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Scorecard version: 1

Indication details

Tumour Type
Thoracic Malignancies
Tumour Sub-type
Non-small-cell Lung Cancer
Tumour stage
Combined Agent(s)
Control Arm
Cisplatin + gemcitabine
Treatment Setting
1st line stage III or IV (non-squamous)

Primary Outcome(s)

Primary Outcome(s)
OS (non-inferiority)
Form 2c

Outcome Data

OS Control
10.4 months
OS Gain
1.4 months
0.81 (0.70-0.94)
Toxicity Comment
Less grade 3+ toxicity: neutropenia anaemia thrombocytopenia

Final Score (after adjustments)

Preliminary non-curative score
Final non-curative Score

ChT; chemotherapy; DFS, disease-free survival; DoR, duration of response; EFS, event-free survival; FFS, failure-free survival; HR, hazard ratio; iDFS, invasive disease-free survival; ITT, intention to treat; MFS, metastasis-free survival; ORR, overall response rate; OS, overall survival; pCR, pathologic complete response/remission; PE, point estimate; PFS, progression-free survival; QoL, quality of life; RFS, relapse-free survival; RR, response rate; SD, stable disease; SSA, somatostatin analogue; SSTR, somatostatin receptor; TKI, tyrosine kinase inhibitor, TTP, time to progression

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