the integration of digital tools into cancer care may close current gaps in patient outcomes reporting</p>noreply@esmo.org34da15a5-c125-47bd-b755-aa2474d72593Tue, 26 Aug 2025 22:08:00 +00:00 In Memory of Håkan Mellstedt: Former ESMO President https://www.esmo.orgnull<p>It is with deep sadness that ESMO has learnt of the passing of Professor Håkan Mellstedt, who died recently at the age of 82</p>noreply@esmo.org7dc6e2e0-2732-4ef0-852d-5cd9c71daf1bTue, 26 Aug 2025 12:08:00 +00:00 EMA Recommends Granting a Conditional Marketing Authorisation for Obecabtagene Autoleucel https://www.esmo.orgnull<p>It is intended for the treatment of adults from 26 years of age with relapsed or refractory B cell precursor ALL</p>noreply@esmo.orgb883a1ba-0478-438c-b5ad-b855cbfc0d09Tue, 26 Aug 2025 07:08:00 +00:00 Additional 5 Years of AI Treatment Reduces Distant Recurrence Rates Among Postmenopausal Women Already Treated with at Least 5 Years of Endocrine Therapy https://www.esmo.orgnull<p>Findings from a meta-analysis performed by the Early Breast Cancer Trialists' Collaborative Group</p>noreply@esmo.orgaae366ec-0676-4745-8c5a-f3417ecafa3eMon, 25 Aug 2025 07:08:00 +00:00 FDA Grants Accelerated Approval to Dordaviprone for Diffuse Midline Glioma https://www.esmo.orgnull<p>Evidence for efficacy is based on results from the ONC006, ONC013, ONC014, ONC016 and ONC018 studies</p>noreply@esmo.orga619a127-a1d6-4f54-96e8-4bdf3e567f21Fri, 22 Aug 2025 07:08:00 +00:00 Clinical Benefit and Genomic Features Associations Observed with Pembrolizumab Plus Axitinib in Patients with Advanced Clear Cell RCC https://www.esmo.orgnull<p>Findings from the KEYNOTE-426 study</p>noreply@esmo.org36cbe128-7def-4a17-9bd8-c253a9dfb8aaThu, 21 Aug 2025 07:08:00 +00:00 Adagrasib Improves PFS Over Docetaxel in Patients with Previously Treated KRASG12C-mutated NSCLC https://www.esmo.orgnull<p>Findings from the KRYSTAL-12 study</p>noreply@esmo.org8c65622a-b33b-4f13-8f22-12eb2c009b82Wed, 20 Aug 2025 07:08:00 +00:00 No Survival Benefit from Adding Adjuvant Chemotherapy to Endocrine Therapy in Older Women with a Genomic Grade Index High-Risk ER-positive, HER2-negative Breast Cancer https://www.esmo.orgnull<p>Findings from the ASTER 70s study</p>noreply@esmo.org2d825557-d2eb-4f7f-acb9-251237054d65Tue, 19 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Belantamab Mafodotin https://www.esmo.orgnull<p>It is intended for the treatment of patients with relapsed or refractory multiple myeloma</p>noreply@esmo.org965f5a4a-9a84-430c-bc6f-e40ca62558f5Mon, 18 Aug 2025 07:08:00 +00:00 ESMO Joins the European Health Alliance on Alcohol (EHAA) Seeking to Reduce Preventable Cancer Cases Linked to Alcohol Use https://www.esmo.orgnull<p>With alcohol consumption increasing the risk of developing at least 7 types of cancer, ESMO considers it crucial that robust policy action - at all political levels - is taken to effectively address the impact of alcohol-related harm on human health, thus enhancing cancer prevention</p>noreply@esmo.org796a42df-36fd-4a93-9ee2-41fa00b14ba2Thu, 14 Aug 2025 09:08:00 +00:00 CLDN18.2-Specific CAR T-Cell Therapy Prolongs PFS in Patients with Previously Treated Advanced Gastric or Gastro-oesophageal Junction Cancer https://www.esmo.orgnull<p>Findings from the CT041-ST-01 study</p>noreply@esmo.orgbebed821-c39b-48c2-bce8-7c5c96e4a8dbThu, 14 Aug 2025 07:08:00 +00:00 FDA Approves Tafasitamab-cxix for Relapsed or Refractory Follicular Lymphoma https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the inMIND study</p>noreply@esmo.org5e4115df-3e7b-4e40-bf32-d67663bd25ceThu, 14 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Vorasidenib https://www.esmo.orgnull<p>It is intended for the treatment of adults and adolescents with low grade astrocytoma or oligodendroglioma with an <em>IDH1</em> R132 or <em>IDH2</em> R172 mutation</p>noreply@esmo.org33595183-53c1-46d7-8d11-8efbe77ad103Wed, 13 Aug 2025 07:08:00 +00:00 Postoperative Radioiodine Can Be Avoided in Patients with Low-Risk Differentiated Thyroid Cancer https://www.esmo.orgnull<p>Findings from the IoN&nbsp;study</p>noreply@esmo.orgf44a7b22-946b-4057-90c0-b17c5d006568Tue, 12 Aug 2025 07:08:00 +00:00 ESMO Recommendations on Cancer Care Reflected in UN ECOSOC Ministerial Declaration on Sustainable Development https://www.esmo.orgnull<p>At the conclusion of the 2025 High-Level Political Forum (HLPF) on Sustainable Development, UN Member States adopted a Ministerial Declaration reaffirming commitment to universal health coverage (UHC), resilient health systems, and tackling non-communicable diseases (NCDs) like cancer</p>noreply@esmo.org1bac8e44-2826-4e2e-941a-7cda78fe8ffaMon, 11 Aug 2025 07:08:00 +00:00 ESMO Newshttps://www.esmo.org/The latest news from ESMOen-GBnoreply@esmo.org242, 30 Aug 2025 09:08:83 +00:00242, 30 Aug 2025 09:08:83 +00:00 FDA Grants Accelerated Approval to Zongertinib for Non-squamous NSCLC with HER2 Tyrosine Kinase Domain Activating Mutations https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the Beamion LUNG-1 study</p>noreply@esmo.orgbb0dc137-253d-4b77-929b-1beb77fa87e2Fri, 29 Aug 2025 08:08:00 +00:00 Early-Stage and Locally Advanced NSCLC: ESMO Clinical Practice Guideline https://www.esmo.orgnull<p>This updated ESMO CPG provides diagnosis, staging, risk assessment, treatment and follow-up recommendations. It introduces new systemic treatments and innovative strategies, offering physicians practicing thoracic oncology advanced therapeutic options to improve outcomes and personalise care.</p>noreply@esmo.org8d7a31cc-4316-426c-9a9b-fe53dece6133Thu, 28 Aug 2025 08:08:00 +00:00 Superior EFS and OS in Patients with Nonmetastatic Osteosarcoma and Unfavourable Prognosis when Adjuvant Mifamurtide is Combined with High-Dose Ifosfamide https://www.esmo.orgnull<p>Findings from the ISG/OS-2 and GEIS-33 studies</p>noreply@esmo.org71f4b205-e613-44f8-86f1-e6b1afc68c9eThu, 28 Aug 2025 08:08:00 +00:00 Molecular Analysis for Precision Oncology Congress 2025, Paris, France, 15-16 September https://www.esmo.orgnull<p>The Molecular Analysis for Precision Oncology Congress 2025 (MAP) will bring together leading experts to explore the latest advances in cancer research, with a focus on deepening the understanding of disease mechanism and enhancing strategies for prevention and interception</p>noreply@esmo.org8b521c78-d705-426c-af80-d640aafdba56Wed, 27 Aug 2025 07:08:00 +00:00 Combining Enzalutamide with Radium-223 Significantly Improves rPFS as First-Line Therapy for Patients with mCRPC https://www.esmo.orgnull<p>Findings from the PEACE-3 study</p>noreply@esmo.orgf7879b8d-5c1c-4259-8f0d-efe16d428097Wed, 27 Aug 2025 07:08:00 +00:00 AI and remote monitoring are shaping a new patient journey in oncology https://www.esmo.orgnull<p>Real world experience suggests that the integration of digital tools into cancer care may close current gaps in patient outcomes reporting</p>noreply@esmo.org34da15a5-c125-47bd-b755-aa2474d72593Tue, 26 Aug 2025 22:08:00 +00:00 In Memory of Håkan Mellstedt: Former ESMO President https://www.esmo.orgnull<p>It is with deep sadness that ESMO has learnt of the passing of Professor Håkan Mellstedt, who died recently at the age of 82</p>noreply@esmo.org7dc6e2e0-2732-4ef0-852d-5cd9c71daf1bTue, 26 Aug 2025 12:08:00 +00:00 EMA Recommends Granting a Conditional Marketing Authorisation for Obecabtagene Autoleucel https://www.esmo.orgnull<p>It is intended for the treatment of adults from 26 years of age with relapsed or refractory B cell precursor ALL</p>noreply@esmo.orgb883a1ba-0478-438c-b5ad-b855cbfc0d09Tue, 26 Aug 2025 07:08:00 +00:00 Additional 5 Years of AI Treatment Reduces Distant Recurrence Rates Among Postmenopausal Women Already Treated with at Least 5 Years of Endocrine Therapy https://www.esmo.orgnull<p>Findings from a meta-analysis performed by the Early Breast Cancer Trialists' Collaborative Group</p>noreply@esmo.orgaae366ec-0676-4745-8c5a-f3417ecafa3eMon, 25 Aug 2025 07:08:00 +00:00 FDA Grants Accelerated Approval to Dordaviprone for Diffuse Midline Glioma https://www.esmo.orgnull<p>Evidence for efficacy is based on results from the ONC006, ONC013, ONC014, ONC016 and ONC018 studies</p>noreply@esmo.orga619a127-a1d6-4f54-96e8-4bdf3e567f21Fri, 22 Aug 2025 07:08:00 +00:00 Clinical Benefit and Genomic Features Associations Observed with Pembrolizumab Plus Axitinib in Patients with Advanced Clear Cell RCC https://www.esmo.orgnull<p>Findings from the KEYNOTE-426 study</p>noreply@esmo.org36cbe128-7def-4a17-9bd8-c253a9dfb8aaThu, 21 Aug 2025 07:08:00 +00:00 Adagrasib Improves PFS Over Docetaxel in Patients with Previously Treated KRASG12C-mutated NSCLC https://www.esmo.orgnull<p>Findings from the KRYSTAL-12 study</p>noreply@esmo.org8c65622a-b33b-4f13-8f22-12eb2c009b82Wed, 20 Aug 2025 07:08:00 +00:00 No Survival Benefit from Adding Adjuvant Chemotherapy to Endocrine Therapy in Older Women with a Genomic Grade Index High-Risk ER-positive, HER2-negative Breast Cancer https://www.esmo.orgnull<p>Findings from the ASTER 70s study</p>noreply@esmo.org2d825557-d2eb-4f7f-acb9-251237054d65Tue, 19 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Belantamab Mafodotin https://www.esmo.orgnull<p>It is intended for the treatment of patients with relapsed or refractory multiple myeloma</p>noreply@esmo.org965f5a4a-9a84-430c-bc6f-e40ca62558f5Mon, 18 Aug 2025 07:08:00 +00:00 ESMO Joins the European Health Alliance on Alcohol (EHAA) Seeking to Reduce Preventable Cancer Cases Linked to Alcohol Use https://www.esmo.orgnull<p>With alcohol consumption increasing the risk of developing at least 7 types of cancer, ESMO considers it crucial that robust policy action - at all political levels - is taken to effectively address the impact of alcohol-related harm on human health, thus enhancing cancer prevention</p>noreply@esmo.org796a42df-36fd-4a93-9ee2-41fa00b14ba2Thu, 14 Aug 2025 09:08:00 +00:00 CLDN18.2-Specific CAR T-Cell Therapy Prolongs PFS in Patients with Previously Treated Advanced Gastric or Gastro-oesophageal Junction Cancer https://www.esmo.orgnull<p>Findings from the CT041-ST-01 study</p>noreply@esmo.orgbebed821-c39b-48c2-bce8-7c5c96e4a8dbThu, 14 Aug 2025 07:08:00 +00:00 FDA Approves Tafasitamab-cxix for Relapsed or Refractory Follicular Lymphoma https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the inMIND study</p>noreply@esmo.org5e4115df-3e7b-4e40-bf32-d67663bd25ceThu, 14 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Vorasidenib https://www.esmo.orgnull<p>It is intended for the treatment of adults and adolescents with low grade astrocytoma or oligodendroglioma with an <em>IDH1</em> R132 or <em>IDH2</em> R172 mutation</p>noreply@esmo.org33595183-53c1-46d7-8d11-8efbe77ad103Wed, 13 Aug 2025 07:08:00 +00:00 Postoperative Radioiodine Can Be Avoided in Patients with Low-Risk Differentiated Thyroid Cancer https://www.esmo.orgnull<p>Findings from the IoN&nbsp;study</p>noreply@esmo.orgf44a7b22-946b-4057-90c0-b17c5d006568Tue, 12 Aug 2025 07:08:00 +00:00 ESMO Recommendations on Cancer Care Reflected in UN ECOSOC Ministerial Declaration on Sustainable Development https://www.esmo.orgnull<p>At the conclusion of the 2025 High-Level Political Forum (HLPF) on Sustainable Development, UN Member States adopted a Ministerial Declaration reaffirming commitment to universal health coverage (UHC), resilient health systems, and tackling non-communicable diseases (NCDs) like cancer</p>noreply@esmo.org1bac8e44-2826-4e2e-941a-7cda78fe8ffaMon, 11 Aug 2025 07:08:00 +00:00 ESMO Newshttps://www.esmo.org/The latest news from ESMOen-GBnoreply@esmo.org242, 30 Aug 2025 09:08:74 +00:00242, 30 Aug 2025 09:08:74 +00:00 FDA Grants Accelerated Approval to Zongertinib for Non-squamous NSCLC with HER2 Tyrosine Kinase Domain Activating Mutations https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the Beamion LUNG-1 study</p>noreply@esmo.orgbb0dc137-253d-4b77-929b-1beb77fa87e2Fri, 29 Aug 2025 08:08:00 +00:00 Early-Stage and Locally Advanced NSCLC: ESMO Clinical Practice Guideline https://www.esmo.orgnull<p>This updated ESMO CPG provides diagnosis, staging, risk assessment, treatment and follow-up recommendations. It introduces new systemic treatments and innovative strategies, offering physicians practicing thoracic oncology advanced therapeutic options to improve outcomes and personalise care.</p>noreply@esmo.org8d7a31cc-4316-426c-9a9b-fe53dece6133Thu, 28 Aug 2025 08:08:00 +00:00 Superior EFS and OS in Patients with Nonmetastatic Osteosarcoma and Unfavourable Prognosis when Adjuvant Mifamurtide is Combined with High-Dose Ifosfamide https://www.esmo.orgnull<p>Findings from the ISG/OS-2 and GEIS-33 studies</p>noreply@esmo.org71f4b205-e613-44f8-86f1-e6b1afc68c9eThu, 28 Aug 2025 08:08:00 +00:00 Molecular Analysis for Precision Oncology Congress 2025, Paris, France, 15-16 September https://www.esmo.orgnull<p>The Molecular Analysis for Precision Oncology Congress 2025 (MAP) will bring together leading experts to explore the latest advances in cancer research, with a focus on deepening the understanding of disease mechanism and enhancing strategies for prevention and interception</p>noreply@esmo.org8b521c78-d705-426c-af80-d640aafdba56Wed, 27 Aug 2025 07:08:00 +00:00 Combining Enzalutamide with Radium-223 Significantly Improves rPFS as First-Line Therapy for Patients with mCRPC https://www.esmo.orgnull<p>Findings from the PEACE-3 study</p>noreply@esmo.orgf7879b8d-5c1c-4259-8f0d-efe16d428097Wed, 27 Aug 2025 07:08:00 +00:00 AI and remote monitoring are shaping a new patient journey in oncology https://www.esmo.orgnull<p>Real world experience suggests that the integration of digital tools into cancer care may close current gaps in patient outcomes reporting</p>noreply@esmo.org34da15a5-c125-47bd-b755-aa2474d72593Tue, 26 Aug 2025 22:08:00 +00:00 In Memory of Håkan Mellstedt: Former ESMO President https://www.esmo.orgnull<p>It is with deep sadness that ESMO has learnt of the passing of Professor Håkan Mellstedt, who died recently at the age of 82</p>noreply@esmo.org7dc6e2e0-2732-4ef0-852d-5cd9c71daf1bTue, 26 Aug 2025 12:08:00 +00:00 EMA Recommends Granting a Conditional Marketing Authorisation for Obecabtagene Autoleucel https://www.esmo.orgnull<p>It is intended for the treatment of adults from 26 years of age with relapsed or refractory B cell precursor ALL</p>noreply@esmo.orgb883a1ba-0478-438c-b5ad-b855cbfc0d09Tue, 26 Aug 2025 07:08:00 +00:00 Additional 5 Years of AI Treatment Reduces Distant Recurrence Rates Among Postmenopausal Women Already Treated with at Least 5 Years of Endocrine Therapy https://www.esmo.orgnull<p>Findings from a meta-analysis performed by the Early Breast Cancer Trialists' Collaborative Group</p>noreply@esmo.orgaae366ec-0676-4745-8c5a-f3417ecafa3eMon, 25 Aug 2025 07:08:00 +00:00 FDA Grants Accelerated Approval to Dordaviprone for Diffuse Midline Glioma https://www.esmo.orgnull<p>Evidence for efficacy is based on results from the ONC006, ONC013, ONC014, ONC016 and ONC018 studies</p>noreply@esmo.orga619a127-a1d6-4f54-96e8-4bdf3e567f21Fri, 22 Aug 2025 07:08:00 +00:00 Clinical Benefit and Genomic Features Associations Observed with Pembrolizumab Plus Axitinib in Patients with Advanced Clear Cell RCC https://www.esmo.orgnull<p>Findings from the KEYNOTE-426 study</p>noreply@esmo.org36cbe128-7def-4a17-9bd8-c253a9dfb8aaThu, 21 Aug 2025 07:08:00 +00:00 Adagrasib Improves PFS Over Docetaxel in Patients with Previously Treated KRASG12C-mutated NSCLC https://www.esmo.orgnull<p>Findings from the KRYSTAL-12 study</p>noreply@esmo.org8c65622a-b33b-4f13-8f22-12eb2c009b82Wed, 20 Aug 2025 07:08:00 +00:00 No Survival Benefit from Adding Adjuvant Chemotherapy to Endocrine Therapy in Older Women with a Genomic Grade Index High-Risk ER-positive, HER2-negative Breast Cancer https://www.esmo.orgnull<p>Findings from the ASTER 70s study</p>noreply@esmo.org2d825557-d2eb-4f7f-acb9-251237054d65Tue, 19 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Belantamab Mafodotin https://www.esmo.orgnull<p>It is intended for the treatment of patients with relapsed or refractory multiple myeloma</p>noreply@esmo.org965f5a4a-9a84-430c-bc6f-e40ca62558f5Mon, 18 Aug 2025 07:08:00 +00:00 ESMO Joins the European Health Alliance on Alcohol (EHAA) Seeking to Reduce Preventable Cancer Cases Linked to Alcohol Use https://www.esmo.orgnull<p>With alcohol consumption increasing the risk of developing at least 7 types of cancer, ESMO considers it crucial that robust policy action - at all political levels - is taken to effectively address the impact of alcohol-related harm on human health, thus enhancing cancer prevention</p>noreply@esmo.org796a42df-36fd-4a93-9ee2-41fa00b14ba2Thu, 14 Aug 2025 09:08:00 +00:00 CLDN18.2-Specific CAR T-Cell Therapy Prolongs PFS in Patients with Previously Treated Advanced Gastric or Gastro-oesophageal Junction Cancer https://www.esmo.orgnull<p>Findings from the CT041-ST-01 study</p>noreply@esmo.orgbebed821-c39b-48c2-bce8-7c5c96e4a8dbThu, 14 Aug 2025 07:08:00 +00:00 FDA Approves Tafasitamab-cxix for Relapsed or Refractory Follicular Lymphoma https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the inMIND study</p>noreply@esmo.org5e4115df-3e7b-4e40-bf32-d67663bd25ceThu, 14 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Vorasidenib https://www.esmo.orgnull<p>It is intended for the treatment of adults and adolescents with low grade astrocytoma or oligodendroglioma with an <em>IDH1</em> R132 or <em>IDH2</em> R172 mutation</p>noreply@esmo.org33595183-53c1-46d7-8d11-8efbe77ad103Wed, 13 Aug 2025 07:08:00 +00:00 Postoperative Radioiodine Can Be Avoided in Patients with Low-Risk Differentiated Thyroid Cancer https://www.esmo.orgnull<p>Findings from the IoN&nbsp;study</p>noreply@esmo.orgf44a7b22-946b-4057-90c0-b17c5d006568Tue, 12 Aug 2025 07:08:00 +00:00 ESMO Recommendations on Cancer Care Reflected in UN ECOSOC Ministerial Declaration on Sustainable Development https://www.esmo.orgnull<p>At the conclusion of the 2025 High-Level Political Forum (HLPF) on Sustainable Development, UN Member States adopted a Ministerial Declaration reaffirming commitment to universal health coverage (UHC), resilient health systems, and tackling non-communicable diseases (NCDs) like cancer</p>noreply@esmo.org1bac8e44-2826-4e2e-941a-7cda78fe8ffaMon, 11 Aug 2025 07:08:00 +00:00 ESMO Newshttps://www.esmo.org/The latest news from ESMOen-GBnoreply@esmo.org242, 30 Aug 2025 09:08:22 +00:00242, 30 Aug 2025 09:08:22 +00:00 FDA Grants Accelerated Approval to Zongertinib for Non-squamous NSCLC with HER2 Tyrosine Kinase Domain Activating Mutations https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the Beamion LUNG-1 study</p>noreply@esmo.orgbb0dc137-253d-4b77-929b-1beb77fa87e2Fri, 29 Aug 2025 08:08:00 +00:00 Early-Stage and Locally Advanced NSCLC: ESMO Clinical Practice Guideline https://www.esmo.orgnull<p>This updated ESMO CPG provides diagnosis, staging, risk assessment, treatment and follow-up recommendations. It introduces new systemic treatments and innovative strategies, offering physicians practicing thoracic oncology advanced therapeutic options to improve outcomes and personalise care.