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Epirubicin, 5-FU, Cisplatin

A
ESMO-MCBS v1.1
Scorecard version: 1

Indication details

Tumour Type
Gastrointestinal Cancers
Tumour Sub-type
Gastric or gastro-oesophageal junction adenocarcinoma
Tumour stage
Early
Control Arm
Surgery
Treatment Setting
Peri-operative resectable gastric or gastroesophageal junction adenocarcinoma
Trial Name
MAGIC

Primary Outcome(s)

Primary Outcome(s)
OS
Evaluated Outcome
OS
Form(s)
Form 1

Outcome Data

OS Control
5-year survival 23%
OS Gain
13%
OS HR
0.75 (0.60-0.93)

Final Score (after adjustments)

Final curative score
A
Issue date
11.12.2018
Last update
08.02.2022

ChT; chemotherapy; DFS, disease-free survival; DoR, duration of response; EFS, event-free survival; FFS, failure-free survival; HR, hazard ratio; iDFS, invasive disease-free survival; ITT, intention to treat; MFS, metastasis-free survival; ORR, overall response rate; OS, overall survival; pCR, pathologic complete response/remission; PE, point estimate; PFS, progression-free survival; QoL, quality of life; RFS, relapse-free survival; RR, response rate; SD, stable disease; SSA, somatostatin analogue; SSTR, somatostatin receptor; TKI, tyrosine kinase inhibitor, TTP, time to progression

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