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4
ESMO-MCBS v1.1
Scorecard version: 1

Indication details

Tumour Type
Thoracic Malignancies
Tumour Sub-type
Non-small-cell Lung Cancer
Tumour stage
Metastatic
Combined Agent(s)
Chemotherapy
Control Arm
Chemotherapy
Treatment Setting
1st line treatment stage IV NSCLC ECOG<2

Primary Outcome(s)

Primary Outcome(s)
QoL
Form(s)
Form 2c

Outcome Data

OS Control
8.9 months
OS Gain
2.7 months
OS HR
HR for death in control arm 1.7 (1.14-2.54)
QoL Comment
Improved

Final Score (after adjustments)

Preliminary non-curative score
4
Final non-curative Score
4

DFS, disease-free survival; DoR, duration of response; EFS, event-free survival; HR, hazard ratio; ORR, overall response rate; OS, overall survival; pCR, pathologic complete response/remission; PFS, progression-free survival; QoL, quality of life; RFS, relapse-free survival; RR, response rate

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