</p>noreply@esmo.org8d7a31cc-4316-426c-9a9b-fe53dece6133Thu, 28 Aug 2025 08:08:00 +00:00 Superior EFS and OS in Patients with Nonmetastatic Osteosarcoma and Unfavourable Prognosis when Adjuvant Mifamurtide is Combined with High-Dose Ifosfamide https://www.esmo.orgnull<p>Findings from the ISG/OS-2 and GEIS-33 studies</p>noreply@esmo.org71f4b205-e613-44f8-86f1-e6b1afc68c9eThu, 28 Aug 2025 08:08:00 +00:00 Molecular Analysis for Precision Oncology Congress 2025, Paris, France, 15-16 September https://www.esmo.orgnull<p>The Molecular Analysis for Precision Oncology Congress 2025 (MAP) will bring together leading experts to explore the latest advances in cancer research, with a focus on deepening the understanding of disease mechanism and enhancing strategies for prevention and interception</p>noreply@esmo.org8b521c78-d705-426c-af80-d640aafdba56Wed, 27 Aug 2025 07:08:00 +00:00 Combining Enzalutamide with Radium-223 Significantly Improves rPFS as First-Line Therapy for Patients with mCRPC https://www.esmo.orgnull<p>Findings from the PEACE-3 study</p>noreply@esmo.orgf7879b8d-5c1c-4259-8f0d-efe16d428097Wed, 27 Aug 2025 07:08:00 +00:00 AI and remote monitoring are shaping a new patient journey in oncology https://www.esmo.orgnull<p>Real world experience suggests that the integration of digital tools into cancer care may close current gaps in patient outcomes reporting</p>noreply@esmo.org34da15a5-c125-47bd-b755-aa2474d72593Tue, 26 Aug 2025 22:08:00 +00:00 In Memory of Håkan Mellstedt: Former ESMO President https://www.esmo.orgnull<p>It is with deep sadness that ESMO has learnt of the passing of Professor Håkan Mellstedt, who died recently at the age of 82</p>noreply@esmo.org7dc6e2e0-2732-4ef0-852d-5cd9c71daf1bTue, 26 Aug 2025 12:08:00 +00:00 EMA Recommends Granting a Conditional Marketing Authorisation for Obecabtagene Autoleucel https://www.esmo.orgnull<p>It is intended for the treatment of adults from 26 years of age with relapsed or refractory B cell precursor ALL</p>noreply@esmo.orgb883a1ba-0478-438c-b5ad-b855cbfc0d09Tue, 26 Aug 2025 07:08:00 +00:00 Additional 5 Years of AI Treatment Reduces Distant Recurrence Rates Among Postmenopausal Women Already Treated with at Least 5 Years of Endocrine Therapy https://www.esmo.orgnull<p>Findings from a meta-analysis performed by the Early Breast Cancer Trialists' Collaborative Group</p>noreply@esmo.orgaae366ec-0676-4745-8c5a-f3417ecafa3eMon, 25 Aug 2025 07:08:00 +00:00 FDA Grants Accelerated Approval to Dordaviprone for Diffuse Midline Glioma https://www.esmo.orgnull<p>Evidence for efficacy is based on results from the ONC006, ONC013, ONC014, ONC016 and ONC018 studies</p>noreply@esmo.orga619a127-a1d6-4f54-96e8-4bdf3e567f21Fri, 22 Aug 2025 07:08:00 +00:00 Clinical Benefit and Genomic Features Associations Observed with Pembrolizumab Plus Axitinib in Patients with Advanced Clear Cell RCC https://www.esmo.orgnull<p>Findings from the KEYNOTE-426 study</p>noreply@esmo.org36cbe128-7def-4a17-9bd8-c253a9dfb8aaThu, 21 Aug 2025 07:08:00 +00:00 Adagrasib Improves PFS Over Docetaxel in Patients with Previously Treated KRASG12C-mutated NSCLC https://www.esmo.orgnull<p>Findings from the KRYSTAL-12 study</p>noreply@esmo.org8c65622a-b33b-4f13-8f22-12eb2c009b82Wed, 20 Aug 2025 07:08:00 +00:00 No Survival Benefit from Adding Adjuvant Chemotherapy to Endocrine Therapy in Older Women with a Genomic Grade Index High-Risk ER-positive, HER2-negative Breast Cancer https://www.esmo.orgnull<p>Findings from the ASTER 70s study</p>noreply@esmo.org2d825557-d2eb-4f7f-acb9-251237054d65Tue, 19 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Belantamab Mafodotin https://www.esmo.orgnull<p>It is intended for the treatment of patients with relapsed or refractory multiple myeloma</p>noreply@esmo.org965f5a4a-9a84-430c-bc6f-e40ca62558f5Mon, 18 Aug 2025 07:08:00 +00:00 ESMO Joins the European Health Alliance on Alcohol (EHAA) Seeking to Reduce Preventable Cancer Cases Linked to Alcohol Use https://www.esmo.orgnull<p>With alcohol consumption increasing the risk of developing at least 7 types of cancer, ESMO considers it crucial that robust policy action - at all political levels - is taken to effectively address the impact of alcohol-related harm on human health, thus enhancing cancer prevention</p>noreply@esmo.org796a42df-36fd-4a93-9ee2-41fa00b14ba2Thu, 14 Aug 2025 09:08:00 +00:00 CLDN18.2-Specific CAR T-Cell Therapy Prolongs PFS in Patients with Previously Treated Advanced Gastric or Gastro-oesophageal Junction Cancer https://www.esmo.orgnull<p>Findings from the CT041-ST-01 study</p>noreply@esmo.orgbebed821-c39b-48c2-bce8-7c5c96e4a8dbThu, 14 Aug 2025 07:08:00 +00:00 FDA Approves Tafasitamab-cxix for Relapsed or Refractory Follicular Lymphoma https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the inMIND study</p>noreply@esmo.org5e4115df-3e7b-4e40-bf32-d67663bd25ceThu, 14 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Vorasidenib https://www.esmo.orgnull<p>It is intended for the treatment of adults and adolescents with low grade astrocytoma or oligodendroglioma with an <em>IDH1</em> R132 or <em>IDH2</em> R172 mutation</p>noreply@esmo.org33595183-53c1-46d7-8d11-8efbe77ad103Wed, 13 Aug 2025 07:08:00 +00:00 Postoperative Radioiodine Can Be Avoided in Patients with Low-Risk Differentiated Thyroid Cancer https://www.esmo.orgnull<p>Findings from the IoN&nbsp;study</p>noreply@esmo.orgf44a7b22-946b-4057-90c0-b17c5d006568Tue, 12 Aug 2025 07:08:00 +00:00 ESMO Recommendations on Cancer Care Reflected in UN ECOSOC Ministerial Declaration on Sustainable Development https://www.esmo.orgnull<p>At the conclusion of the 2025 High-Level Political Forum (HLPF) on Sustainable Development, UN Member States adopted a Ministerial Declaration reaffirming commitment to universal health coverage (UHC), resilient health systems, and tackling non-communicable diseases (NCDs) like cancer</p>noreply@esmo.org1bac8e44-2826-4e2e-941a-7cda78fe8ffaMon, 11 Aug 2025 07:08:00 +00:00 ESMO Newshttps://www.esmo.org/The latest news from ESMOen-GBnoreply@esmo.org242, 30 Aug 2025 09:08:50 +00:00242, 30 Aug 2025 09:08:50 +00:00 FDA Grants Accelerated Approval to Zongertinib for Non-squamous NSCLC with HER2 Tyrosine Kinase Domain Activating Mutations https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the Beamion LUNG-1 study</p>noreply@esmo.orgbb0dc137-253d-4b77-929b-1beb77fa87e2Fri, 29 Aug 2025 08:08:00 +00:00 Early-Stage and Locally Advanced NSCLC: ESMO Clinical Practice Guideline https://www.esmo.orgnull<p>This updated ESMO CPG provides diagnosis, staging, risk assessment, treatment and follow-up recommendations. It introduces new systemic treatments and innovative strategies, offering physicians practicing thoracic oncology advanced therapeutic options to improve outcomes and personalise care.</p>noreply@esmo.org8d7a31cc-4316-426c-9a9b-fe53dece6133Thu, 28 Aug 2025 08:08:00 +00:00 Superior EFS and OS in Patients with Nonmetastatic Osteosarcoma and Unfavourable Prognosis when Adjuvant Mifamurtide is Combined with High-Dose Ifosfamide https://www.esmo.orgnull<p>Findings from the ISG/OS-2 and GEIS-33 studies</p>noreply@esmo.org71f4b205-e613-44f8-86f1-e6b1afc68c9eThu, 28 Aug 2025 08:08:00 +00:00 Molecular Analysis for Precision Oncology Congress 2025, Paris, France, 15-16 September https://www.esmo.orgnull<p>The Molecular Analysis for Precision Oncology Congress 2025 (MAP) will bring together leading experts to explore the latest advances in cancer research, with a focus on deepening the understanding of disease mechanism and enhancing strategies for prevention and interception</p>noreply@esmo.org8b521c78-d705-426c-af80-d640aafdba56Wed, 27 Aug 2025 07:08:00 +00:00 Combining Enzalutamide with Radium-223 Significantly Improves rPFS as First-Line Therapy for Patients with mCRPC https://www.esmo.orgnull<p>Findings from the PEACE-3 study</p>noreply@esmo.orgf7879b8d-5c1c-4259-8f0d-efe16d428097Wed, 27 Aug 2025 07:08:00 +00:00 AI and remote monitoring are shaping a new patient journey in oncology https://www.esmo.orgnull<p>Real world experience suggests that the integration of digital tools into cancer care may close current gaps in patient outcomes reporting</p>noreply@esmo.org34da15a5-c125-47bd-b755-aa2474d72593Tue, 26 Aug 2025 22:08:00 +00:00 In Memory of Håkan Mellstedt: Former ESMO President https://www.esmo.orgnull<p>It is with deep sadness that ESMO has learnt of the passing of Professor Håkan Mellstedt, who died recently at the age of 82</p>noreply@esmo.org7dc6e2e0-2732-4ef0-852d-5cd9c71daf1bTue, 26 Aug 2025 12:08:00 +00:00 EMA Recommends Granting a Conditional Marketing Authorisation for Obecabtagene Autoleucel https://www.esmo.orgnull<p>It is intended for the treatment of adults from 26 years of age with relapsed or refractory B cell precursor ALL</p>noreply@esmo.orgb883a1ba-0478-438c-b5ad-b855cbfc0d09Tue, 26 Aug 2025 07:08:00 +00:00 Additional 5 Years of AI Treatment Reduces Distant Recurrence Rates Among Postmenopausal Women Already Treated with at Least 5 Years of Endocrine Therapy https://www.esmo.orgnull<p>Findings from a meta-analysis performed by the Early Breast Cancer Trialists' Collaborative Group</p>noreply@esmo.orgaae366ec-0676-4745-8c5a-f3417ecafa3eMon, 25 Aug 2025 07:08:00 +00:00 FDA Grants Accelerated Approval to Dordaviprone for Diffuse Midline Glioma https://www.esmo.orgnull<p>Evidence for efficacy is based on results from the ONC006, ONC013, ONC014, ONC016 and ONC018 studies</p>noreply@esmo.orga619a127-a1d6-4f54-96e8-4bdf3e567f21Fri, 22 Aug 2025 07:08:00 +00:00 Clinical Benefit and Genomic Features Associations Observed with Pembrolizumab Plus Axitinib in Patients with Advanced Clear Cell RCC https://www.esmo.orgnull<p>Findings from the KEYNOTE-426 study</p>noreply@esmo.org36cbe128-7def-4a17-9bd8-c253a9dfb8aaThu, 21 Aug 2025 07:08:00 +00:00 Adagrasib Improves PFS Over Docetaxel in Patients with Previously Treated KRASG12C-mutated NSCLC https://www.esmo.orgnull<p>Findings from the KRYSTAL-12 study</p>noreply@esmo.org8c65622a-b33b-4f13-8f22-12eb2c009b82Wed, 20 Aug 2025 07:08:00 +00:00 No Survival Benefit from Adding Adjuvant Chemotherapy to Endocrine Therapy in Older Women with a Genomic Grade Index High-Risk ER-positive, HER2-negative Breast Cancer https://www.esmo.orgnull<p>Findings from the ASTER 70s study</p>noreply@esmo.org2d825557-d2eb-4f7f-acb9-251237054d65Tue, 19 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Belantamab Mafodotin https://www.esmo.orgnull<p>It is intended for the treatment of patients with relapsed or refractory multiple myeloma</p>noreply@esmo.org965f5a4a-9a84-430c-bc6f-e40ca62558f5Mon, 18 Aug 2025 07:08:00 +00:00 ESMO Joins the European Health Alliance on Alcohol (EHAA) Seeking to Reduce Preventable Cancer Cases Linked to Alcohol Use https://www.esmo.orgnull<p>With alcohol consumption increasing the risk of developing at least 7 types of cancer, ESMO considers it crucial that robust policy action - at all political levels - is taken to effectively address the impact of alcohol-related harm on human health, thus enhancing cancer prevention</p>noreply@esmo.org796a42df-36fd-4a93-9ee2-41fa00b14ba2Thu, 14 Aug 2025 09:08:00 +00:00 CLDN18.2-Specific CAR T-Cell Therapy Prolongs PFS in Patients with Previously Treated Advanced Gastric or Gastro-oesophageal Junction Cancer https://www.esmo.orgnull<p>Findings from the CT041-ST-01 study</p>noreply@esmo.orgbebed821-c39b-48c2-bce8-7c5c96e4a8dbThu, 14 Aug 2025 07:08:00 +00:00 FDA Approves Tafasitamab-cxix for Relapsed or Refractory Follicular Lymphoma https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the inMIND study</p>noreply@esmo.org5e4115df-3e7b-4e40-bf32-d67663bd25ceThu, 14 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Vorasidenib https://www.esmo.orgnull<p>It is intended for the treatment of adults and adolescents with low grade astrocytoma or oligodendroglioma with an <em>IDH1</em> R132 or <em>IDH2</em> R172 mutation</p>noreply@esmo.org33595183-53c1-46d7-8d11-8efbe77ad103Wed, 13 Aug 2025 07:08:00 +00:00 Postoperative Radioiodine Can Be Avoided in Patients with Low-Risk Differentiated Thyroid Cancer https://www.esmo.orgnull<p>Findings from the IoN&nbsp;study</p>noreply@esmo.orgf44a7b22-946b-4057-90c0-b17c5d006568Tue, 12 Aug 2025 07:08:00 +00:00 ESMO Recommendations on Cancer Care Reflected in UN ECOSOC Ministerial Declaration on Sustainable Development https://www.esmo.orgnull<p>At the conclusion of the 2025 High-Level Political Forum (HLPF) on Sustainable Development, UN Member States adopted a Ministerial Declaration reaffirming commitment to universal health coverage (UHC), resilient health systems, and tackling non-communicable diseases (NCDs) like cancer</p>noreply@esmo.org1bac8e44-2826-4e2e-941a-7cda78fe8ffaMon, 11 Aug 2025 07:08:00 +00:00 ESMO Newshttps://www.esmo.org/The latest news from ESMOen-GBnoreply@esmo.org242, 30 Aug 2025 09:08:63 +00:00242, 30 Aug 2025 09:08:63 +00:00 FDA Grants Accelerated Approval to Zongertinib for Non-squamous NSCLC with HER2 Tyrosine Kinase Domain Activating Mutations https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the Beamion LUNG-1 study</p>noreply@esmo.orgbb0dc137-253d-4b77-929b-1beb77fa87e2Fri, 29 Aug 2025 08:08:00 +00:00 Early-Stage and Locally Advanced NSCLC: ESMO Clinical Practice Guideline https://www.esmo.orgnull<p>This updated ESMO CPG provides diagnosis, staging, risk assessment, treatment and follow-up recommendations. It introduces new systemic treatments and innovative strategies, offering physicians practicing thoracic oncology advanced therapeutic options to improve outcomes and personalise care.