Oops, you're using an old version of your browser so some of the features on this page may not be displaying properly.

MINIMAL Requirements: Google Chrome 24+Mozilla Firefox 20+Internet Explorer 11Opera 15–18Apple Safari 7SeaMonkey 2.15-2.23

ESMO Conference on Sarcoma and GIST: Doctors lack awareness of rare forgotten cancers

Thousands of patients with rare forgotten cancers are paying a high price because doctors lack awareness of their conditions
12 Mar 2012

4th ESMO Conference on Sarcoma and GIST

Thousands of patients with rare “forgotten cancers” are paying a high price because doctors lack awareness of their conditions, according to a speaker at the 4th ESMO Conference on Sarcoma and GIST. Personal tragedies often unfold as men and women who have a rare type of cancer known as sarcoma are repeatedly misdiagnosed and given inappropriate therapies, patient advocate Markus Wartenberg told the conference held in Milan, Italy, from March 9-11, 2012.

Now in its fourth year, the ESMO Conference has become an important event for the international community of experts who research and treat sarcomas. Sarcomas are a group of more than 60 different tumour types that affect bone, muscle, fat, blood vessels and other tissues. Each of these distinct cancers is individually quite rare, however together they affect about 10,000 people in Europe each year.

“One patient I spoke to last week had been given seven different diagnoses before he was finally correctly diagnosed,” said Wartenberg, a representative of the German patient organisation Das Lebenshaus. “He is 42, and is the father of two small children. The correct diagnosis came far too late. If he had come sooner to a qualified centre, maybe his prognosis would be totally different.”

Each of the many different sarcomas requires particular treatment, meaning specialised multidisciplinary care is vital to ensure the best possible outcome. “The general problem in many countries is that many sarcoma patients are treated inappropriately, and there is not the real awareness about this group of diagnoses and sets of treatments,” said Wartenberg. "Specialised sarcoma centres are an important part of delivering that care. Where patients can access those specialised centres, their chances of a good outcome are improved," he added.

Beyond diagnosis and access to care, sarcoma patients also need new, more effective therapies. “The ESMO conference brings together cancer experts to share the latest findings about the biological mechanisms leading to sarcomas,” said Prof Jean-Yves Blay, conference co-chair. “Because sarcomas are rare, the initial management is often inadequate. Innovations that improve the rates of patient referral to expert centres could result in some cures being more easily achieved."

"However, because sarcomas have well-characterised molecular alterations, they are an ideal model for developing new therapies,” Prof Blay concluded and he added: “The more we understand about the molecular basis of these diseases, the easier it will be to develop focused therapies. The knowledge we derive from this work could also advance the development of targeted therapies more widely in cancer.”

"More than 400 experts attended the conference, where they heard about developments in surgery, advances in molecular classification of sarcomas and the shift toward personalised medicine," said co-chair Prof Paolo Casali, ESMO Board member. He pointed out that “novel treatments are now emerging for a large number of sarcoma types” and said: “The molecular mutations that underlie many sarcomas are relatively simple, making them ideal candidates for developing targeted therapies that directly address the molecular basis of the disease.”

Last update: 12 Mar 2012

This site uses cookies. Some of these cookies are essential, while others help us improve your experience by providing insights into how the site is being used.

For more detailed information on the cookies we use, please check our Privacy Policy.

Customise settings
  • Necessary cookies enable core functionality. The website cannot function properly without these cookies, and you can only disable them by changing your browser preferences.