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3
ESMO-MCBS v1.1
Scorecard version: 1

Indication details

Tumour Type
Gynaecological Malignancies
Tumour Sub-type
Ovarian Cancer
Tumour stage
Metastatic
Combined Agent(s)
Gemcitabine + carboplatin
Control Arm
Gemcitabine + carboplatin
Treatment Setting
Recurrent platinum-sensitive ovarian cancer
Trial Name
OCEANS

Primary Outcome(s)

Primary Outcome(s)
PFS (crossover allowed)
Form(s)
Form 2b

Outcome Data

PFS Control
8.4 months
PFS Gain
4 months
PFS HR
0.48 (0.39-0.61)
OS HR
NS

Final Score (after adjustments)

Preliminary non-curative score
3
Final non-curative Score
3

DFS, disease-free survival; DoR, duration of response; EFS, event-free survival; HR, hazard ratio; ORR, overall response rate; OS, overall survival; pCR, pathologic complete response/remission; PFS, progression-free survival; QoL, quality of life; RFS, relapse-free survival; RR, response rate

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