</p>noreply@esmo.org8d7a31cc-4316-426c-9a9b-fe53dece6133Thu, 28 Aug 2025 08:08:00 +00:00 Superior EFS and OS in Patients with Nonmetastatic Osteosarcoma and Unfavourable Prognosis when Adjuvant Mifamurtide is Combined with High-Dose Ifosfamide https://www.esmo.orgnull<p>Findings from the ISG/OS-2 and GEIS-33 studies</p>noreply@esmo.org71f4b205-e613-44f8-86f1-e6b1afc68c9eThu, 28 Aug 2025 08:08:00 +00:00 Molecular Analysis for Precision Oncology Congress 2025, Paris, France, 15-16 September https://www.esmo.orgnull<p>The Molecular Analysis for Precision Oncology Congress 2025 (MAP) will bring together leading experts to explore the latest advances in cancer research, with a focus on deepening the understanding of disease mechanism and enhancing strategies for prevention and interception</p>noreply@esmo.org8b521c78-d705-426c-af80-d640aafdba56Wed, 27 Aug 2025 07:08:00 +00:00 Combining Enzalutamide with Radium-223 Significantly Improves rPFS as First-Line Therapy for Patients with mCRPC https://www.esmo.orgnull<p>Findings from the PEACE-3 study</p>noreply@esmo.orgf7879b8d-5c1c-4259-8f0d-efe16d428097Wed, 27 Aug 2025 07:08:00 +00:00 AI and remote monitoring are shaping a new patient journey in oncology https://www.esmo.orgnull<p>Real world experience suggests that the integration of digital tools into cancer care may close current gaps in patient outcomes reporting</p>noreply@esmo.org34da15a5-c125-47bd-b755-aa2474d72593Tue, 26 Aug 2025 22:08:00 +00:00 In Memory of Håkan Mellstedt: Former ESMO President https://www.esmo.orgnull<p>It is with deep sadness that ESMO has learnt of the passing of Professor Håkan Mellstedt, who died recently at the age of 82</p>noreply@esmo.org7dc6e2e0-2732-4ef0-852d-5cd9c71daf1bTue, 26 Aug 2025 12:08:00 +00:00 EMA Recommends Granting a Conditional Marketing Authorisation for Obecabtagene Autoleucel https://www.esmo.orgnull<p>It is intended for the treatment of adults from 26 years of age with relapsed or refractory B cell precursor ALL</p>noreply@esmo.orgb883a1ba-0478-438c-b5ad-b855cbfc0d09Tue, 26 Aug 2025 07:08:00 +00:00 Additional 5 Years of AI Treatment Reduces Distant Recurrence Rates Among Postmenopausal Women Already Treated with at Least 5 Years of Endocrine Therapy https://www.esmo.orgnull<p>Findings from a meta-analysis performed by the Early Breast Cancer Trialists' Collaborative Group</p>noreply@esmo.orgaae366ec-0676-4745-8c5a-f3417ecafa3eMon, 25 Aug 2025 07:08:00 +00:00 FDA Grants Accelerated Approval to Dordaviprone for Diffuse Midline Glioma https://www.esmo.orgnull<p>Evidence for efficacy is based on results from the ONC006, ONC013, ONC014, ONC016 and ONC018 studies</p>noreply@esmo.orga619a127-a1d6-4f54-96e8-4bdf3e567f21Fri, 22 Aug 2025 07:08:00 +00:00 Clinical Benefit and Genomic Features Associations Observed with Pembrolizumab Plus Axitinib in Patients with Advanced Clear Cell RCC https://www.esmo.orgnull<p>Findings from the KEYNOTE-426 study</p>noreply@esmo.org36cbe128-7def-4a17-9bd8-c253a9dfb8aaThu, 21 Aug 2025 07:08:00 +00:00 Adagrasib Improves PFS Over Docetaxel in Patients with Previously Treated KRASG12C-mutated NSCLC https://www.esmo.orgnull<p>Findings from the KRYSTAL-12 study</p>noreply@esmo.org8c65622a-b33b-4f13-8f22-12eb2c009b82Wed, 20 Aug 2025 07:08:00 +00:00 No Survival Benefit from Adding Adjuvant Chemotherapy to Endocrine Therapy in Older Women with a Genomic Grade Index High-Risk ER-positive, HER2-negative Breast Cancer https://www.esmo.orgnull<p>Findings from the ASTER 70s study</p>noreply@esmo.org2d825557-d2eb-4f7f-acb9-251237054d65Tue, 19 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Belantamab Mafodotin https://www.esmo.orgnull<p>It is intended for the treatment of patients with relapsed or refractory multiple myeloma</p>noreply@esmo.org965f5a4a-9a84-430c-bc6f-e40ca62558f5Mon, 18 Aug 2025 07:08:00 +00:00 ESMO Joins the European Health Alliance on Alcohol (EHAA) Seeking to Reduce Preventable Cancer Cases Linked to Alcohol Use https://www.esmo.orgnull<p>With alcohol consumption increasing the risk of developing at least 7 types of cancer, ESMO considers it crucial that robust policy action - at all political levels - is taken to effectively address the impact of alcohol-related harm on human health, thus enhancing cancer prevention</p>noreply@esmo.org796a42df-36fd-4a93-9ee2-41fa00b14ba2Thu, 14 Aug 2025 09:08:00 +00:00 CLDN18.2-Specific CAR T-Cell Therapy Prolongs PFS in Patients with Previously Treated Advanced Gastric or Gastro-oesophageal Junction Cancer https://www.esmo.orgnull<p>Findings from the CT041-ST-01 study</p>noreply@esmo.orgbebed821-c39b-48c2-bce8-7c5c96e4a8dbThu, 14 Aug 2025 07:08:00 +00:00 FDA Approves Tafasitamab-cxix for Relapsed or Refractory Follicular Lymphoma https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the inMIND study</p>noreply@esmo.org5e4115df-3e7b-4e40-bf32-d67663bd25ceThu, 14 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Vorasidenib https://www.esmo.orgnull<p>It is intended for the treatment of adults and adolescents with low grade astrocytoma or oligodendroglioma with an <em>IDH1</em> R132 or <em>IDH2</em> R172 mutation</p>noreply@esmo.org33595183-53c1-46d7-8d11-8efbe77ad103Wed, 13 Aug 2025 07:08:00 +00:00 Postoperative Radioiodine Can Be Avoided in Patients with Low-Risk Differentiated Thyroid Cancer https://www.esmo.orgnull<p>Findings from the IoN&nbsp;study</p>noreply@esmo.orgf44a7b22-946b-4057-90c0-b17c5d006568Tue, 12 Aug 2025 07:08:00 +00:00 ESMO Recommendations on Cancer Care Reflected in UN ECOSOC Ministerial Declaration on Sustainable Development https://www.esmo.orgnull<p>At the conclusion of the 2025 High-Level Political Forum (HLPF) on Sustainable Development, UN Member States adopted a Ministerial Declaration reaffirming commitment to universal health coverage (UHC), resilient health systems, and tackling non-communicable diseases (NCDs) like cancer</p>noreply@esmo.org1bac8e44-2826-4e2e-941a-7cda78fe8ffaMon, 11 Aug 2025 07:08:00 +00:00 ESMO Newshttps://www.esmo.org/The latest news from ESMOen-GBnoreply@esmo.org242, 30 Aug 2025 09:08:88 +00:00242, 30 Aug 2025 09:08:88 +00:00 FDA Grants Accelerated Approval to Zongertinib for Non-squamous NSCLC with HER2 Tyrosine Kinase Domain Activating Mutations https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the Beamion LUNG-1 study</p>noreply@esmo.orgbb0dc137-253d-4b77-929b-1beb77fa87e2Fri, 29 Aug 2025 08:08:00 +00:00 Early-Stage and Locally Advanced NSCLC: ESMO Clinical Practice Guideline https://www.esmo.orgnull<p>This updated ESMO CPG provides diagnosis, staging, risk assessment, treatment and follow-up recommendations. It introduces new systemic treatments and innovative strategies, offering physicians practicing thoracic oncology advanced therapeutic options to improve outcomes and personalise care.</p>noreply@esmo.org8d7a31cc-4316-426c-9a9b-fe53dece6133Thu, 28 Aug 2025 08:08:00 +00:00 Superior EFS and OS in Patients with Nonmetastatic Osteosarcoma and Unfavourable Prognosis when Adjuvant Mifamurtide is Combined with High-Dose Ifosfamide https://www.esmo.orgnull<p>Findings from the ISG/OS-2 and GEIS-33 studies</p>noreply@esmo.org71f4b205-e613-44f8-86f1-e6b1afc68c9eThu, 28 Aug 2025 08:08:00 +00:00 Molecular Analysis for Precision Oncology Congress 2025, Paris, France, 15-16 September https://www.esmo.orgnull<p>The Molecular Analysis for Precision Oncology Congress 2025 (MAP) will bring together leading experts to explore the latest advances in cancer research, with a focus on deepening the understanding of disease mechanism and enhancing strategies for prevention and interception</p>noreply@esmo.org8b521c78-d705-426c-af80-d640aafdba56Wed, 27 Aug 2025 07:08:00 +00:00 Combining Enzalutamide with Radium-223 Significantly Improves rPFS as First-Line Therapy for Patients with mCRPC https://www.esmo.orgnull<p>Findings from the PEACE-3 study</p>noreply@esmo.orgf7879b8d-5c1c-4259-8f0d-efe16d428097Wed, 27 Aug 2025 07:08:00 +00:00 AI and remote monitoring are shaping a new patient journey in oncology https://www.esmo.orgnull<p>Real world experience suggests that the integration of digital tools into cancer care may close current gaps in patient outcomes reporting</p>noreply@esmo.org34da15a5-c125-47bd-b755-aa2474d72593Tue, 26 Aug 2025 22:08:00 +00:00 In Memory of Håkan Mellstedt: Former ESMO President https://www.esmo.orgnull<p>It is with deep sadness that ESMO has learnt of the passing of Professor Håkan Mellstedt, who died recently at the age of 82</p>noreply@esmo.org7dc6e2e0-2732-4ef0-852d-5cd9c71daf1bTue, 26 Aug 2025 12:08:00 +00:00 EMA Recommends Granting a Conditional Marketing Authorisation for Obecabtagene Autoleucel https://www.esmo.orgnull<p>It is intended for the treatment of adults from 26 years of age with relapsed or refractory B cell precursor ALL</p>noreply@esmo.orgb883a1ba-0478-438c-b5ad-b855cbfc0d09Tue, 26 Aug 2025 07:08:00 +00:00 Additional 5 Years of AI Treatment Reduces Distant Recurrence Rates Among Postmenopausal Women Already Treated with at Least 5 Years of Endocrine Therapy https://www.esmo.orgnull<p>Findings from a meta-analysis performed by the Early Breast Cancer Trialists' Collaborative Group</p>noreply@esmo.orgaae366ec-0676-4745-8c5a-f3417ecafa3eMon, 25 Aug 2025 07:08:00 +00:00 FDA Grants Accelerated Approval to Dordaviprone for Diffuse Midline Glioma https://www.esmo.orgnull<p>Evidence for efficacy is based on results from the ONC006, ONC013, ONC014, ONC016 and ONC018 studies</p>noreply@esmo.orga619a127-a1d6-4f54-96e8-4bdf3e567f21Fri, 22 Aug 2025 07:08:00 +00:00 Clinical Benefit and Genomic Features Associations Observed with Pembrolizumab Plus Axitinib in Patients with Advanced Clear Cell RCC https://www.esmo.orgnull<p>Findings from the KEYNOTE-426 study</p>noreply@esmo.org36cbe128-7def-4a17-9bd8-c253a9dfb8aaThu, 21 Aug 2025 07:08:00 +00:00 Adagrasib Improves PFS Over Docetaxel in Patients with Previously Treated KRASG12C-mutated NSCLC https://www.esmo.orgnull<p>Findings from the KRYSTAL-12 study</p>noreply@esmo.org8c65622a-b33b-4f13-8f22-12eb2c009b82Wed, 20 Aug 2025 07:08:00 +00:00 No Survival Benefit from Adding Adjuvant Chemotherapy to Endocrine Therapy in Older Women with a Genomic Grade Index High-Risk ER-positive, HER2-negative Breast Cancer https://www.esmo.orgnull<p>Findings from the ASTER 70s study</p>noreply@esmo.org2d825557-d2eb-4f7f-acb9-251237054d65Tue, 19 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Belantamab Mafodotin https://www.esmo.orgnull<p>It is intended for the treatment of patients with relapsed or refractory multiple myeloma</p>noreply@esmo.org965f5a4a-9a84-430c-bc6f-e40ca62558f5Mon, 18 Aug 2025 07:08:00 +00:00 ESMO Joins the European Health Alliance on Alcohol (EHAA) Seeking to Reduce Preventable Cancer Cases Linked to Alcohol Use https://www.esmo.orgnull<p>With alcohol consumption increasing the risk of developing at least 7 types of cancer, ESMO considers it crucial that robust policy action - at all political levels - is taken to effectively address the impact of alcohol-related harm on human health, thus enhancing cancer prevention</p>noreply@esmo.org796a42df-36fd-4a93-9ee2-41fa00b14ba2Thu, 14 Aug 2025 09:08:00 +00:00 CLDN18.2-Specific CAR T-Cell Therapy Prolongs PFS in Patients with Previously Treated Advanced Gastric or Gastro-oesophageal Junction Cancer https://www.esmo.orgnull<p>Findings from the CT041-ST-01 study</p>noreply@esmo.orgbebed821-c39b-48c2-bce8-7c5c96e4a8dbThu, 14 Aug 2025 07:08:00 +00:00 FDA Approves Tafasitamab-cxix for Relapsed or Refractory Follicular Lymphoma https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the inMIND study</p>noreply@esmo.org5e4115df-3e7b-4e40-bf32-d67663bd25ceThu, 14 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Vorasidenib https://www.esmo.orgnull<p>It is intended for the treatment of adults and adolescents with low grade astrocytoma or oligodendroglioma with an <em>IDH1</em> R132 or <em>IDH2</em> R172 mutation</p>noreply@esmo.org33595183-53c1-46d7-8d11-8efbe77ad103Wed, 13 Aug 2025 07:08:00 +00:00 Postoperative Radioiodine Can Be Avoided in Patients with Low-Risk Differentiated Thyroid Cancer https://www.esmo.orgnull<p>Findings from the IoN&nbsp;study</p>noreply@esmo.orgf44a7b22-946b-4057-90c0-b17c5d006568Tue, 12 Aug 2025 07:08:00 +00:00 ESMO Recommendations on Cancer Care Reflected in UN ECOSOC Ministerial Declaration on Sustainable Development https://www.esmo.orgnull<p>At the conclusion of the 2025 High-Level Political Forum (HLPF) on Sustainable Development, UN Member States adopted a Ministerial Declaration reaffirming commitment to universal health coverage (UHC), resilient health systems, and tackling non-communicable diseases (NCDs) like cancer</p>noreply@esmo.org1bac8e44-2826-4e2e-941a-7cda78fe8ffaMon, 11 Aug 2025 07:08:00 +00:00 ESMO Newshttps://www.esmo.org/The latest news from ESMOen-GBnoreply@esmo.org242, 30 Aug 2025 09:08:35 +00:00242, 30 Aug 2025 09:08:35 +00:00 FDA Grants Accelerated Approval to Zongertinib for Non-squamous NSCLC with HER2 Tyrosine Kinase Domain Activating Mutations https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the Beamion LUNG-1 study</p>noreply@esmo.orgbb0dc137-253d-4b77-929b-1beb77fa87e2Fri, 29 Aug 2025 08:08:00 +00:00 Early-Stage and Locally Advanced NSCLC: ESMO Clinical Practice Guideline https://www.esmo.orgnull<p>This updated ESMO CPG provides diagnosis, staging, risk assessment, treatment and follow-up recommendations. It introduces new systemic treatments and innovative strategies, offering physicians practicing thoracic oncology advanced therapeutic options to improve outcomes and personalise care.</p>noreply@esmo.org8d7a31cc-4316-426c-9a9b-fe53dece6133Thu, 28 Aug 2025 08:08:00 +00:00 Superior EFS and OS in Patients with Nonmetastatic Osteosarcoma and Unfavourable Prognosis when Adjuvant Mifamurtide is Combined with High-Dose Ifosfamide https://www.esmo.orgnull<p>Findings from the ISG/OS-2 and GEIS-33 studies</p>noreply@esmo.org71f4b205-e613-44f8-86f1-e6b1afc68c9eThu, 28 Aug 2025 08:08:00 +00:00 Molecular Analysis for Precision Oncology Congress 2025, Paris, France, 15-16 September https://www.esmo.orgnull<p>The Molecular Analysis for Precision Oncology Congress 2025 (MAP) will bring together leading experts to explore the latest advances in cancer research, with a focus on deepening the understanding of disease mechanism and enhancing strategies for prevention and interception</p>noreply@esmo.org8b521c78-d705-426c-af80-d640aafdba56Wed, 27 Aug 2025 07:08:00 +00:00 Combining Enzalutamide with Radium-223 Significantly Improves rPFS as First-Line Therapy for Patients with mCRPC https://www.esmo.orgnull<p>Findings from the PEACE-3 study</p>noreply@esmo.orgf7879b8d-5c1c-4259-8f0d-efe16d428097Wed, 27 Aug 2025 07:08:00 +00:00 AI and remote monitoring are shaping a new patient journey in oncology https://www.esmo.orgnull<p>Real world experience suggests that the integration of digital tools into cancer care may close current gaps in patient outcomes reporting</p>noreply@esmo.org34da15a5-c125-47bd-b755-aa2474d72593Tue, 26 Aug 2025 22:08:00 +00:00 In Memory of Håkan Mellstedt: Former ESMO President https://www.esmo.orgnull<p>It is with deep sadness that ESMO has learnt of the passing of Professor Håkan Mellstedt, who died recently at the age of 82</p>noreply@esmo.org7dc6e2e0-2732-4ef0-852d-5cd9c71daf1bTue, 26 Aug 2025 12:08:00 +00:00 EMA Recommends Granting a Conditional Marketing Authorisation for Obecabtagene Autoleucel https://www.esmo.orgnull<p>It is intended for the treatment of adults from 26 years of age with relapsed or refractory B cell precursor ALL</p>noreply@esmo.orgb883a1ba-0478-438c-b5ad-b855cbfc0d09Tue, 26 Aug 2025 07:08:00 +00:00 Additional 5 Years of AI Treatment Reduces Distant Recurrence Rates Among Postmenopausal Women Already Treated with at Least 5 Years of Endocrine Therapy https://www.esmo.orgnull<p>Findings from a meta-analysis performed by the Early Breast Cancer Trialists' Collaborative Group</p>noreply@esmo.orgaae366ec-0676-4745-8c5a-f3417ecafa3eMon, 25 Aug 2025 07:08:00 +00:00 FDA Grants Accelerated Approval to Dordaviprone for Diffuse Midline Glioma https://www.esmo.orgnull<p>Evidence for efficacy is based on results from the ONC006, ONC013, ONC014, ONC016 and ONC018 studies</p>noreply@esmo.orga619a127-a1d6-4f54-96e8-4bdf3e567f21Fri, 22 Aug 2025 07:08:00 +00:00 Clinical Benefit and Genomic Features Associations Observed with Pembrolizumab Plus Axitinib in Patients with Advanced Clear Cell RCC https://www.esmo.orgnull<p>Findings from the KEYNOTE-426 study</p>noreply@esmo.org36cbe128-7def-4a17-9bd8-c253a9dfb8aaThu, 21 Aug 2025 07:08:00 +00:00 Adagrasib Improves PFS Over Docetaxel in Patients with Previously Treated KRASG12C-mutated NSCLC https://www.esmo.orgnull<p>Findings from the KRYSTAL-12 study</p>noreply@esmo.org8c65622a-b33b-4f13-8f22-12eb2c009b82Wed, 20 Aug 2025 07:08:00 +00:00 No Survival Benefit from Adding Adjuvant Chemotherapy to Endocrine Therapy in Older Women with a Genomic Grade Index High-Risk ER-positive, HER2-negative Breast Cancer https://www.esmo.orgnull<p>Findings from the ASTER 70s study</p>noreply@esmo.org2d825557-d2eb-4f7f-acb9-251237054d65Tue, 19 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Belantamab Mafodotin https://www.esmo.orgnull<p>It is intended for the treatment of patients with relapsed or refractory multiple myeloma</p>noreply@esmo.org965f5a4a-9a84-430c-bc6f-e40ca62558f5Mon, 18 Aug 2025 07:08:00 +00:00 ESMO Joins the European Health Alliance on Alcohol (EHAA) Seeking