Management of Orphan Symptoms: ESMO Clinical Practice Guidelines for diagnosis and treatment
Published in 2020 – ESMO Open (2020)
Authors: D. Santini, G. Armento, R. Giusti, M. Ferrara, C. Moro, F. Fulfaro, P. Bossi, F. Arena & C.I. Ripamonti, on behalf of the ESMO Guidelines Committee
This Clinical Practice Guideline provides key recommendations on the management of orphan symptoms. Among the most frequent orphan symptoms in patients with cancer that are related to the tumour or the antitumour treatment are muscle cramps, myoclonus, taste alterations, xerostomia, cough, hiccup, rectal tenesmus and restless legs syndrome. Authorship includes a multidisciplinary group of experts from different institutions. Key treatment recommendations are provided including levels of evidence and grades of recommendation where applicable.