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Results from the first prospective study showing that patients with HER2-amplified metastatic colorectal cancer identified by ctDNA genotyping benefit from dual-HER2 blockade similarly to patients identified by conventional tissue analysis
It is intended for the treatment of patients with advanced NSCLC with KRAS G12C mutation who have progressed after at least one prior line of systemic therapy
Evidence for efficacy is based on the results from the KEYNOTE-564 study
Generating high-quality evidence from registry-based studies
Evidence for efficacy is based on the results from the ASCEMBL and CABL001X2101 studies
It is indicated for treatment of adult patients with advanced NSCLC with activating EGFR Exon 20 insertion mutations, after failure of platinum-based therapy
PET may have utility in predicting long term benefit and help guide discontinuation of therapy
Multigene panel testing may be appropriate for women with invasive lobular carcinoma and to identify women at risk
Evaluation and referral of patients with cancer based on cure probability could increase safety and overall population-level benefit of transplantation
It is indicated for the treatment of adult patients with unresectable or metastatic TNBC who have received two or more prior systemic therapies
Evidence for efficacy is based on the results from the IMpower010 study
It is indicated in patients who have received at least one prior therapy, or in first-line treatment for patients unsuitable for chemo-immunotherapy
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