to Reduce Preventable Cancer Cases Linked to Alcohol Use https://www.esmo.orgnull<p>With alcohol consumption increasing the risk of developing at least 7 types of cancer, ESMO considers it crucial that robust policy action - at all political levels - is taken to effectively address the impact of alcohol-related harm on human health, thus enhancing cancer prevention</p>noreply@esmo.org796a42df-36fd-4a93-9ee2-41fa00b14ba2Thu, 14 Aug 2025 09:08:00 +00:00 CLDN18.2-Specific CAR T-Cell Therapy Prolongs PFS in Patients with Previously Treated Advanced Gastric or Gastro-oesophageal Junction Cancer https://www.esmo.orgnull<p>Findings from the CT041-ST-01 study</p>noreply@esmo.orgbebed821-c39b-48c2-bce8-7c5c96e4a8dbThu, 14 Aug 2025 07:08:00 +00:00 FDA Approves Tafasitamab-cxix for Relapsed or Refractory Follicular Lymphoma https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the inMIND study</p>noreply@esmo.org5e4115df-3e7b-4e40-bf32-d67663bd25ceThu, 14 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Vorasidenib https://www.esmo.orgnull<p>It is intended for the treatment of adults and adolescents with low grade astrocytoma or oligodendroglioma with an <em>IDH1</em> R132 or <em>IDH2</em> R172 mutation</p>noreply@esmo.org33595183-53c1-46d7-8d11-8efbe77ad103Wed, 13 Aug 2025 07:08:00 +00:00 Postoperative Radioiodine Can Be Avoided in Patients with Low-Risk Differentiated Thyroid Cancer https://www.esmo.orgnull<p>Findings from the IoN&nbsp;study</p>noreply@esmo.orgf44a7b22-946b-4057-90c0-b17c5d006568Tue, 12 Aug 2025 07:08:00 +00:00 ESMO Recommendations on Cancer Care Reflected in UN ECOSOC Ministerial Declaration on Sustainable Development https://www.esmo.orgnull<p>At the conclusion of the 2025 High-Level Political Forum (HLPF) on Sustainable Development, UN Member States adopted a Ministerial Declaration reaffirming commitment to universal health coverage (UHC), resilient health systems, and tackling non-communicable diseases (NCDs) like cancer</p>noreply@esmo.org1bac8e44-2826-4e2e-941a-7cda78fe8ffaMon, 11 Aug 2025 07:08:00 +00:00 ESMO Newshttps://www.esmo.org/The latest news from ESMOen-GBnoreply@esmo.org242, 30 Aug 2025 09:08:34 +00:00242, 30 Aug 2025 09:08:34 +00:00 FDA Grants Accelerated Approval to Zongertinib for Non-squamous NSCLC with HER2 Tyrosine Kinase Domain Activating Mutations https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the Beamion LUNG-1 study</p>noreply@esmo.orgbb0dc137-253d-4b77-929b-1beb77fa87e2Fri, 29 Aug 2025 08:08:00 +00:00 Early-Stage and Locally Advanced NSCLC: ESMO Clinical Practice Guideline https://www.esmo.orgnull<p>This updated ESMO CPG provides diagnosis, staging, risk assessment, treatment and follow-up recommendations. It introduces new systemic treatments and innovative strategies, offering physicians practicing thoracic oncology advanced therapeutic options to improve outcomes and personalise care.</p>noreply@esmo.org8d7a31cc-4316-426c-9a9b-fe53dece6133Thu, 28 Aug 2025 08:08:00 +00:00 Superior EFS and OS in Patients with Nonmetastatic Osteosarcoma and Unfavourable Prognosis when Adjuvant Mifamurtide is Combined with High-Dose Ifosfamide https://www.esmo.orgnull<p>Findings from the ISG/OS-2 and GEIS-33 studies</p>noreply@esmo.org71f4b205-e613-44f8-86f1-e6b1afc68c9eThu, 28 Aug 2025 08:08:00 +00:00 Molecular Analysis for Precision Oncology Congress 2025, Paris, France, 15-16 September https://www.esmo.orgnull<p>The Molecular Analysis for Precision Oncology Congress 2025 (MAP) will bring together leading experts to explore the latest advances in cancer research, with a focus on deepening the understanding of disease mechanism and enhancing strategies for prevention and interception</p>noreply@esmo.org8b521c78-d705-426c-af80-d640aafdba56Wed, 27 Aug 2025 07:08:00 +00:00 Combining Enzalutamide with Radium-223 Significantly Improves rPFS as First-Line Therapy for Patients with mCRPC https://www.esmo.orgnull<p>Findings from the PEACE-3 study</p>noreply@esmo.orgf7879b8d-5c1c-4259-8f0d-efe16d428097Wed, 27 Aug 2025 07:08:00 +00:00 AI and remote monitoring are shaping a new patient journey in oncology https://www.esmo.orgnull<p>Real world experience suggests that the integration of digital tools into cancer care may close current gaps in patient outcomes reporting</p>noreply@esmo.org34da15a5-c125-47bd-b755-aa2474d72593Tue, 26 Aug 2025 22:08:00 +00:00 In Memory of Håkan Mellstedt: Former ESMO President https://www.esmo.orgnull<p>It is with deep sadness that ESMO has learnt of the passing of Professor Håkan Mellstedt, who died recently at the age of 82</p>noreply@esmo.org7dc6e2e0-2732-4ef0-852d-5cd9c71daf1bTue, 26 Aug 2025 12:08:00 +00:00 EMA Recommends Granting a Conditional Marketing Authorisation for Obecabtagene Autoleucel https://www.esmo.orgnull<p>It is intended for the treatment of adults from 26 years of age with relapsed or refractory B cell precursor ALL</p>noreply@esmo.orgb883a1ba-0478-438c-b5ad-b855cbfc0d09Tue, 26 Aug 2025 07:08:00 +00:00 Additional 5 Years of AI Treatment Reduces Distant Recurrence Rates Among Postmenopausal Women Already Treated with at Least 5 Years of Endocrine Therapy https://www.esmo.orgnull<p>Findings from a meta-analysis performed by the Early Breast Cancer Trialists' Collaborative Group</p>noreply@esmo.orgaae366ec-0676-4745-8c5a-f3417ecafa3eMon, 25 Aug 2025 07:08:00 +00:00 FDA Grants Accelerated Approval to Dordaviprone for Diffuse Midline Glioma https://www.esmo.orgnull<p>Evidence for efficacy is based on results from the ONC006, ONC013, ONC014, ONC016 and ONC018 studies</p>noreply@esmo.orga619a127-a1d6-4f54-96e8-4bdf3e567f21Fri, 22 Aug 2025 07:08:00 +00:00 Clinical Benefit and Genomic Features Associations Observed with Pembrolizumab Plus Axitinib in Patients with Advanced Clear Cell RCC https://www.esmo.orgnull<p>Findings from the KEYNOTE-426 study</p>noreply@esmo.org36cbe128-7def-4a17-9bd8-c253a9dfb8aaThu, 21 Aug 2025 07:08:00 +00:00 Adagrasib Improves PFS Over Docetaxel in Patients with Previously Treated KRASG12C-mutated NSCLC https://www.esmo.orgnull<p>Findings from the KRYSTAL-12 study</p>noreply@esmo.org8c65622a-b33b-4f13-8f22-12eb2c009b82Wed, 20 Aug 2025 07:08:00 +00:00 No Survival Benefit from Adding Adjuvant Chemotherapy to Endocrine Therapy in Older Women with a Genomic Grade Index High-Risk ER-positive, HER2-negative Breast Cancer https://www.esmo.orgnull<p>Findings from the ASTER 70s study</p>noreply@esmo.org2d825557-d2eb-4f7f-acb9-251237054d65Tue, 19 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Belantamab Mafodotin https://www.esmo.orgnull<p>It is intended for the treatment of patients with relapsed or refractory multiple myeloma</p>noreply@esmo.org965f5a4a-9a84-430c-bc6f-e40ca62558f5Mon, 18 Aug 2025 07:08:00 +00:00 ESMO Joins the European Health Alliance on Alcohol (EHAA) Seeking to Reduce Preventable Cancer Cases Linked to Alcohol Use https://www.esmo.orgnull<p>With alcohol consumption increasing the risk of developing at least 7 types of cancer, ESMO considers it crucial that robust policy action - at all political levels - is taken to effectively address the impact of alcohol-related harm on human health, thus enhancing cancer prevention</p>noreply@esmo.org796a42df-36fd-4a93-9ee2-41fa00b14ba2Thu, 14 Aug 2025 09:08:00 +00:00 CLDN18.2-Specific CAR T-Cell Therapy Prolongs PFS in Patients with Previously Treated Advanced Gastric or Gastro-oesophageal Junction Cancer https://www.esmo.orgnull<p>Findings from the CT041-ST-01 study</p>noreply@esmo.orgbebed821-c39b-48c2-bce8-7c5c96e4a8dbThu, 14 Aug 2025 07:08:00 +00:00 FDA Approves Tafasitamab-cxix for Relapsed or Refractory Follicular Lymphoma https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the inMIND study</p>noreply@esmo.org5e4115df-3e7b-4e40-bf32-d67663bd25ceThu, 14 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Vorasidenib https://www.esmo.orgnull<p>It is intended for the treatment of adults and adolescents with low grade astrocytoma or oligodendroglioma with an <em>IDH1</em> R132 or <em>IDH2</em> R172 mutation</p>noreply@esmo.org33595183-53c1-46d7-8d11-8efbe77ad103Wed, 13 Aug 2025 07:08:00 +00:00 Postoperative Radioiodine Can Be Avoided in Patients with Low-Risk Differentiated Thyroid Cancer https://www.esmo.orgnull<p>Findings from the IoN&nbsp;study</p>noreply@esmo.orgf44a7b22-946b-4057-90c0-b17c5d006568Tue, 12 Aug 2025 07:08:00 +00:00 ESMO Recommendations on Cancer Care Reflected in UN ECOSOC Ministerial Declaration on Sustainable Development https://www.esmo.orgnull<p>At the conclusion of the 2025 High-Level Political Forum (HLPF) on Sustainable Development, UN Member States adopted a Ministerial Declaration reaffirming commitment to universal health coverage (UHC), resilient health systems, and tackling non-communicable diseases (NCDs) like cancer</p>noreply@esmo.org1bac8e44-2826-4e2e-941a-7cda78fe8ffaMon, 11 Aug 2025 07:08:00 +00:00 ESMO Newshttps://www.esmo.org/The latest news from ESMOen-GBnoreply@esmo.org242, 30 Aug 2025 09:08:81 +00:00242, 30 Aug 2025 09:08:81 +00:00 FDA Grants Accelerated Approval to Zongertinib for Non-squamous NSCLC with HER2 Tyrosine Kinase Domain Activating Mutations https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the Beamion LUNG-1 study</p>noreply@esmo.orgbb0dc137-253d-4b77-929b-1beb77fa87e2Fri, 29 Aug 2025 08:08:00 +00:00 Early-Stage and Locally Advanced NSCLC: ESMO Clinical Practice Guideline https://www.esmo.orgnull<p>This updated ESMO CPG provides diagnosis, staging, risk assessment, treatment and follow-up recommendations. It introduces new systemic treatments and innovative strategies, offering physicians practicing thoracic oncology advanced therapeutic options to improve outcomes and personalise care.</p>noreply@esmo.org8d7a31cc-4316-426c-9a9b-fe53dece6133Thu, 28 Aug 2025 08:08:00 +00:00 Superior EFS and OS in Patients with Nonmetastatic Osteosarcoma and Unfavourable Prognosis when Adjuvant Mifamurtide is Combined with High-Dose Ifosfamide https://www.esmo.orgnull<p>Findings from the ISG/OS-2 and GEIS-33 studies</p>noreply@esmo.org71f4b205-e613-44f8-86f1-e6b1afc68c9eThu, 28 Aug 2025 08:08:00 +00:00 Molecular Analysis for Precision Oncology Congress 2025, Paris, France, 15-16 September https://www.esmo.orgnull<p>The Molecular Analysis for Precision Oncology Congress 2025 (MAP) will bring together leading experts to explore the latest advances in cancer research, with a focus on deepening the understanding of disease mechanism and enhancing strategies for prevention and interception</p>noreply@esmo.org8b521c78-d705-426c-af80-d640aafdba56Wed, 27 Aug 2025 07:08:00 +00:00 Combining Enzalutamide with Radium-223 Significantly Improves rPFS as First-Line Therapy for Patients with mCRPC https://www.esmo.orgnull<p>Findings from the PEACE-3 study</p>noreply@esmo.orgf7879b8d-5c1c-4259-8f0d-efe16d428097Wed, 27 Aug 2025 07:08:00 +00:00 AI and remote monitoring are shaping a new patient journey in oncology https://www.esmo.orgnull<p>Real world experience suggests that the integration of digital tools into cancer care may close current gaps in patient outcomes reporting</p>noreply@esmo.org34da15a5-c125-47bd-b755-aa2474d72593Tue, 26 Aug 2025 22:08:00 +00:00 In Memory of Håkan Mellstedt: Former ESMO President https://www.esmo.orgnull<p>It is with deep sadness that ESMO has learnt of the passing of Professor Håkan Mellstedt, who died recently at the age of 82</p>noreply@esmo.org7dc6e2e0-2732-4ef0-852d-5cd9c71daf1bTue, 26 Aug 2025 12:08:00 +00:00 EMA Recommends Granting a Conditional Marketing Authorisation for Obecabtagene Autoleucel https://www.esmo.orgnull<p>It is intended for the treatment of adults from 26 years of age with relapsed or refractory B cell precursor ALL</p>noreply@esmo.orgb883a1ba-0478-438c-b5ad-b855cbfc0d09Tue, 26 Aug 2025 07:08:00 +00:00 Additional 5 Years of AI Treatment Reduces Distant Recurrence Rates Among Postmenopausal Women Already Treated with at Least 5 Years of Endocrine Therapy https://www.esmo.orgnull<p>Findings from a meta-analysis performed by the Early Breast Cancer Trialists' Collaborative Group</p>noreply@esmo.orgaae366ec-0676-4745-8c5a-f3417ecafa3eMon, 25 Aug 2025 07:08:00 +00:00 FDA Grants Accelerated Approval to Dordaviprone for Diffuse Midline Glioma https://www.esmo.orgnull<p>Evidence for efficacy is based on results from the ONC006, ONC013, ONC014, ONC016 and ONC018 studies</p>noreply@esmo.orga619a127-a1d6-4f54-96e8-4bdf3e567f21Fri, 22 Aug 2025 07:08:00 +00:00 Clinical Benefit and Genomic Features Associations Observed with Pembrolizumab Plus Axitinib in Patients with Advanced Clear Cell RCC https://www.esmo.orgnull<p>Findings from the KEYNOTE-426 study</p>noreply@esmo.org36cbe128-7def-4a17-9bd8-c253a9dfb8aaThu, 21 Aug 2025 07:08:00 +00:00 Adagrasib Improves PFS Over Docetaxel in Patients with Previously Treated KRASG12C-mutated NSCLC https://www.esmo.orgnull<p>Findings from the KRYSTAL-12 study</p>noreply@esmo.org8c65622a-b33b-4f13-8f22-12eb2c009b82Wed, 20 Aug 2025 07:08:00 +00:00 No Survival Benefit from Adding Adjuvant Chemotherapy to Endocrine Therapy in Older Women with a Genomic Grade Index High-Risk ER-positive, HER2-negative Breast Cancer https://www.esmo.orgnull<p>Findings from the ASTER 70s study</p>noreply@esmo.org2d825557-d2eb-4f7f-acb9-251237054d65Tue, 19 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Belantamab Mafodotin https://www.esmo.orgnull<p>It is intended for the treatment of patients with relapsed or refractory multiple myeloma</p>noreply@esmo.org965f5a4a-9a84-430c-bc6f-e40ca62558f5Mon, 18 Aug 2025 07:08:00 +00:00 ESMO Joins the European Health Alliance on Alcohol (EHAA) Seeking to Reduce Preventable Cancer Cases Linked to Alcohol Use https://www.esmo.orgnull<p>With alcohol consumption increasing the risk of developing at least 7 types of cancer, ESMO considers it crucial that robust policy action - at all political levels - is taken to effectively address the impact of alcohol-related harm on human health, thus enhancing cancer prevention</p>noreply@esmo.org796a42df-36fd-4a93-9ee2-41fa00b14ba2Thu, 14 Aug 2025 09:08:00 +00:00 CLDN18.2-Specific CAR T-Cell Therapy Prolongs PFS in Patients with Previously Treated Advanced Gastric or Gastro-oesophageal Junction Cancer https://www.esmo.orgnull<p>Findings from the CT041-ST-01 study</p>noreply@esmo.orgbebed821-c39b-48c2-bce8-7c5c96e4a8dbThu, 14 Aug 2025 07:08:00 +00:00 FDA Approves Tafasitamab-cxix for Relapsed or Refractory Follicular Lymphoma https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the inMIND study</p>noreply@esmo.org5e4115df-3e7b-4e40-bf32-d67663bd25ceThu, 14 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Vorasidenib https://www.esmo.orgnull<p>It is intended for the treatment of adults and adolescents with low grade astrocytoma or oligodendroglioma with an <em>IDH1</em> R132 or <em>IDH2</em> R172 mutation</p>noreply@esmo.org33595183-53c1-46d7-8d11-8efbe77ad103Wed, 13 Aug 2025 07:08:00 +00:00 Postoperative Radioiodine Can Be Avoided in Patients with Low-Risk Differentiated Thyroid Cancer https://www.esmo.orgnull<p>Findings from the IoN&nbsp;study</p>noreply@esmo.orgf44a7b22-946b-4057-90c0-b17c5d006568Tue, 12 Aug 2025 07:08:00 +00:00 ESMO Recommendations on Cancer Care Reflected in UN ECOSOC Ministerial Declaration on Sustainable Development https://www.esmo.orgnull<p>At the conclusion of the 2025 High-Level Political Forum (HLPF) on Sustainable Development, UN Member States adopted a Ministerial Declaration reaffirming commitment to universal health coverage (UHC), resilient health systems, and tackling non-communicable diseases (NCDs) like cancer</p>noreply@esmo.org1bac8e44-2826-4e2e-941a-7cda78fe8ffaMon, 11 Aug 2025 07:08:00 +00:00 ESMO Newshttps://www.esmo.org/The latest news from ESMOen-GBnoreply@esmo.org242, 30 Aug 2025 09:08:58 +00:00242, 30 Aug 2025 09:08:58 +00:00 FDA Grants Accelerated Approval to Zongertinib for Non-squamous NSCLC with HER2 Tyrosine Kinase Domain Activating Mutations https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the Beamion LUNG-1 study</p>noreply@esmo.orgbb0dc137-253d-4b77-929b-1beb77fa87e2Fri, 29 Aug 2025 08:08:00 +00:00 Early-Stage and Locally Advanced NSCLC: ESMO Clinical Practice Guideline https://www.esmo.orgnull<p>This updated ESMO CPG provides diagnosis, staging, risk assessment, treatment and follow-up recommendations. It introduces new systemic treatments and innovative strategies, offering physicians practicing thoracic oncology advanced therapeutic options to improve outcomes and personalise care.