Training Experience Required
The Translational Research Fellow will be exposed to a full range of translational research techniques utilising primary tissue to investigate biomarkers in ovarian cancer. Specifically, the Fellow will learn about DNA and RNA sequencing from primary material, bioinformatics and biomarker evaluation, primary cell and organoid culture. The Fellow will not be expected to undertake routine clinical work, but will be welcome to attend clinics and multidisciplinary team meetings to discuss patient management.
General description of the hospital
Imperial College through its partner hospital, Imperial Healthcare NHS Trust provides all secondary and tertiary for North West London, a population of 2 million people and hosts the regional cancer centre. In gynaecological cancer, Imperial College is one of the largest referral centres in the UK, with 7 gynaecologicla oncologists, three medical oncologists and 2 radiation oncologists solely dedicated to gynaecological malignancies. We run a comprehensive set of clinical trials, with over 150 active trials in cancer at any one time. Imperial College is regularly one of the top recruiters to NCRI portfolio clinical trials in the UK.
The translational fellow with be hosted in the Ovarian Cancer Action Research Centre, the UK's first research centre dedicated to the ovarian cancer. The Centre is housed within the Division of Cancer and Department of Surgery and Cancer in the Faculty of Medicine. The Division of Cancer hosts 25 group leaders with over 200 staff and students in total. In addition to ovarian cancer, the Division has particular expertise in breast and prostate cancers as well as cancer imaging and epigenetics, adaptation and evolution.
Within the Division of Cancer, there are two separate laboratory facilities fully equipped to support basic and translational research. The genomics facility and flow cytometry facilities are co-located on the Hammersmith Campus of Imperial College along with the National Phenome Centre, with world-class mass spectrometry facilities. Clinically, all gynaecological cancer treatment takes place at Hammersmith Hospital campus of Imperial College, including surgery, chemotherapy and radiotherapy. There is a dedicated clinical trials unit for co-ordinating clinical trials and a phase I clinical research unit also.