After graduating Medical School (2008) Myriam Chalabi did her residency in internal medicine/medical oncology. In 2016 she became staff member at the Netherlands Cancer Institute in Amsterdam as a Gastrointestinal Oncologist and clinician scientist. In 2022 she was named one of the 11 early career researchers to watch by Nature Medicine.

She is the lead investigator (PI) of several neoadjuvant immunotherapy trials in gastrointestinal cancers, including the globally renowned NICHE study, in which patients with colon cancers were found to have impressive responses after a short duration of neoadjuvant immunotherapy. Her research focuses on early innovative combination immunotherapy trials with a strong focus on translational research to better understand the drivers of response in these tumors and find novel immunotherapy combinations. Her main goal is to improve immunotherapy for patients with gastrointestinal cancers.