</p>noreply@esmo.org8d7a31cc-4316-426c-9a9b-fe53dece6133Thu, 28 Aug 2025 08:08:00 +00:00 Superior EFS and OS in Patients with Nonmetastatic Osteosarcoma and Unfavourable Prognosis when Adjuvant Mifamurtide is Combined with High-Dose Ifosfamide https://www.esmo.orgnull<p>Findings from the ISG/OS-2 and GEIS-33 studies</p>noreply@esmo.org71f4b205-e613-44f8-86f1-e6b1afc68c9eThu, 28 Aug 2025 08:08:00 +00:00 Molecular Analysis for Precision Oncology Congress 2025, Paris, France, 15-16 September https://www.esmo.orgnull<p>The Molecular Analysis for Precision Oncology Congress 2025 (MAP) will bring together leading experts to explore the latest advances in cancer research, with a focus on deepening the understanding of disease mechanism and enhancing strategies for prevention and interception</p>noreply@esmo.org8b521c78-d705-426c-af80-d640aafdba56Wed, 27 Aug 2025 07:08:00 +00:00 Combining Enzalutamide with Radium-223 Significantly Improves rPFS as First-Line Therapy for Patients with mCRPC https://www.esmo.orgnull<p>Findings from the PEACE-3 study</p>noreply@esmo.orgf7879b8d-5c1c-4259-8f0d-efe16d428097Wed, 27 Aug 2025 07:08:00 +00:00 AI and remote monitoring are shaping a new patient journey in oncology https://www.esmo.orgnull<p>Real world experience suggests that the integration of digital tools into cancer care may close current gaps in patient outcomes reporting</p>noreply@esmo.org34da15a5-c125-47bd-b755-aa2474d72593Tue, 26 Aug 2025 22:08:00 +00:00 In Memory of Håkan Mellstedt: Former ESMO President https://www.esmo.orgnull<p>It is with deep sadness that ESMO has learnt of the passing of Professor Håkan Mellstedt, who died recently at the age of 82</p>noreply@esmo.org7dc6e2e0-2732-4ef0-852d-5cd9c71daf1bTue, 26 Aug 2025 12:08:00 +00:00 EMA Recommends Granting a Conditional Marketing Authorisation for Obecabtagene Autoleucel https://www.esmo.orgnull<p>It is intended for the treatment of adults from 26 years of age with relapsed or refractory B cell precursor ALL</p>noreply@esmo.orgb883a1ba-0478-438c-b5ad-b855cbfc0d09Tue, 26 Aug 2025 07:08:00 +00:00 Additional 5 Years of AI Treatment Reduces Distant Recurrence Rates Among Postmenopausal Women Already Treated with at Least 5 Years of Endocrine Therapy https://www.esmo.orgnull<p>Findings from a meta-analysis performed by the Early Breast Cancer Trialists' Collaborative Group</p>noreply@esmo.orgaae366ec-0676-4745-8c5a-f3417ecafa3eMon, 25 Aug 2025 07:08:00 +00:00 FDA Grants Accelerated Approval to Dordaviprone for Diffuse Midline Glioma https://www.esmo.orgnull<p>Evidence for efficacy is based on results from the ONC006, ONC013, ONC014, ONC016 and ONC018 studies</p>noreply@esmo.orga619a127-a1d6-4f54-96e8-4bdf3e567f21Fri, 22 Aug 2025 07:08:00 +00:00 Clinical Benefit and Genomic Features Associations Observed with Pembrolizumab Plus Axitinib in Patients with Advanced Clear Cell RCC https://www.esmo.orgnull<p>Findings from the KEYNOTE-426 study</p>noreply@esmo.org36cbe128-7def-4a17-9bd8-c253a9dfb8aaThu, 21 Aug 2025 07:08:00 +00:00 Adagrasib Improves PFS Over Docetaxel in Patients with Previously Treated KRASG12C-mutated NSCLC https://www.esmo.orgnull<p>Findings from the KRYSTAL-12 study</p>noreply@esmo.org8c65622a-b33b-4f13-8f22-12eb2c009b82Wed, 20 Aug 2025 07:08:00 +00:00 No Survival Benefit from Adding Adjuvant Chemotherapy to Endocrine Therapy in Older Women with a Genomic Grade Index High-Risk ER-positive, HER2-negative Breast Cancer https://www.esmo.orgnull<p>Findings from the ASTER 70s study</p>noreply@esmo.org2d825557-d2eb-4f7f-acb9-251237054d65Tue, 19 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Belantamab Mafodotin https://www.esmo.orgnull<p>It is intended for the treatment of patients with relapsed or refractory multiple myeloma</p>noreply@esmo.org965f5a4a-9a84-430c-bc6f-e40ca62558f5Mon, 18 Aug 2025 07:08:00 +00:00 ESMO Joins the European Health Alliance on Alcohol (EHAA) Seeking to Reduce Preventable Cancer Cases Linked to Alcohol Use https://www.esmo.orgnull<p>With alcohol consumption increasing the risk of developing at least 7 types of cancer, ESMO considers it crucial that robust policy action - at all political levels - is taken to effectively address the impact of alcohol-related harm on human health, thus enhancing cancer prevention</p>noreply@esmo.org796a42df-36fd-4a93-9ee2-41fa00b14ba2Thu, 14 Aug 2025 09:08:00 +00:00 CLDN18.2-Specific CAR T-Cell Therapy Prolongs PFS in Patients with Previously Treated Advanced Gastric or Gastro-oesophageal Junction Cancer https://www.esmo.orgnull<p>Findings from the CT041-ST-01 study</p>noreply@esmo.orgbebed821-c39b-48c2-bce8-7c5c96e4a8dbThu, 14 Aug 2025 07:08:00 +00:00 FDA Approves Tafasitamab-cxix for Relapsed or Refractory Follicular Lymphoma https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the inMIND study</p>noreply@esmo.org5e4115df-3e7b-4e40-bf32-d67663bd25ceThu, 14 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Vorasidenib https://www.esmo.orgnull<p>It is intended for the treatment of adults and adolescents with low grade astrocytoma or oligodendroglioma with an <em>IDH1</em> R132 or <em>IDH2</em> R172 mutation</p>noreply@esmo.org33595183-53c1-46d7-8d11-8efbe77ad103Wed, 13 Aug 2025 07:08:00 +00:00 Postoperative Radioiodine Can Be Avoided in Patients with Low-Risk Differentiated Thyroid Cancer https://www.esmo.orgnull<p>Findings from the IoN&nbsp;study</p>noreply@esmo.orgf44a7b22-946b-4057-90c0-b17c5d006568Tue, 12 Aug 2025 07:08:00 +00:00 ESMO Recommendations on Cancer Care Reflected in UN ECOSOC Ministerial Declaration on Sustainable Development https://www.esmo.orgnull<p>At the conclusion of the 2025 High-Level Political Forum (HLPF) on Sustainable Development, UN Member States adopted a Ministerial Declaration reaffirming commitment to universal health coverage (UHC), resilient health systems, and tackling non-communicable diseases (NCDs) like cancer</p>noreply@esmo.org1bac8e44-2826-4e2e-941a-7cda78fe8ffaMon, 11 Aug 2025 07:08:00 +00:00 ESMO Newshttps://www.esmo.org/The latest news from ESMOen-GBnoreply@esmo.org242, 30 Aug 2025 09:08:01 +00:00242, 30 Aug 2025 09:08:01 +00:00 FDA Grants Accelerated Approval to Zongertinib for Non-squamous NSCLC with HER2 Tyrosine Kinase Domain Activating Mutations https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the Beamion LUNG-1 study</p>noreply@esmo.orgbb0dc137-253d-4b77-929b-1beb77fa87e2Fri, 29 Aug 2025 08:08:00 +00:00 Early-Stage and Locally Advanced NSCLC: ESMO Clinical Practice Guideline https://www.esmo.orgnull<p>This updated ESMO CPG provides diagnosis, staging, risk assessment, treatment and follow-up recommendations. It introduces new systemic treatments and innovative strategies, offering physicians practicing thoracic oncology advanced therapeutic options to improve outcomes and personalise care.</p>noreply@esmo.org8d7a31cc-4316-426c-9a9b-fe53dece6133Thu, 28 Aug 2025 08:08:00 +00:00 Superior EFS and OS in Patients with Nonmetastatic Osteosarcoma and Unfavourable Prognosis when Adjuvant Mifamurtide is Combined with High-Dose Ifosfamide https://www.esmo.orgnull<p>Findings from the ISG/OS-2 and GEIS-33 studies</p>noreply@esmo.org71f4b205-e613-44f8-86f1-e6b1afc68c9eThu, 28 Aug 2025 08:08:00 +00:00 Molecular Analysis for Precision Oncology Congress 2025, Paris, France, 15-16 September https://www.esmo.orgnull<p>The Molecular Analysis for Precision Oncology Congress 2025 (MAP) will bring together leading experts to explore the latest advances in cancer research, with a focus on deepening the understanding of disease mechanism and enhancing strategies for prevention and interception</p>noreply@esmo.org8b521c78-d705-426c-af80-d640aafdba56Wed, 27 Aug 2025 07:08:00 +00:00 Combining Enzalutamide with Radium-223 Significantly Improves rPFS as First-Line Therapy for Patients with mCRPC https://www.esmo.orgnull<p>Findings from the PEACE-3 study</p>noreply@esmo.orgf7879b8d-5c1c-4259-8f0d-efe16d428097Wed, 27 Aug 2025 07:08:00 +00:00 AI and remote monitoring are shaping a new patient journey in oncology https://www.esmo.orgnull<p>Real world experience suggests that the integration of digital tools into cancer care may close current gaps in patient outcomes reporting</p>noreply@esmo.org34da15a5-c125-47bd-b755-aa2474d72593Tue, 26 Aug 2025 22:08:00 +00:00 In Memory of Håkan Mellstedt: Former ESMO President https://www.esmo.orgnull<p>It is with deep sadness that ESMO has learnt of the passing of Professor Håkan Mellstedt, who died recently at the age of 82</p>noreply@esmo.org7dc6e2e0-2732-4ef0-852d-5cd9c71daf1bTue, 26 Aug 2025 12:08:00 +00:00 EMA Recommends Granting a Conditional Marketing Authorisation for Obecabtagene Autoleucel https://www.esmo.orgnull<p>It is intended for the treatment of adults from 26 years of age with relapsed or refractory B cell precursor ALL</p>noreply@esmo.orgb883a1ba-0478-438c-b5ad-b855cbfc0d09Tue, 26 Aug 2025 07:08:00 +00:00 Additional 5 Years of AI Treatment Reduces Distant Recurrence Rates Among Postmenopausal Women Already Treated with at Least 5 Years of Endocrine Therapy https://www.esmo.orgnull<p>Findings from a meta-analysis performed by the Early Breast Cancer Trialists' Collaborative Group</p>noreply@esmo.orgaae366ec-0676-4745-8c5a-f3417ecafa3eMon, 25 Aug 2025 07:08:00 +00:00 FDA Grants Accelerated Approval to Dordaviprone for Diffuse Midline Glioma https://www.esmo.orgnull<p>Evidence for efficacy is based on results from the ONC006, ONC013, ONC014, ONC016 and ONC018 studies</p>noreply@esmo.orga619a127-a1d6-4f54-96e8-4bdf3e567f21Fri, 22 Aug 2025 07:08:00 +00:00 Clinical Benefit and Genomic Features Associations Observed with Pembrolizumab Plus Axitinib in Patients with Advanced Clear Cell RCC https://www.esmo.orgnull<p>Findings from the KEYNOTE-426 study</p>noreply@esmo.org36cbe128-7def-4a17-9bd8-c253a9dfb8aaThu, 21 Aug 2025 07:08:00 +00:00 Adagrasib Improves PFS Over Docetaxel in Patients with Previously Treated KRASG12C-mutated NSCLC https://www.esmo.orgnull<p>Findings from the KRYSTAL-12 study</p>noreply@esmo.org8c65622a-b33b-4f13-8f22-12eb2c009b82Wed, 20 Aug 2025 07:08:00 +00:00 No Survival Benefit from Adding Adjuvant Chemotherapy to Endocrine Therapy in Older Women with a Genomic Grade Index High-Risk ER-positive, HER2-negative Breast Cancer https://www.esmo.orgnull<p>Findings from the ASTER 70s study</p>noreply@esmo.org2d825557-d2eb-4f7f-acb9-251237054d65Tue, 19 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Belantamab Mafodotin https://www.esmo.orgnull<p>It is intended for the treatment of patients with relapsed or refractory multiple myeloma</p>noreply@esmo.org965f5a4a-9a84-430c-bc6f-e40ca62558f5Mon, 18 Aug 2025 07:08:00 +00:00 ESMO Joins the European Health Alliance on Alcohol (EHAA) Seeking to Reduce Preventable Cancer Cases Linked to Alcohol Use https://www.esmo.orgnull<p>With alcohol consumption increasing the risk of developing at least 7 types of cancer, ESMO considers it crucial that robust policy action - at all political levels - is taken to effectively address the impact of alcohol-related harm on human health, thus enhancing cancer prevention</p>noreply@esmo.org796a42df-36fd-4a93-9ee2-41fa00b14ba2Thu, 14 Aug 2025 09:08:00 +00:00 CLDN18.2-Specific CAR T-Cell Therapy Prolongs PFS in Patients with Previously Treated Advanced Gastric or Gastro-oesophageal Junction Cancer https://www.esmo.orgnull<p>Findings from the CT041-ST-01 study</p>noreply@esmo.orgbebed821-c39b-48c2-bce8-7c5c96e4a8dbThu, 14 Aug 2025 07:08:00 +00:00 FDA Approves Tafasitamab-cxix for Relapsed or Refractory Follicular Lymphoma https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the inMIND study</p>noreply@esmo.org5e4115df-3e7b-4e40-bf32-d67663bd25ceThu, 14 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Vorasidenib https://www.esmo.orgnull<p>It is intended for the treatment of adults and adolescents with low grade astrocytoma or oligodendroglioma with an <em>IDH1</em> R132 or <em>IDH2</em> R172 mutation</p>noreply@esmo.org33595183-53c1-46d7-8d11-8efbe77ad103Wed, 13 Aug 2025 07:08:00 +00:00 Postoperative Radioiodine Can Be Avoided in Patients with Low-Risk Differentiated Thyroid Cancer https://www.esmo.orgnull<p>Findings from the IoN&nbsp;study</p>noreply@esmo.orgf44a7b22-946b-4057-90c0-b17c5d006568Tue, 12 Aug 2025 07:08:00 +00:00 ESMO Recommendations on Cancer Care Reflected in UN ECOSOC Ministerial Declaration on Sustainable Development https://www.esmo.orgnull<p>At the conclusion of the 2025 High-Level Political Forum (HLPF) on Sustainable Development, UN Member States adopted a Ministerial Declaration reaffirming commitment to universal health coverage (UHC), resilient health systems, and tackling non-communicable diseases (NCDs) like cancer</p>noreply@esmo.org1bac8e44-2826-4e2e-941a-7cda78fe8ffaMon, 11 Aug 2025 07:08:00 +00:00 ESMO Newshttps://www.esmo.org/The latest news from ESMOen-GBnoreply@esmo.org242, 30 Aug 2025 09:08:12 +00:00242, 30 Aug 2025 09:08:12 +00:00 FDA Grants Accelerated Approval to Zongertinib for Non-squamous NSCLC with HER2 Tyrosine Kinase Domain Activating Mutations https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the Beamion LUNG-1 study</p>noreply@esmo.orgbb0dc137-253d-4b77-929b-1beb77fa87e2Fri, 29 Aug 2025 08:08:00 +00:00 Early-Stage and Locally Advanced NSCLC: ESMO Clinical Practice Guideline https://www.esmo.orgnull<p>This updated ESMO CPG provides diagnosis, staging, risk assessment, treatment and follow-up recommendations. It introduces new systemic treatments and innovative strategies, offering physicians practicing thoracic oncology advanced therapeutic options to improve outcomes and personalise care.</p>noreply@esmo.org8d7a31cc-4316-426c-9a9b-fe53dece6133Thu, 28 Aug 2025 08:08:00 +00:00 Superior EFS and OS in Patients with Nonmetastatic Osteosarcoma and Unfavourable Prognosis when Adjuvant Mifamurtide is Combined with High-Dose Ifosfamide https://www.esmo.orgnull<p>Findings from the ISG/OS-2 and GEIS-33 studies</p>noreply@esmo.org71f4b205-e613-44f8-86f1-e6b1afc68c9eThu, 28 Aug 2025 08:08:00 +00:00 Molecular Analysis for Precision Oncology Congress 2025, Paris, France, 15-16 September https://www.esmo.orgnull<p>The Molecular Analysis for Precision Oncology Congress 2025 (MAP) will bring together leading experts to explore the latest advances in cancer research, with a focus on deepening the understanding of disease mechanism and enhancing strategies for prevention and interception</p>noreply@esmo.org8b521c78-d705-426c-af80-d640aafdba56Wed, 27 Aug 2025 07:08:00 +00:00 Combining Enzalutamide with Radium-223 Significantly Improves rPFS as First-Line Therapy for Patients with mCRPC https://www.esmo.orgnull<p>Findings from the PEACE-3 study</p>noreply@esmo.orgf7879b8d-5c1c-4259-8f0d-efe16d428097Wed, 27 Aug 2025 07:08:00 +00:00 AI and remote monitoring are shaping a new patient journey in oncology https://www.esmo.orgnull<p>Real world experience suggests that the integration of digital tools into cancer care may close current gaps in patient outcomes reporting</p>noreply@esmo.org34da15a5-c125-47bd-b755-aa2474d72593Tue, 26 Aug 2025 22:08:00 +00:00 In Memory of Håkan Mellstedt: Former ESMO President https://www.esmo.orgnull<p>It is with deep sadness that ESMO has learnt of the passing of Professor Håkan Mellstedt, who died recently at the age of 82</p>noreply@esmo.org7dc6e2e0-2732-4ef0-852d-5cd9c71daf1bTue, 26 Aug 2025 12:08:00 +00:00 EMA Recommends Granting a Conditional Marketing Authorisation for Obecabtagene Autoleucel https://www.esmo.orgnull<p>It is intended for the treatment of adults from 26 years of age with relapsed or refractory B cell precursor ALL</p>noreply@esmo.orgb883a1ba-0478-438c-b5ad-b855cbfc0d09Tue, 26 Aug 2025 07:08:00 +00:00 Additional 5 Years of AI Treatment Reduces Distant Recurrence Rates Among Postmenopausal Women Already Treated with at Least 5 Years of Endocrine Therapy https://www.esmo.orgnull<p>Findings from a meta-analysis performed by the Early Breast Cancer Trialists' Collaborative Group</p>noreply@esmo.orgaae366ec-0676-4745-8c5a-f3417ecafa3eMon, 25 Aug 2025 07:08:00 +00:00 FDA Grants Accelerated Approval to Dordaviprone for Diffuse Midline Glioma https://www.esmo.orgnull<p>Evidence for efficacy is based on results from the ONC006, ONC013, ONC014, ONC016 and ONC018 studies</p>noreply@esmo.orga619a127-a1d6-4f54-96e8-4bdf3e567f21Fri, 22 Aug 2025 07:08:00 +00:00 Clinical Benefit and Genomic Features Associations Observed with Pembrolizumab Plus Axitinib in Patients with Advanced Clear Cell RCC https://www.esmo.orgnull<p>Findings from the KEYNOTE-426 study</p>noreply@esmo.org36cbe128-7def-4a17-9bd8-c253a9dfb8aaThu, 21 Aug 2025 07:08:00 +00:00 Adagrasib Improves PFS Over Docetaxel in Patients with Previously Treated KRASG12C-mutated NSCLC https://www.esmo.orgnull<p>Findings from the KRYSTAL-12 study</p>noreply@esmo.org8c65622a-b33b-4f13-8f22-12eb2c009b82Wed, 20 Aug 2025 07:08:00 +00:00 No Survival Benefit from Adding Adjuvant Chemotherapy to Endocrine Therapy in Older Women with a Genomic Grade Index