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ESMO-MCBS Scorecards

ESMO MCBS  1000x150

The searchable portal provides a centralised location of cancer medicines that have been scored and published by ESMO.

The ESMO-MCBS Scorecards

The ESMO-MCBS Scorecards allows you to filter either by Agent, Tumour or Score giving priority to different criteria such as Agent and Tumour Type and Tumour sub-type and Tumour sub-group in the Curative or Non-curative setting. This content will be updated regularly and communicated to ESMO Members.

Tested Agent(s) Combined Agent(s) Control Arm Treatment Setting Tumour Type Tumour Sub-type Tumour Sub-group Tumour Stage Score Ref. Scorecard
Bevacizumab Paclitaxel Paclitaxel 1st line metastatic (no crossover) Breast Cancer Breast Cancer - Metastatic
2
Everolimus Exemestane Exemestane + placebo Metastatic after failure of aromatose inhibitor (with PFS> 6 months) (no crossover) Breast Cancer Breast Cancer HR+ Metastatic
2
Eribulin - Treatment of physician's choice 3rd line metastatic after anthracycline and taxane Breast Cancer Breast Cancer - Metastatic
2
Eribulin - Treatment of physician's choice 3rd line metastatic after anthracycline and taxane in HER2 negative patients Breast Cancer Breast Cancer HER2- Metastatic
1
Panitumumab FOLFOX4 (5-fluorouracil, leucovorin, and oxaliplatin) FOLFOX4 (5-fluorouracil, leucovorin, and oxaliplatin) 1st line metastatic colorectal cancer (post hoc KRAS, NRAS BRAF WT) Gastrointestinal Cancers Colon and Rectal Cancer - Metastatic
4
Panitumumab mFOLFOX6 (oxaliplatin, folinic acid, 5-fluorouracil) Bevacizumab + mFOLFOX6 (oxaliplatin, folinic acid, 5-fluorouracil) (Phase II study with unbalanced crossover) 1st line treatment Gastrointestinal Cancers Colon and Rectal Cancer RAS/BRAF-WT Metastatic
3
Cetuximab FOLFIRI (folinic acid, 5-fluorouracil, irinotecan) FOLFIRI (folinic acid, 5-fluorouracil, irinotecan) 1st line metastatic (post hoc KRAS, NRAS WT) Gastrointestinal Cancers Colon and Rectal Cancer RAS-WT Metastatic
4
Cetuximab - Best supportive care Refractory metastatic KRAS-WT Gastrointestinal Cancers Colon and Rectal Cancer KRAS-WT Metastatic
4
Bevacizumab IFL (irinotecan, leucovorin, fluorouracil) IFL (irinotecan, leucovorin, fluorouracil) + placebo 1st line treatment Gastrointestinal Cancers Colon and Rectal Cancer - Metastatic
3
Panitumumab FOLFIRI (folinic acid, 5-fluorouracil, irinotecan) FOLFIRI (folinic acid, 5-fluorouracil, irinotecan) 2nd line treatment Gastrointestinal Cancers Colon and Rectal Cancer RAS-WT Metastatic
3

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