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Will Recent Major Trials With CDK Inhibitors Be Practice Changing In Early Breast Cancer?

ESMO Webinars 1000x250 Recorded Live
Date
01 Oct 2020

Speakers

Programme

Time

Title

Speaker

5

Welcome and Introduction

Giuseppe Curigliano, University of Milano, Istituto Europeo di Oncologia, Milan, Italy

10

Risk Stratification in ER-positive/HER2-negative Early Breast Cancer: Pathological, Clinical and Genomic Risk

Lajos Pusztai, Yale Cancer Center, Yale School of Medicine, New Haven, CT, US

15

The Impact of CDK 4-6 Inhibitors in the Adjuvant Treatment of ER-positive/HER2-negative High Risk Breast Cancer

Hope Rugo, Division of Hematology and Oncology, University of California San Francisco (UCSF) Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, US

20

Omission of Chemotherapy in the Adjuvant Setting: Optimising Treatment by Risk Stratification

Giuseppe Curigliano, University of Milano, Istituto Europeo di Oncologia, Milan, Italy

25

What Have We Learned From Neoadjuvant CDK4/6 Inhibitor Trials and What Will We Plan for the Future in eBC?

Sibylle Loibl, GBG Forschungs GmbH, Academic Research Organisation (ARO), Neu-Isenburg, Germany

30

Q&A

35

Closing Remarks

Giuseppe Curigliano, University of Milano, Istituto Europeo di Oncologia, Milan, Italy

Learning objectives

  • Understand the impact of CDK 4-6 inhibitors in the adjuvant therapy of breast cancer
  • Learn how to perform a risk assessment in ER-positive/HER2-negative early breast cancer and how to define risk stratification
  • Redefine treatment selection and prioritisation in the adjuvant setting
  • Contextualise the results of the neoadjuvant trials with CDK 4-6 inhibitors in early breast cancer

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