High-Risk ER-positive, HER2-negative Breast Cancer https://www.esmo.orgnull<p>Findings from the ASTER 70s study</p>noreply@esmo.org2d825557-d2eb-4f7f-acb9-251237054d65Tue, 19 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Belantamab Mafodotin https://www.esmo.orgnull<p>It is intended for the treatment of patients with relapsed or refractory multiple myeloma</p>noreply@esmo.org965f5a4a-9a84-430c-bc6f-e40ca62558f5Mon, 18 Aug 2025 07:08:00 +00:00 ESMO Joins the European Health Alliance on Alcohol (EHAA) Seeking to Reduce Preventable Cancer Cases Linked to Alcohol Use https://www.esmo.orgnull<p>With alcohol consumption increasing the risk of developing at least 7 types of cancer, ESMO considers it crucial that robust policy action - at all political levels - is taken to effectively address the impact of alcohol-related harm on human health, thus enhancing cancer prevention</p>noreply@esmo.org796a42df-36fd-4a93-9ee2-41fa00b14ba2Thu, 14 Aug 2025 09:08:00 +00:00 CLDN18.2-Specific CAR T-Cell Therapy Prolongs PFS in Patients with Previously Treated Advanced Gastric or Gastro-oesophageal Junction Cancer https://www.esmo.orgnull<p>Findings from the CT041-ST-01 study</p>noreply@esmo.orgbebed821-c39b-48c2-bce8-7c5c96e4a8dbThu, 14 Aug 2025 07:08:00 +00:00 FDA Approves Tafasitamab-cxix for Relapsed or Refractory Follicular Lymphoma https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the inMIND study</p>noreply@esmo.org5e4115df-3e7b-4e40-bf32-d67663bd25ceThu, 14 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Vorasidenib https://www.esmo.orgnull<p>It is intended for the treatment of adults and adolescents with low grade astrocytoma or oligodendroglioma with an <em>IDH1</em> R132 or <em>IDH2</em> R172 mutation</p>noreply@esmo.org33595183-53c1-46d7-8d11-8efbe77ad103Wed, 13 Aug 2025 07:08:00 +00:00 Postoperative Radioiodine Can Be Avoided in Patients with Low-Risk Differentiated Thyroid Cancer https://www.esmo.orgnull<p>Findings from the IoN&nbsp;study</p>noreply@esmo.orgf44a7b22-946b-4057-90c0-b17c5d006568Tue, 12 Aug 2025 07:08:00 +00:00 ESMO Recommendations on Cancer Care Reflected in UN ECOSOC Ministerial Declaration on Sustainable Development https://www.esmo.orgnull<p>At the conclusion of the 2025 High-Level Political Forum (HLPF) on Sustainable Development, UN Member States adopted a Ministerial Declaration reaffirming commitment to universal health coverage (UHC), resilient health systems, and tackling non-communicable diseases (NCDs) like cancer</p>noreply@esmo.org1bac8e44-2826-4e2e-941a-7cda78fe8ffaMon, 11 Aug 2025 07:08:00 +00:00 ESMO Newshttps://www.esmo.org/The latest news from ESMOen-GBnoreply@esmo.org242, 30 Aug 2025 09:08:44 +00:00242, 30 Aug 2025 09:08:44 +00:00 FDA Grants Accelerated Approval to Zongertinib for Non-squamous NSCLC with HER2 Tyrosine Kinase Domain Activating Mutations https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the Beamion LUNG-1 study</p>noreply@esmo.orgbb0dc137-253d-4b77-929b-1beb77fa87e2Fri, 29 Aug 2025 08:08:00 +00:00 Early-Stage and Locally Advanced NSCLC: ESMO Clinical Practice Guideline https://www.esmo.orgnull<p>This updated ESMO CPG provides diagnosis, staging, risk assessment, treatment and follow-up recommendations. It introduces new systemic treatments and innovative strategies, offering physicians practicing thoracic oncology advanced therapeutic options to improve outcomes and personalise care.</p>noreply@esmo.org8d7a31cc-4316-426c-9a9b-fe53dece6133Thu, 28 Aug 2025 08:08:00 +00:00 Superior EFS and OS in Patients with Nonmetastatic Osteosarcoma and Unfavourable Prognosis when Adjuvant Mifamurtide is Combined with High-Dose Ifosfamide https://www.esmo.orgnull<p>Findings from the ISG/OS-2 and GEIS-33 studies</p>noreply@esmo.org71f4b205-e613-44f8-86f1-e6b1afc68c9eThu, 28 Aug 2025 08:08:00 +00:00 Molecular Analysis for Precision Oncology Congress 2025, Paris, France, 15-16 September https://www.esmo.orgnull<p>The Molecular Analysis for Precision Oncology Congress 2025 (MAP) will bring together leading experts to explore the latest advances in cancer research, with a focus on deepening the understanding of disease mechanism and enhancing strategies for prevention and interception</p>noreply@esmo.org8b521c78-d705-426c-af80-d640aafdba56Wed, 27 Aug 2025 07:08:00 +00:00 Combining Enzalutamide with Radium-223 Significantly Improves rPFS as First-Line Therapy for Patients with mCRPC https://www.esmo.orgnull<p>Findings from the PEACE-3 study</p>noreply@esmo.orgf7879b8d-5c1c-4259-8f0d-efe16d428097Wed, 27 Aug 2025 07:08:00 +00:00 AI and remote monitoring are shaping a new patient journey in oncology https://www.esmo.orgnull<p>Real world experience suggests that the integration of digital tools into cancer care may close current gaps in patient outcomes reporting</p>noreply@esmo.org34da15a5-c125-47bd-b755-aa2474d72593Tue, 26 Aug 2025 22:08:00 +00:00 In Memory of Håkan Mellstedt: Former ESMO President https://www.esmo.orgnull<p>It is with deep sadness that ESMO has learnt of the passing of Professor Håkan Mellstedt, who died recently at the age of 82</p>noreply@esmo.org7dc6e2e0-2732-4ef0-852d-5cd9c71daf1bTue, 26 Aug 2025 12:08:00 +00:00 EMA Recommends Granting a Conditional Marketing Authorisation for Obecabtagene Autoleucel https://www.esmo.orgnull<p>It is intended for the treatment of adults from 26 years of age with relapsed or refractory B cell precursor ALL</p>noreply@esmo.orgb883a1ba-0478-438c-b5ad-b855cbfc0d09Tue, 26 Aug 2025 07:08:00 +00:00 Additional 5 Years of AI Treatment Reduces Distant Recurrence Rates Among Postmenopausal Women Already Treated with at Least 5 Years of Endocrine Therapy https://www.esmo.orgnull<p>Findings from a meta-analysis performed by the Early Breast Cancer Trialists' Collaborative Group</p>noreply@esmo.orgaae366ec-0676-4745-8c5a-f3417ecafa3eMon, 25 Aug 2025 07:08:00 +00:00 FDA Grants Accelerated Approval to Dordaviprone for Diffuse Midline Glioma https://www.esmo.orgnull<p>Evidence for efficacy is based on results from the ONC006, ONC013, ONC014, ONC016 and ONC018 studies</p>noreply@esmo.orga619a127-a1d6-4f54-96e8-4bdf3e567f21Fri, 22 Aug 2025 07:08:00 +00:00 Clinical Benefit and Genomic Features Associations Observed with Pembrolizumab Plus Axitinib in Patients with Advanced Clear Cell RCC https://www.esmo.orgnull<p>Findings from the KEYNOTE-426 study</p>noreply@esmo.org36cbe128-7def-4a17-9bd8-c253a9dfb8aaThu, 21 Aug 2025 07:08:00 +00:00 Adagrasib Improves PFS Over Docetaxel in Patients with Previously Treated KRASG12C-mutated NSCLC https://www.esmo.orgnull<p>Findings from the KRYSTAL-12 study</p>noreply@esmo.org8c65622a-b33b-4f13-8f22-12eb2c009b82Wed, 20 Aug 2025 07:08:00 +00:00 No Survival Benefit from Adding Adjuvant Chemotherapy to Endocrine Therapy in Older Women with a Genomic Grade Index High-Risk ER-positive, HER2-negative Breast Cancer https://www.esmo.orgnull<p>Findings from the ASTER 70s study</p>noreply@esmo.org2d825557-d2eb-4f7f-acb9-251237054d65Tue, 19 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Belantamab Mafodotin https://www.esmo.orgnull<p>It is intended for the treatment of patients with relapsed or refractory multiple myeloma</p>noreply@esmo.org965f5a4a-9a84-430c-bc6f-e40ca62558f5Mon, 18 Aug 2025 07:08:00 +00:00 ESMO Joins the European Health Alliance on Alcohol (EHAA) Seeking to Reduce Preventable Cancer Cases Linked to Alcohol Use https://www.esmo.orgnull<p>With alcohol consumption increasing the risk of developing at least 7 types of cancer, ESMO considers it crucial that robust policy action - at all political levels - is taken to effectively address the impact of alcohol-related harm on human health, thus enhancing cancer prevention</p>noreply@esmo.org796a42df-36fd-4a93-9ee2-41fa00b14ba2Thu, 14 Aug 2025 09:08:00 +00:00 CLDN18.2-Specific CAR T-Cell Therapy Prolongs PFS in Patients with Previously Treated Advanced Gastric or Gastro-oesophageal Junction Cancer https://www.esmo.orgnull<p>Findings from the CT041-ST-01 study</p>noreply@esmo.orgbebed821-c39b-48c2-bce8-7c5c96e4a8dbThu, 14 Aug 2025 07:08:00 +00:00 FDA Approves Tafasitamab-cxix for Relapsed or Refractory Follicular Lymphoma https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the inMIND study</p>noreply@esmo.org5e4115df-3e7b-4e40-bf32-d67663bd25ceThu, 14 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Vorasidenib https://www.esmo.orgnull<p>It is intended for the treatment of adults and adolescents with low grade astrocytoma or oligodendroglioma with an <em>IDH1</em> R132 or <em>IDH2</em> R172 mutation</p>noreply@esmo.org33595183-53c1-46d7-8d11-8efbe77ad103Wed, 13 Aug 2025 07:08:00 +00:00 Postoperative Radioiodine Can Be Avoided in Patients with Low-Risk Differentiated Thyroid Cancer https://www.esmo.orgnull<p>Findings from the IoN&nbsp;study</p>noreply@esmo.orgf44a7b22-946b-4057-90c0-b17c5d006568Tue, 12 Aug 2025 07:08:00 +00:00 ESMO Recommendations on Cancer Care Reflected in UN ECOSOC Ministerial Declaration on Sustainable Development https://www.esmo.orgnull<p>At the conclusion of the 2025 High-Level Political Forum (HLPF) on Sustainable Development, UN Member States adopted a Ministerial Declaration reaffirming commitment to universal health coverage (UHC), resilient health systems, and tackling non-communicable diseases (NCDs) like cancer</p>noreply@esmo.org1bac8e44-2826-4e2e-941a-7cda78fe8ffaMon, 11 Aug 2025 07:08:00 +00:00 ESMO Newshttps://www.esmo.org/The latest news from ESMOen-GBnoreply@esmo.org242, 30 Aug 2025 09:08:34 +00:00242, 30 Aug 2025 09:08:34 +00:00 FDA Grants Accelerated Approval to Zongertinib for Non-squamous NSCLC with HER2 Tyrosine Kinase Domain Activating Mutations https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the Beamion LUNG-1 study</p>noreply@esmo.orgbb0dc137-253d-4b77-929b-1beb77fa87e2Fri, 29 Aug 2025 08:08:00 +00:00 Early-Stage and Locally Advanced NSCLC: ESMO Clinical Practice Guideline https://www.esmo.orgnull<p>This updated ESMO CPG provides diagnosis, staging, risk assessment, treatment and follow-up recommendations. It introduces new systemic treatments and innovative strategies, offering physicians practicing thoracic oncology advanced therapeutic options to improve outcomes and personalise care.</p>noreply@esmo.org8d7a31cc-4316-426c-9a9b-fe53dece6133Thu, 28 Aug 2025 08:08:00 +00:00 Superior EFS and OS in Patients with Nonmetastatic Osteosarcoma and Unfavourable Prognosis when Adjuvant Mifamurtide is Combined with High-Dose Ifosfamide https://www.esmo.orgnull<p>Findings from the ISG/OS-2 and GEIS-33 studies</p>noreply@esmo.org71f4b205-e613-44f8-86f1-e6b1afc68c9eThu, 28 Aug 2025 08:08:00 +00:00 Molecular Analysis for Precision Oncology Congress 2025, Paris, France, 15-16 September https://www.esmo.orgnull<p>The Molecular Analysis for Precision Oncology Congress 2025 (MAP) will bring together leading experts to explore the latest advances in cancer research, with a focus on deepening the understanding of disease mechanism and enhancing strategies for prevention and interception</p>noreply@esmo.org8b521c78-d705-426c-af80-d640aafdba56Wed, 27 Aug 2025 07:08:00 +00:00 Combining Enzalutamide with Radium-223 Significantly Improves rPFS as First-Line Therapy for Patients with mCRPC https://www.esmo.orgnull<p>Findings from the PEACE-3 study</p>noreply@esmo.orgf7879b8d-5c1c-4259-8f0d-efe16d428097Wed, 27 Aug 2025 07:08:00 +00:00 AI and remote monitoring are shaping a new patient journey in oncology https://www.esmo.orgnull<p>Real world experience suggests that the integration of digital tools into cancer care may close current gaps in patient outcomes reporting</p>noreply@esmo.org34da15a5-c125-47bd-b755-aa2474d72593Tue, 26 Aug 2025 22:08:00 +00:00 In Memory of Håkan Mellstedt: Former ESMO President https://www.esmo.orgnull<p>It is with deep sadness that ESMO has learnt of the passing of Professor Håkan Mellstedt, who died recently at the age of 82</p>noreply@esmo.org7dc6e2e0-2732-4ef0-852d-5cd9c71daf1bTue, 26 Aug 2025 12:08:00 +00:00 EMA Recommends Granting a Conditional Marketing Authorisation for Obecabtagene Autoleucel https://www.esmo.orgnull<p>It is intended for the treatment of adults from 26 years of age with relapsed or refractory B cell precursor ALL</p>noreply@esmo.orgb883a1ba-0478-438c-b5ad-b855cbfc0d09Tue, 26 Aug 2025 07:08:00 +00:00 Additional 5 Years of AI Treatment Reduces Distant Recurrence Rates Among Postmenopausal Women Already Treated with at Least 5 Years of Endocrine Therapy https://www.esmo.orgnull<p>Findings from a meta-analysis performed by the Early Breast Cancer Trialists' Collaborative Group</p>noreply@esmo.orgaae366ec-0676-4745-8c5a-f3417ecafa3eMon, 25 Aug 2025 07:08:00 +00:00 FDA Grants Accelerated Approval to Dordaviprone for Diffuse Midline Glioma https://www.esmo.orgnull<p>Evidence for efficacy is based on results from the ONC006, ONC013, ONC014, ONC016 and ONC018 studies</p>noreply@esmo.orga619a127-a1d6-4f54-96e8-4bdf3e567f21Fri, 22 Aug 2025 07:08:00 +00:00 Clinical Benefit and Genomic Features Associations Observed with Pembrolizumab Plus Axitinib in Patients with Advanced Clear Cell RCC https://www.esmo.orgnull<p>Findings from the KEYNOTE-426 study</p>noreply@esmo.org36cbe128-7def-4a17-9bd8-c253a9dfb8aaThu, 21 Aug 2025 07:08:00 +00:00 Adagrasib Improves PFS Over Docetaxel in Patients with Previously Treated KRASG12C-mutated NSCLC https://www.esmo.orgnull<p>Findings from the KRYSTAL-12 study</p>noreply@esmo.org8c65622a-b33b-4f13-8f22-12eb2c009b82Wed, 20 Aug 2025 07:08:00 +00:00 No Survival Benefit from Adding Adjuvant Chemotherapy to Endocrine Therapy in Older Women with a Genomic Grade Index High-Risk ER-positive, HER2-negative Breast Cancer https://www.esmo.orgnull<p>Findings from the ASTER 70s study</p>noreply@esmo.org2d825557-d2eb-4f7f-acb9-251237054d65Tue, 19 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Belantamab Mafodotin https://www.esmo.orgnull<p>It is intended for the treatment of patients with relapsed or refractory multiple myeloma</p>noreply@esmo.org965f5a4a-9a84-430c-bc6f-e40ca62558f5Mon, 18 Aug 2025 07:08:00 +00:00 ESMO Joins the European Health Alliance on Alcohol (EHAA) Seeking to Reduce Preventable Cancer Cases Linked to Alcohol Use https://www.esmo.orgnull<p>With alcohol consumption increasing the risk of developing at least 7 types of cancer, ESMO considers it crucial that robust policy action - at all political levels - is taken to effectively address the impact of alcohol-related harm on human health, thus enhancing cancer prevention</p>noreply@esmo.org796a42df-36fd-4a93-9ee2-41fa00b14ba2Thu, 14 Aug 2025 09:08:00 +00:00 CLDN18.2-Specific CAR T-Cell Therapy Prolongs PFS in Patients with Previously Treated Advanced Gastric or Gastro-oesophageal Junction Cancer https://www.esmo.orgnull<p>Findings from the CT041-ST-01 study</p>noreply@esmo.orgbebed821-c39b-48c2-bce8-7c5c96e4a8dbThu, 14 Aug 2025 07:08:00 +00:00 FDA Approves Tafasitamab-cxix for Relapsed or Refractory Follicular Lymphoma https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the inMIND study</p>noreply@esmo.org5e4115df-3e7b-4e40-bf32-d67663bd25ceThu, 14 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Vorasidenib https://www.esmo.orgnull<p>It is intended for the treatment of adults and adolescents with low grade astrocytoma or oligodendroglioma with an <em>IDH1</em> R132 or <em>IDH2</em> R172 mutation</p>noreply@esmo.org33595183-53c1-46d7-8d11-8efbe77ad103Wed, 13 Aug 2025 07:08:00 +00:00 Postoperative Radioiodine Can Be Avoided in Patients with Low-Risk Differentiated Thyroid Cancer https://www.esmo.orgnull<p>Findings from the IoN&nbsp;study</p>noreply@esmo.orgf44a7b22-946b-4057-90c0-b17c5d006568Tue, 12 Aug 2025 07:08:00 +00:00 ESMO Recommendations on Cancer Care Reflected in UN ECOSOC Ministerial Declaration on Sustainable Development https://www.esmo.orgnull<p>At the conclusion of the 2025 High-Level Political Forum (HLPF) on Sustainable Development, UN Member States adopted a Ministerial Declaration reaffirming commitment to universal health coverage (UHC), resilient health systems, and tackling non-communicable diseases (NCDs) like cancer</p>noreply@esmo.org1bac8e44-2826-4e2e-941a-7cda78fe8ffaMon, 11 Aug 2025 07:08:00 +00:00 ESMO Newshttps://www.esmo.org/The latest news from ESMOen-GBnoreply@esmo.org242, 30 Aug 2025 09:08:72 +00:00242, 30 Aug 2025 09:08:72 +00:00 FDA Grants Accelerated Approval to Zongertinib for Non-squamous NSCLC with HER2 Tyrosine Kinase Domain Activating Mutations https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the Beamion LUNG-1 study</p>noreply@esmo.orgbb0dc137-253d-4b77-929b-1beb77fa87e2Fri, 29 Aug 2025 08:08:00 +00:00 Early-Stage and Locally Advanced NSCLC: ESMO Clinical Practice Guideline https://www.esmo.orgnull<p>This updated ESMO CPG provides diagnosis, staging, risk assessment, treatment and follow-up recommendations. It introduces new systemic treatments and innovative strategies, offering physicians practicing thoracic oncology advanced therapeutic options to improve outcomes and personalise care.</p>noreply@esmo.org8d7a31cc-4316-426c-9a9b-fe53dece6133Thu, 28 Aug 2025 08:08:00 +00:00 Superior EFS and OS in Patients with Nonmetastatic Osteosarcoma and Unfavourable Prognosis when Adjuvant Mifamurtide is Combined with High-Dose Ifosfamide https://www.esmo.orgnull<p>Findings from the ISG/OS-2 and GEIS-33 studies</p>noreply@esmo.org71f4b205-e613-44f8-86f1-e6b1afc68c9eThu, 28 Aug 2025 08:08:00 +00:00 Molecular Analysis for Precision Oncology Congress 2025, Paris, France, 15-16 September https://www.esmo.orgnull<p>The Molecular Analysis for Precision Oncology Congress 2025 (MAP) will bring together leading experts to explore the latest advances in cancer research, with a focus on deepening the understanding of disease mechanism and enhancing strategies for prevention and interception</p>noreply@esmo.org8b521c78-d705-426c-af80-d640aafdba56Wed, 27 Aug 2025 07:08:00 +00:00 Combining Enzalutamide with Radium-223 Significantly Improves rPFS as First-Line Therapy for Patients with mCRPC https://www.esmo.orgnull<p>Findings from the PEACE-3 study</p>noreply@esmo.orgf7879b8d-5c1c-4259-8f0d-efe16d428097Wed, 27 Aug 2025 07:08:00 +00:00 AI and remote monitoring are shaping a new patient journey in oncology https://www.esmo.orgnull<p>Real world experience suggests that the integration of digital tools into cancer care may close current gaps in patient outcomes reporting</p>noreply@esmo.org34da15a5-c125-47bd-b755-aa2474d72593Tue, 26 Aug 2025 22:08:00 +00:00 In Memory of Håkan Mellstedt: Former ESMO President https://www.esmo.orgnull<p>It is with deep sadness that ESMO has learnt of the passing of Professor Håkan Mellstedt, who died recently at the age of 82</p>noreply@esmo.org7dc6e2e0-2732-4ef0-852d-5cd9c71daf1bTue, 26 Aug 2025 12:08:00 +00:00 EMA Recommends Granting a Conditional Marketing Authorisation for Obecabtagene Autoleucel https://www.esmo.orgnull<p>It is intended for the treatment of adults from 26 years of age with relapsed or refractory B cell precursor ALL</p>noreply@esmo.orgb883a1ba-0478-438c-b5ad-b855cbfc0d09Tue, 26 Aug 2025 07:08:00 +00:00 Additional 5 Years of AI Treatment Reduces Distant Recurrence Rates Among Postmenopausal Women Already Treated with at Least 5 Years of Endocrine Therapy https://www.esmo.orgnull<p>Findings from a meta-analysis performed by the Early Breast Cancer Trialists' Collaborative Group</p>noreply@esmo.orgaae366ec-0676-4745-8c5a-f3417ecafa3eMon, 25 Aug 2025 07:08:00 +00:00 FDA Grants Accelerated Approval to Dordaviprone for Diffuse Midline Glioma https://www.esmo.orgnull<p>Evidence for efficacy is based on results from the ONC006, ONC013, ONC014, ONC016 and ONC018 studies</p>noreply@esmo.orga619a127-a1d6-4f54-96e8-4bdf3e567f21Fri, 22 Aug 2025 07:08:00 +00:00 Clinical Benefit and Genomic Features Associations Observed with Pembrolizumab Plus Axitinib in Patients with Advanced Clear Cell RCC https://www.esmo.orgnull<p>Findings from the KEYNOTE-426 study</p>noreply@esmo.org36cbe128-7def-4a17-9bd8-c253a9dfb8aaThu, 21 Aug 2025 07:08:00 +00:00 Adagrasib Improves PFS Over Docetaxel in Patients with Previously Treated KRASG12C-mutated NSCLC https://www.esmo.orgnull<p>Findings from the KRYSTAL-12 study</p>noreply@esmo.org8c65622a-b33b-4f13-8f22-12eb2c009b82Wed, 20 Aug 2025 07:08:00 +00:00 No Survival Benefit from Adding Adjuvant Chemotherapy to Endocrine Therapy in Older Women with a Genomic Grade Index High-Risk ER-positive, HER2-negative Breast Cancer https://www.esmo.orgnull<p>Findings from the ASTER 70s study</p>noreply@esmo.org2d825557-d2eb-4f7f-acb9-251237054d65Tue, 19 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Belantamab Mafodotin https://www.esmo.orgnull<p>It is intended for the treatment of patients with relapsed or refractory multiple myeloma</p>noreply@esmo.org965f5a4a-9a84-430c-bc6f-e40ca62558f5Mon, 18 Aug 2025 07:08:00 +00:00 ESMO Joins the European Health Alliance on Alcohol (EHAA) Seeking to Reduce Preventable Cancer Cases Linked to Alcohol Use https://www.esmo.orgnull<p>With alcohol consumption increasing the risk of developing at least 7 types of cancer, ESMO considers it crucial that robust policy action - at all political levels - is taken to effectively address the impact of alcohol-related harm on human health, thus enhancing cancer prevention</p>noreply@esmo.org796a42df-36fd-4a93-9ee2-41fa00b14ba2Thu, 14 Aug 2025 09:08:00 +00:00 CLDN18.2-Specific CAR T-Cell Therapy Prolongs PFS in Patients with Previously Treated Advanced Gastric or Gastro-oesophageal Junction Cancer https://www.esmo.orgnull<p>Findings from the CT041-ST-01 study</p>noreply@esmo.orgbebed821-c39b-48c2-bce8-7c5c96e4a8dbThu, 14 Aug 2025 07:08:00 +00:00 FDA Approves Tafasitamab-cxix for Relapsed or Refractory Follicular Lymphoma https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the inMIND study</p>noreply@esmo.org5e4115df-3e7b-4e40-bf32-d67663bd25ceThu, 14 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Vorasidenib https://www.esmo.orgnull<p>It is intended for the treatment of adults and adolescents with low grade astrocytoma or oligodendroglioma with an <em>IDH1</em> R132 or <em>IDH2</em> R172 mutation</p>noreply@esmo.org33595183-53c1-46d7-8d11-8efbe77ad103Wed, 13 Aug 2025 07:08:00 +00:00 Postoperative Radioiodine Can Be Avoided in Patients with Low-Risk Differentiated Thyroid Cancer https://www.esmo.orgnull<p>Findings from the IoN&nbsp;study</p>noreply@esmo.orgf44a7b22-946b-4057-90c0-b17c5d006568Tue, 12 Aug 2025 07:08:00 +00:00 ESMO Recommendations on Cancer Care Reflected in UN ECOSOC Ministerial Declaration on Sustainable Development https://www.esmo.orgnull<p>At the conclusion of the 2025 High-Level Political Forum (HLPF) on Sustainable Development, UN Member States adopted a Ministerial Declaration reaffirming commitment to universal health coverage (UHC), resilient health systems, and tackling non-communicable diseases (NCDs) like cancer</p>noreply@esmo.org1bac8e44-2826-4e2e-941a-7cda78fe8ffaMon, 11 Aug 2025 07:08:00 +00:00 ESMO Newshttps://www.esmo.org/The latest news from ESMOen-GBnoreply@esmo.org242, 30 Aug 2025 09:08:26 +00:00242, 30 Aug 2025 09:08:26 +00:00 FDA Grants Accelerated Approval to Zongertinib for Non-squamous NSCLC with HER2 Tyrosine Kinase Domain Activating Mutations https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the Beamion LUNG-1 study</p>noreply@esmo.orgbb0dc137-253d-4b77-929b-1beb77fa87e2Fri, 29 Aug 2025 08:08:00 +00:00 Early-Stage and Locally Advanced NSCLC: ESMO Clinical Practice Guideline https://www.esmo.orgnull<p>This updated ESMO CPG provides diagnosis, staging, risk assessment, treatment and follow-up recommendations. It introduces new systemic treatments and innovative strategies, offering physicians practicing thoracic oncology advanced therapeutic options to improve outcomes and personalise care.</p>noreply@esmo.org8d7a31cc-4316-426c-9a9b-fe53dece6133Thu, 28 Aug 2025 08:08:00 +00:00 Superior EFS and OS in Patients with Nonmetastatic Osteosarcoma and Unfavourable Prognosis when Adjuvant Mifamurtide is Combined with High-Dose Ifosfamide https://www.esmo.orgnull<p>Findings from the ISG/OS-2 and GEIS-33 studies</p>noreply@esmo.org71f4b205-e613-44f8-86f1-e6b1afc68c9eThu, 28 Aug 2025 08:08:00 +00:00 Molecular Analysis for Precision Oncology Congress 2025, Paris, France, 15-16 September https://www.esmo.orgnull<p>The Molecular Analysis for Precision Oncology Congress 2025 (MAP) will bring together leading experts to explore the latest advances in cancer research, with a focus on deepening the understanding of disease mechanism and enhancing strategies for prevention and interception</p>noreply@esmo.org8b521c78-d705-426c-af80-d640aafdba56Wed, 27 Aug 2025 07:08:00 +00:00 Combining Enzalutamide with Radium-223 Significantly Improves rPFS as First-Line Therapy for Patients with mCRPC https://www.esmo.orgnull<p>Findings from the PEACE-3 study</p>noreply@esmo.orgf7879b8d-5c1c-4259-8f0d-efe16d428097Wed, 27 Aug 2025 07:08:00 +00:00 AI and remote monitoring are shaping a new patient journey in oncology https://www.esmo.orgnull<p>Real world experience suggests that the integration of digital tools into cancer care may close current gaps in patient outcomes reporting</p>noreply@esmo.org34da15a5-c125-47bd-b755-aa2474d72593Tue, 26 Aug 2025 22:08:00 +00:00 In Memory of Håkan Mellstedt: Former ESMO President https://www.esmo.orgnull<p>It is with deep sadness that ESMO has learnt of the passing of Professor Håkan Mellstedt, who died recently at the age of 82</p>noreply@esmo.org7dc6e2e0-2732-4ef0-852d-5cd9c71daf1bTue, 26 Aug 2025 12:08:00 +00:00 EMA Recommends Granting a Conditional Marketing Authorisation for Obecabtagene Autoleucel https://www.esmo.orgnull<p>It is intended for the treatment of adults from 26 years of age with relapsed or refractory B cell precursor ALL</p>noreply@esmo.orgb883a1ba-0478-438c-b5ad-b855cbfc0d09Tue, 26 Aug 2025 07:08:00 +00:00 Additional 5 Years of AI Treatment Reduces Distant Recurrence Rates Among Postmenopausal Women Already Treated with at Least 5 Years of Endocrine Therapy https://www.esmo.orgnull<p>Findings from a meta-analysis performed by the Early Breast Cancer Trialists' Collaborative Group</p>noreply@esmo.orgaae366ec-0676-4745-8c5a-f3417ecafa3eMon, 25 Aug 2025 07:08:00 +00:00 FDA Grants Accelerated Approval to Dordaviprone for Diffuse Midline Glioma https://www.esmo.orgnull<p>Evidence for efficacy is based on results from the ONC006, ONC013, ONC014, ONC016 and ONC018 studies</p>noreply@esmo.orga619a127-a1d6-4f54-96e8-4bdf3e567f21Fri, 22 Aug 2025 07:08:00 +00:00 Clinical Benefit and Genomic Features Associations Observed with Pembrolizumab Plus Axitinib in Patients with Advanced Clear Cell RCC https://www.esmo.orgnull<p>Findings from the KEYNOTE-426 study</p>noreply@esmo.org36cbe128-7def-4a17-9bd8-c253a9dfb8aaThu, 21 Aug 2025 07:08:00 +00:00 Adagrasib Improves PFS Over Docetaxel in Patients with Previously Treated KRASG12C-mutated NSCLC https://www.esmo.orgnull<p>Findings from the KRYSTAL-12 study</p>noreply@esmo.org8c65622a-b33b-4f13-8f22-12eb2c009b82Wed, 20 Aug 2025 07:08:00 +00:00 No Survival Benefit from Adding Adjuvant Chemotherapy to Endocrine Therapy in Older Women with a Genomic Grade Index High-Risk ER-positive, HER2-negative Breast Cancer https://www.esmo.orgnull<p>Findings from the ASTER 70s study</p>noreply@esmo.org2d825557-d2eb-4f7f-acb9-251237054d65Tue, 19 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Belantamab Mafodotin https://www.esmo.orgnull<p>It is intended for the treatment of patients with relapsed or refractory multiple myeloma</p>noreply@esmo.org965f5a4a-9a84-430c-bc6f-e40ca62558f5Mon, 18 Aug 2025 07:08:00 +00:00 ESMO Joins the European Health Alliance on Alcohol (EHAA) Seeking to Reduce Preventable Cancer Cases Linked to Alcohol Use https://www.esmo.orgnull<p>With alcohol consumption increasing the risk of developing at least 7 types of cancer, ESMO considers it crucial that robust policy action - at all political levels - is taken to effectively address the impact of alcohol-related harm on human health, thus enhancing cancer prevention</p>noreply@esmo.org796a42df-36fd-4a93-9ee2-41fa00b14ba2Thu, 14 Aug 2025 09:08:00 +00:00 CLDN18.2-Specific CAR T-Cell Therapy Prolongs PFS in Patients with Previously Treated Advanced Gastric or Gastro-oesophageal Junction Cancer https://www.esmo.orgnull<p>Findings from the CT041-ST-01 study</p>noreply@esmo.orgbebed821-c39b-48c2-bce8-7c5c96e4a8dbThu, 14 Aug 2025 07:08:00 +00:00 FDA Approves Tafasitamab-cxix for Relapsed or Refractory Follicular Lymphoma https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the inMIND study</p>noreply@esmo.org5e4115df-3e7b-4e40-bf32-d67663bd25ceThu, 14 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Vorasidenib https://www.esmo.orgnull<p>It is intended for the treatment of adults and adolescents with low grade astrocytoma or oligodendroglioma with an <em>IDH1</em> R132 or <em>IDH2</em> R172 mutation</p>noreply@esmo.org33595183-53c1-46d7-8d11-8efbe77ad103Wed, 13 Aug 2025 07:08:00 +00:00 Postoperative Radioiodine Can Be Avoided in Patients with Low-Risk Differentiated Thyroid Cancer https://www.esmo.orgnull<p>Findings from the IoN&nbsp;study</p>noreply@esmo.orgf44a7b22-946b-4057-90c0-b17c5d006568Tue, 12 Aug 2025 07:08:00 +00:00 ESMO Recommendations on Cancer Care Reflected in UN ECOSOC Ministerial Declaration on Sustainable Development https://www.esmo.orgnull<p>At the conclusion of the 2025 High-Level Political Forum (HLPF) on Sustainable Development, UN Member States adopted a Ministerial Declaration reaffirming commitment to universal health coverage (UHC), resilient health systems, and tackling non-communicable diseases (NCDs) like cancer</p>noreply@esmo.org1bac8e44-2826-4e2e-941a-7cda78fe8ffaMon, 11 Aug 2025 07:08:00 +00:00 ESMO Newshttps://www.esmo.org/The latest news from ESMOen-GBnoreply@esmo.org242, 30 Aug 2025 09:08:40 +00:00242, 30 Aug 2025 09:08:40 +00:00 FDA Grants Accelerated Approval to Zongertinib for Non-squamous NSCLC with HER2 Tyrosine Kinase Domain Activating Mutations https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the Beamion LUNG-1 study</p>noreply@esmo.orgbb0dc137-253d-4b77-929b-1beb77fa87e2Fri, 29 Aug 2025 08:08:00 +00:00 Early-Stage and Locally Advanced NSCLC: ESMO Clinical Practice Guideline https://www.esmo.orgnull<p>This updated ESMO CPG provides diagnosis, staging, risk assessment, treatment and follow-up recommendations. It introduces new systemic treatments and innovative strategies, offering physicians practicing thoracic oncology advanced therapeutic options to improve outcomes and personalise care.</p>noreply@esmo.org8d7a31cc-4316-426c-9a9b-fe53dece6133Thu, 28 Aug 2025 08:08:00 +00:00 Superior EFS and OS in Patients with Nonmetastatic Osteosarcoma and Unfavourable Prognosis when Adjuvant Mifamurtide is Combined with High-Dose Ifosfamide https://www.esmo.orgnull<p>Findings from the ISG/OS-2 and GEIS-33 studies</p>noreply@esmo.org71f4b205-e613-44f8-86f1-e6b1afc68c9eThu, 28 Aug 2025 08:08:00 +00:00 Molecular Analysis for Precision Oncology Congress 2025, Paris, France, 15-16 September https://www.esmo.orgnull<p>The Molecular Analysis for Precision Oncology Congress 2025 (MAP) will bring together leading experts to explore the latest advances in cancer research, with a focus on deepening the understanding of disease mechanism and enhancing strategies for prevention and interception</p>noreply@esmo.org8b521c78-d705-426c-af80-d640aafdba56Wed, 27 Aug 2025 07:08:00 +00:00 Combining Enzalutamide with Radium-223 Significantly Improves rPFS as First-Line Therapy for Patients with mCRPC https://www.esmo.orgnull<p>Findings from the PEACE-3 study</p>noreply@esmo.orgf7879b8d-5c1c-4259-8f0d-efe16d428097Wed, 27 Aug 2025 07:08:00 +00:00 AI and remote monitoring are shaping a new patient journey in oncology https://www.esmo.orgnull<p>Real world experience suggests that the integration of digital tools into cancer care may close current gaps in patient outcomes reporting</p>noreply@esmo.org34da15a5-c125-47bd-b755-aa2474d72593Tue, 26 Aug 2025 22:08:00 +00:00 In Memory of Håkan Mellstedt: Former ESMO President https://www.esmo.orgnull<p>It is with deep sadness that ESMO has learnt of the passing of Professor Håkan Mellstedt, who died recently at the age of 82</p>noreply@esmo.org7dc6e2e0-2732-4ef0-852d-5cd9c71daf1bTue, 26 Aug 2025 12:08:00 +00:00 EMA Recommends Granting a Conditional Marketing Authorisation for Obecabtagene Autoleucel https://www.esmo.orgnull<p>It is intended for the treatment of adults from 26 years of age with relapsed or refractory B cell precursor ALL</p>noreply@esmo.orgb883a1ba-0478-438c-b5ad-b855cbfc0d09Tue, 26 Aug 2025 07:08:00 +00:00 Additional 5 Years of AI Treatment Reduces Distant Recurrence Rates Among Postmenopausal Women Already Treated with at Least 5 Years of Endocrine Therapy https://www.esmo.orgnull<p>Findings from a meta-analysis performed by the Early Breast Cancer Trialists' Collaborative Group</p>noreply@esmo.orgaae366ec-0676-4745-8c5a-f3417ecafa3eMon, 25 Aug 2025 07:08:00 +00:00 FDA Grants Accelerated Approval to Dordaviprone for Diffuse Midline Glioma https://www.esmo.orgnull<p>Evidence for efficacy is based on results from the ONC006, ONC013, ONC014, ONC016 and ONC018 studies</p>noreply@esmo.orga619a127-a1d6-4f54-96e8-4bdf3e567f21Fri, 22 Aug 2025 07:08:00 +00:00 Clinical Benefit and Genomic Features Associations Observed with Pembrolizumab Plus Axitinib in Patients with Advanced Clear Cell RCC https://www.esmo.orgnull<p>Findings from the KEYNOTE-426 study</p>noreply@esmo.org36cbe128-7def-4a17-9bd8-c253a9dfb8aaThu, 21 Aug 2025 07:08:00 +00:00 Adagrasib Improves PFS Over Docetaxel in Patients with Previously Treated KRASG12C-mutated NSCLC https://www.esmo.orgnull<p>Findings from the KRYSTAL-12 study</p>noreply@esmo.org8c65622a-b33b-4f13-8f22-12eb2c009b82Wed, 20 Aug 2025 07:08:00 +00:00 No Survival Benefit from Adding Adjuvant Chemotherapy to Endocrine Therapy in Older Women with a Genomic Grade Index High-Risk ER-positive, HER2-negative Breast Cancer https://www.esmo.orgnull<p>Findings from the ASTER 70s study</p>noreply@esmo.org2d825557-d2eb-4f7f-acb9-251237054d65Tue, 19 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Belantamab Mafodotin https://www.esmo.orgnull<p>It is intended for the treatment of patients with relapsed or refractory multiple myeloma</p>noreply@esmo.org965f5a4a-9a84-430c-bc6f-e40ca62558f5Mon, 18 Aug 2025 07:08:00 +00:00 ESMO Joins the European Health Alliance on Alcohol (EHAA) Seeking to Reduce Preventable Cancer Cases Linked to Alcohol Use https://www.esmo.orgnull<p>With alcohol consumption increasing the risk of developing at least 7 types of cancer, ESMO considers it crucial that robust policy action - at all political levels - is taken to effectively address the impact of alcohol-related harm on human health, thus enhancing cancer prevention</p>noreply@esmo.org796a42df-36fd-4a93-9ee2-41fa00b14ba2Thu, 14 Aug 2025 09:08:00 +00:00 CLDN18.2-Specific CAR T-Cell Therapy Prolongs PFS in Patients with Previously Treated Advanced Gastric or Gastro-oesophageal Junction Cancer https://www.esmo.orgnull<p>Findings from the CT041-ST-01 study</p>noreply@esmo.orgbebed821-c39b-48c2-bce8-7c5c96e4a8dbThu, 14 Aug 2025 07:08:00 +00:00 FDA Approves Tafasitamab-cxix for Relapsed or Refractory Follicular Lymphoma https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the inMIND study</p>noreply@esmo.org5e4115df-3e7b-4e40-bf32-d67663bd25ceThu, 14 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Vorasidenib https://www.esmo.orgnull<p>It is intended for the treatment of adults and adolescents with low grade astrocytoma or oligodendroglioma with an <em>IDH1</em> R132 or <em>IDH2</em> R172 mutation</p>noreply@esmo.org33595183-53c1-46d7-8d11-8efbe77ad103Wed, 13 Aug 2025 07:08:00 +00:00 Postoperative Radioiodine Can Be Avoided in Patients with Low-Risk Differentiated Thyroid Cancer https://www.esmo.orgnull<p>Findings from the IoN&nbsp;study</p>noreply@esmo.orgf44a7b22-946b-4057-90c0-b17c5d006568Tue, 12 Aug 2025 07:08:00 +00:00 ESMO Recommendations on Cancer Care Reflected in UN ECOSOC Ministerial Declaration on Sustainable Development https://www.esmo.orgnull<p>At the conclusion of the 2025 High-Level Political Forum (HLPF) on Sustainable Development, UN Member States adopted a Ministerial Declaration reaffirming commitment to universal health coverage (UHC), resilient health systems, and tackling non-communicable diseases (NCDs) like cancer</p>noreply@esmo.org1bac8e44-2826-4e2e-941a-7cda78fe8ffaMon, 11 Aug 2025 07:08:00 +00:00 ESMO Newshttps://www.esmo.org/The latest news from ESMOen-GBnoreply@esmo.org242, 30 Aug 2025 09:08:87 +00:00242, 30 Aug 2025 09:08:87 +00:00 FDA Grants Accelerated Approval to Zongertinib for Non-squamous NSCLC with HER2 Tyrosine Kinase Domain Activating Mutations https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the Beamion LUNG-1 study</p>noreply@esmo.orgbb0dc137-253d-4b77-929b-1beb77fa87e2Fri, 29 Aug 2025 08:08:00 +00:00 Early-Stage and Locally Advanced NSCLC: ESMO Clinical Practice Guideline https://www.esmo.orgnull<p>This updated ESMO CPG provides diagnosis, staging, risk assessment, treatment and follow-up recommendations. It introduces new systemic treatments and innovative strategies, offering physicians practicing thoracic oncology advanced therapeutic options to improve outcomes and personalise care.</p>noreply@esmo.org8d7a31cc-4316-426c-9a9b-fe53dece6133Thu, 28 Aug 2025 08:08:00 +00:00 Superior EFS and OS in Patients with Nonmetastatic Osteosarcoma and Unfavourable Prognosis when Adjuvant Mifamurtide is Combined with High-Dose Ifosfamide https://www.esmo.orgnull<p>Findings from the ISG/OS-2 and GEIS-33 studies</p>noreply@esmo.org71f4b205-e613-44f8-86f1-e6b1afc68c9eThu, 28 Aug 2025 08:08:00 +00:00 Molecular Analysis for Precision Oncology Congress 2025, Paris, France, 15-16 September https://www.esmo.orgnull<p>The Molecular Analysis for Precision Oncology Congress 2025 (MAP) will bring together leading experts to explore the latest advances in cancer research, with a focus on deepening the understanding of disease mechanism and enhancing strategies for prevention and interception</p>noreply@esmo.org8b521c78-d705-426c-af80-d640aafdba56Wed, 27 Aug 2025 07:08:00 +00:00 Combining Enzalutamide with Radium-223 Significantly Improves rPFS as First-Line Therapy for Patients with mCRPC https://www.esmo.orgnull<p>Findings from the PEACE-3 study</p>noreply@esmo.orgf7879b8d-5c1c-4259-8f0d-efe16d428097Wed, 27 Aug 2025 07:08:00 +00:00 AI and remote monitoring are shaping a new patient journey in oncology https://www.esmo.orgnull<p>Real world experience suggests that the integration of digital tools into cancer care may close current gaps in patient outcomes reporting</p>noreply@esmo.org34da15a5-c125-47bd-b755-aa2474d72593Tue, 26 Aug 2025 22:08:00 +00:00 In Memory of Håkan Mellstedt: Former ESMO President https://www.esmo.orgnull<p>It is with deep sadness that ESMO has learnt of the passing of Professor Håkan Mellstedt, who died recently at the age of 82</p>noreply@esmo.org7dc6e2e0-2732-4ef0-852d-5cd9c71daf1bTue, 26 Aug 2025 12:08:00 +00:00 EMA Recommends Granting a Conditional Marketing Authorisation for Obecabtagene Autoleucel https://www.esmo.orgnull<p>It is intended for the treatment of adults from 26 years of age with relapsed or refractory B cell precursor ALL</p>noreply@esmo.orgb883a1ba-0478-438c-b5ad-b855cbfc0d09Tue, 26 Aug 2025 07:08:00 +00:00 Additional 5 Years of AI Treatment Reduces Distant Recurrence Rates Among Postmenopausal Women Already Treated with at Least 5 Years of Endocrine Therapy https://www.esmo.orgnull<p>Findings from a meta-analysis performed by the Early Breast Cancer Trialists' Collaborative Group</p>noreply@esmo.orgaae366ec-0676-4745-8c5a-f3417ecafa3eMon, 25 Aug 2025 07:08:00 +00:00 FDA Grants Accelerated Approval to Dordaviprone for Diffuse Midline Glioma https://www.esmo.orgnull<p>Evidence for efficacy is based on results from the ONC006, ONC013, ONC014, ONC016 and ONC018 studies</p>noreply@esmo.orga619a127-a1d6-4f54-96e8-4bdf3e567f21Fri, 22 Aug 2025 07:08:00 +00:00 Clinical Benefit and Genomic Features Associations Observed with Pembrolizumab Plus Axitinib in Patients with Advanced Clear Cell RCC https://www.esmo.orgnull<p>Findings from the KEYNOTE-426 study</p>noreply@esmo.org36cbe128-7def-4a17-9bd8-c253a9dfb8aaThu, 21 Aug 2025 07:08:00 +00:00 Adagrasib Improves PFS Over Docetaxel in Patients with Previously Treated KRASG12C-mutated NSCLC https://www.esmo.orgnull<p>Findings from the KRYSTAL-12 study</p>noreply@esmo.org8c65622a-b33b-4f13-8f22-12eb2c009b82Wed, 20 Aug 2025 07:08:00 +00:00 No Survival Benefit from Adding Adjuvant Chemotherapy to Endocrine Therapy in Older Women with a Genomic Grade Index High-Risk ER-positive, HER2-negative Breast Cancer https://www.esmo.orgnull<p>Findings from the ASTER 70s study</p>noreply@esmo.org2d825557-d2eb-4f7f-acb9-251237054d65Tue, 19 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Belantamab Mafodotin https://www.esmo.orgnull<p>It is intended for the treatment of patients with relapsed or refractory multiple myeloma</p>noreply@esmo.org965f5a4a-9a84-430c-bc6f-e40ca62558f5Mon, 18 Aug 2025 07:08:00 +00:00 ESMO Joins the European Health Alliance on Alcohol (EHAA) Seeking to Reduce Preventable Cancer Cases Linked to Alcohol Use https://www.esmo.orgnull<p>With alcohol consumption increasing the risk of developing at least 7 types of cancer, ESMO considers it crucial that robust policy action - at all political levels - is taken to effectively address the impact of alcohol-related harm on human health, thus enhancing cancer prevention</p>noreply@esmo.org796a42df-36fd-4a93-9ee2-41fa00b14ba2Thu, 14 Aug 2025 09:08:00 +00:00 CLDN18.2-Specific CAR T-Cell Therapy Prolongs PFS in Patients with Previously Treated Advanced Gastric or Gastro-oesophageal Junction Cancer https://www.esmo.orgnull<p>Findings from the CT041-ST-01 study</p>noreply@esmo.orgbebed821-c39b-48c2-bce8-7c5c96e4a8dbThu, 14 Aug 2025 07:08:00 +00:00 FDA Approves Tafasitamab-cxix for Relapsed or Refractory Follicular Lymphoma https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the inMIND study</p>noreply@esmo.org5e4115df-3e7b-4e40-bf32-d67663bd25ceThu, 14 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Vorasidenib https://www.esmo.orgnull<p>It is intended for the treatment of adults and adolescents with low grade astrocytoma or oligodendroglioma with an <em>IDH1</em> R132 or <em>IDH2</em> R172 mutation</p>noreply@esmo.org33595183-53c1-46d7-8d11-8efbe77ad103Wed, 13 Aug 2025 07:08:00 +00:00 Postoperative Radioiodine Can Be Avoided in Patients with Low-Risk Differentiated Thyroid Cancer https://www.esmo.orgnull<p>Findings from the IoN&nbsp;study</p>noreply@esmo.orgf44a7b22-946b-4057-90c0-b17c5d006568Tue, 12 Aug 2025 07:08:00 +00:00 ESMO Recommendations on Cancer Care Reflected in UN ECOSOC Ministerial Declaration on Sustainable Development https://www.esmo.orgnull<p>At the conclusion of the 2025 High-Level Political Forum (HLPF) on Sustainable Development, UN Member States adopted a Ministerial Declaration reaffirming commitment to universal health coverage (UHC), resilient health systems, and tackling non-communicable diseases (NCDs) like cancer</p>noreply@esmo.org1bac8e44-2826-4e2e-941a-7cda78fe8ffaMon, 11 Aug 2025 07:08:00 +00:00 ESMO Newshttps://www.esmo.org/The latest news from ESMOen-GBnoreply@esmo.org242, 30 Aug 2025 09:08:38 +00:00242, 30 Aug 2025 09:08:38 +00:00 FDA Grants Accelerated Approval to Zongertinib for Non-squamous NSCLC with HER2 Tyrosine Kinase Domain Activating Mutations https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the Beamion LUNG-1 study</p>noreply@esmo.orgbb0dc137-253d-4b77-929b-1beb77fa87e2Fri, 29 Aug 2025 08:08:00 +00:00 Early-Stage and Locally Advanced NSCLC: ESMO Clinical Practice Guideline https://www.esmo.orgnull<p>This updated ESMO CPG provides diagnosis, staging, risk assessment, treatment and follow-up recommendations. It introduces new systemic treatments and innovative strategies, offering physicians practicing thoracic oncology advanced therapeutic options to improve outcomes and personalise care.</p>noreply@esmo.org8d7a31cc-4316-426c-9a9b-fe53dece6133Thu, 28 Aug 2025 08:08:00 +00:00 Superior EFS and OS in Patients with Nonmetastatic Osteosarcoma and Unfavourable Prognosis when Adjuvant Mifamurtide is Combined with High-Dose Ifosfamide https://www.esmo.orgnull<p>Findings from the ISG/OS-2 and GEIS-33 studies</p>noreply@esmo.org71f4b205-e613-44f8-86f1-e6b1afc68c9eThu, 28 Aug 2025 08:08:00 +00:00 Molecular Analysis for Precision Oncology Congress 2025, Paris, France, 15-16 September https://www.esmo.orgnull<p>The Molecular Analysis for Precision Oncology Congress 2025 (MAP) will bring together leading experts to explore the latest advances in cancer research, with a focus on deepening the understanding of disease mechanism and enhancing strategies for prevention and interception</p>noreply@esmo.org8b521c78-d705-426c-af80-d640aafdba56Wed, 27 Aug 2025 07:08:00 +00:00 Combining Enzalutamide with Radium-223 Significantly Improves rPFS as First-Line Therapy for Patients with mCRPC https://www.esmo.orgnull<p>Findings from the PEACE-3 study</p>noreply@esmo.orgf7879b8d-5c1c-4259-8f0d-efe16d428097Wed, 27 Aug 2025 07:08:00 +00:00 AI and remote monitoring are shaping a new patient journey in oncology https://www.esmo.orgnull<p>Real world experience suggests that the integration of digital tools into cancer care may close current gaps in patient outcomes reporting</p>noreply@esmo.org34da15a5-c125-47bd-b755-aa2474d72593Tue, 26 Aug 2025 22:08:00 +00:00 In Memory of Håkan Mellstedt: Former ESMO President https://www.esmo.orgnull<p>It is with deep sadness that ESMO has learnt of the passing of Professor Håkan Mellstedt, who died recently at the age of 82</p>noreply@esmo.org7dc6e2e0-2732-4ef0-852d-5cd9c71daf1bTue, 26 Aug 2025 12:08:00 +00:00 EMA Recommends Granting a Conditional Marketing Authorisation for Obecabtagene Autoleucel https://www.esmo.orgnull<p>It is intended for the treatment of adults from 26 years of age with relapsed or refractory B cell precursor ALL</p>noreply@esmo.orgb883a1ba-0478-438c-b5ad-b855cbfc0d09Tue, 26 Aug 2025 07:08:00 +00:00 Additional 5 Years of AI Treatment Reduces Distant Recurrence Rates Among Postmenopausal Women Already Treated with at Least 5 Years of Endocrine Therapy https://www.esmo.orgnull<p>Findings from a meta-analysis performed by the Early Breast Cancer Trialists' Collaborative Group</p>noreply@esmo.orgaae366ec-0676-4745-8c5a-f3417ecafa3eMon, 25 Aug 2025 07:08:00 +00:00 FDA Grants Accelerated Approval to Dordaviprone for Diffuse Midline Glioma https://www.esmo.orgnull<p>Evidence for efficacy is based on results from the ONC006, ONC013, ONC014, ONC016 and ONC018 studies</p>noreply@esmo.orga619a127-a1d6-4f54-96e8-4bdf3e567f21Fri, 22 Aug 2025 07:08:00 +00:00 Clinical Benefit and Genomic Features Associations Observed with Pembrolizumab Plus Axitinib in Patients with Advanced Clear Cell RCC https://www.esmo.orgnull<p>Findings from the KEYNOTE-426 study</p>noreply@esmo.org36cbe128-7def-4a17-9bd8-c253a9dfb8aaThu, 21 Aug 2025 07:08:00 +00:00 Adagrasib Improves PFS Over Docetaxel in Patients with Previously Treated KRASG12C-mutated NSCLC https://www.esmo.orgnull<p>Findings from the KRYSTAL-12 study</p>noreply@esmo.org8c65622a-b33b-4f13-8f22-12eb2c009b82Wed, 20 Aug 2025 07:08:00 +00:00 No Survival Benefit from Adding Adjuvant Chemotherapy to Endocrine Therapy in Older Women with a Genomic Grade Index High-Risk ER-positive, HER2-negative Breast Cancer https://www.esmo.orgnull<p>Findings from the ASTER 70s study</p>noreply@esmo.org2d825557-d2eb-4f7f-acb9-251237054d65Tue, 19 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Belantamab Mafodotin https://www.esmo.orgnull<p>It is intended for the treatment of patients with relapsed or refractory multiple myeloma</p>noreply@esmo.org965f5a4a-9a84-430c-bc6f-e40ca62558f5Mon, 18 Aug 2025 07:08:00 +00:00 ESMO Joins the European Health Alliance on Alcohol (EHAA) Seeking to Reduce Preventable Cancer Cases Linked to Alcohol Use https://www.esmo.orgnull<p>With alcohol consumption increasing the risk of developing at least 7 types of cancer, ESMO considers it crucial that robust policy action - at all political levels - is taken to effectively address the impact of alcohol-related harm on human health, thus enhancing cancer prevention</p>noreply@esmo.org796a42df-36fd-4a93-9ee2-41fa00b14ba2Thu, 14 Aug 2025 09:08:00 +00:00 CLDN18.2-Specific CAR T-Cell Therapy Prolongs PFS in Patients with Previously Treated Advanced Gastric or Gastro-oesophageal Junction Cancer https://www.esmo.orgnull<p>Findings from the CT041-ST-01 study</p>noreply@esmo.orgbebed821-c39b-48c2-bce8-7c5c96e4a8dbThu, 14 Aug 2025 07:08:00 +00:00 FDA Approves Tafasitamab-cxix for Relapsed or Refractory Follicular Lymphoma https://www.esmo.orgnull<p>Evidence for efficacy is based on the results from the inMIND study</p>noreply@esmo.org5e4115df-3e7b-4e40-bf32-d67663bd25ceThu, 14 Aug 2025 07:08:00 +00:00 EMA Recommends Granting a Marketing Authorisation for Vorasidenib https://www.esmo.orgnull<p>It is intended for the treatment of adults and adolescents with low grade astrocytoma or oligodendroglioma with an <em>IDH1</em> R132 or <em>IDH2</em> R172 mutation</p>noreply@esmo.org33595183-53c1-46d7-8d11-8efbe77ad103Wed, 13 Aug 2025 07:08:00 +00:00 Postoperative Radioiodine Can Be Avoided in Patients with Low-Risk Differentiated Thyroid Cancer https://www.esmo.orgnull<p>Findings from the IoN&nbsp;study</p>noreply@esmo.orgf44a7b22-946b-4057-90c0-b17c5d006568Tue, 12 Aug 2025 07:08:00 +00:00 ESMO Recommendations on Cancer Care Reflected in UN ECOSOC Ministerial Declaration on Sustainable Development https://www.esmo.orgnull<p>At the conclusion of the 2025 High-Level Political Forum (HLPF) on Sustainable Development, UN Member States adopted a Ministerial Declaration reaffirming commitment to universal health coverage (UHC), resilient health systems, and tackling non-communicable diseases (NCDs) like cancer</p>noreply@esmo.org1bac8e44-2826-4e2e-941a-7cda78fe8ffaMon, 11 Aug 2025 07:08:00 +00:00