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Translational Research Fellowship: Awardees & Reports

2018 Fellowships 

The Immune Microenvironment of a Murine Model of Clear Cell Ovarian Cancer

Fellow: Michael-John Devlin
Home institute: University College Londo Hospital, London, United Kingdom
Host institute: Institute, Queen Mary University of London, London, United Kingdom
Sponsor: Roche

Role of BDCA3high dendritic cells and type III interferon in anti-tumor immune responses

Fellow: Elisa Gobbini
Home institute: Azienda Ospedaliera Universitaria San Luigi Gonzaga, Orbassano, Italy
Host institute: Léon Bérard research center, Lyon, France
Sponsor: BMS

Illuminating the genomic landscape of hypoxia-driven early metastatic prostate cancer

Fellow: Christoph Oing
Home institute: University Medical Center Hamburg-Eppendorf, Germany
Host institute: Manchester Cancer Research Centre, Manchester, United Kingdom
Sponsor: Roche

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Development of “living organoid biobank” derived from colorectal cancer patients. Towards a personalized medicine in cancer

Fellow: Federica Papaccio
Home institute: Università degli Studi della Campania Luigi Vanvitelli, Napoli, Italy
Host institute: INCLIVA Biomedical Research Institute, Department of Medical Oncology, Hospital Clinico Universitario de Valencia
Sponsor: Amgen

2017 Fellowships

Liquid biopsy by apheresis


Fellow: Angelika Bezan (Medical University of Graz, Austria)
Home institute: Medical University of Graz, Austria
Host institute: Institute of Cancer Research, The Royal Marsden, Sutton, United Kingdom
Sponsor: Roche

An integrative bedside to bench approach for discovery and validation of new biomarkers of resistance in metastatic Colorectal Cancer (mCRC) by liquid biopsy and development of preclinical cancer models.


Fellow: Giulia Martini (Università degli Studi della Campania Luigi Vanvitelli, Naples, Italy)
Home institute: Università degli Studi della Campania Luigi Vanvitelli, Naples, Italy
Host institute: Vall d'Hebron Institute of Oncology, Barcelona, Spain
Sponsor: Amgen

Exploiting the DNA-damage response upon PARP inhibition in homologous recombination deficient tumors to maximize the activity of anti-PD-L1 therapy


Fellow: Bernadetta Pellegrino (Azienda Ospedaliera di Parma, Italy)
Home institute: Azienda Ospedaliera di Parma, Italy
Host institute: Vall d'Hebron Institute of Oncology, Barcelona, Spain
Sponsor: Roche

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2016 Fellowships

Next-generation expression analysis (NanoString) to develop prognostic and predictive gene signatures for patients with locally advanced rectal cancer treated with neoadjuvant chemoradiotherapy


Fellow: Annalisa Milano
Home institute: St. Andrea Hospital, Medical and Surgical Sciences and Translational Medicine, Rome, Italy
Host institute: Agostino Gemelli Hospital, Rome, Italy
Sponsor: Roche

Different expression of CXCR4 on CTCs from NET patients with or without skeletal metastases


Fellow: Francesca Maria Rizzo
Home institute: Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari, Department of Biomedical Sciences and Human Oncology, Bari, Italy
Host institute: UCL Cancer Institute – Department of Oncology, London, United Kingdom
Sponsor: Roche

Clear Cell Renal Cell Carcinoma: development of novel treatment strategies targeting cancer stem cells and identification of new predictive biomarkers


Fellow: Sarah Kammerer
Home institute: Medical University Graz, Institute of Biophysics, Graz, Austria
Host institute: Max Delbrück Centrum for Molecular Medicine (MDC), Berlin, Germany
Sponsor: Amgen

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Liquid Biomarkers during Fertility Preserving Procedures in BRCA Mutated Breast Cancer Patients 


Fellow: Matteo Lambertini
Home Institute: IRCCS AOU San Martino - IST, Genova, Italy
Host institute: Jules Bordet Institute, Breast Cancer Translational Research Laboratory, Brussels, Belgium
Sponsor: Amgen

2015 Fellowships

BRAVE - Brain metastases and pancReatic metastases: A clinicopathological comparison of Various facets of the tumour hEterogeneity in renal cell carcinoma


Fellow: Lisa Derosa 
Home Institute: Azienda Ospedaliero, Universitaria S.Chiara, Pisa, Italy
Host Institute: Institut Gustave Roussy, Villejuif, France
Sponsor: Roche

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The role of blood and lymph vessels in malignant pleural mesothelioma: From biology to therapy


Fellow: Zoltan Lohinai
Home Institute: National Koranyi Institute of Pulmonology, Budapest, Hungary
Host Institute: Translational Thoracic Oncology Laboratory, Division of Thoracic Surgery, Comprehensive Cancer Center, Medical University of Vienna, Austria
Sponsor: Roche

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Targeting mutational signatures in colorectal cancer


Fellow: Blanca Navarro Rodrigo
Home Institute: INCLIVA - University of Valencia, Spain
Host Institute: University Hospital of Lausanne, Ludwig Cancer Research Center, Switzerland
Sponsor: Amgen

Evaluation of MET expression and inhibition in squamous cell carcinomas of the head and neck


Fellow: Petr Szturz
Home Institute: University Hospital Brno, Czech Republic
Host Institute: Hopital Bichat - Claude Bernand, Paris, France
Sponsor: Amgen

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Therapeutic opportunities for Squamous cell carcinoma of the lung: the Hedghog pathway and beyond


Fellow: Alberto Verlicchi
Home Institute: Ospedale Civile di Ravenna, Italy
Host Institute: Germans Trias i Pujol, Barcelona, Spain
Sponsor: Roche

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2014 Fellowships

Novel biological profiles of sensitivity and/or resistance to Abiraterone and/or Enzalutamide in patients with castration-resistant prostate cancer

Fellow: Vincenza Conteduca
Home Institute: Istituto Tumori della Romagna I.R.S.T., Meldola, Italy
Host Institute: The Institute of Cancer Research, Sutton, United Kingdom
Sponsor: Roche

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The Role of MET in Primary and Acquired Resistance in HER2 positive gastric cancer

Fellow: Valentina Gambardella
Home Institute: AOU Seconda Università degli Studi di Napoli (AOU-SUN), Napoli, Italy
Host Institute: INCLIVA Biomedical Research Institute, Department of Hematology and Medical Oncology, Hospital Clinico de Valencia, University of Valencia, Spain
Sponsor: Amgen

Assessing the clinical application of circulating tumour cells in non-small cell lung cancer using therapeutic apheresis

Fellow: Colin Lindsay
Home Institute: Beatson West of Scotland Cancer Centre Gartnavel General Hospital, Glasgow, United Kingdom
Host Institute: Institut de Cancérologie Gustave Roussy, Villejuif, France
Sponsor: Roche

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Phsophorylated-STAT3 and trastuzumab resistance

Fellow: Amir Sonnenblick
Home Institute: The Hebrew University of Jerusalem- Hadassah Medical Center, Jerusalem, Israel
Host Institute: Institut Jules Bordet, Brussels, Belgium
Sponsor: Roche

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2013 Fellowships

Circulating Nucleic Acids as predictive biomarkers in Advanced Cancer Patients

Fellow: Antoine Hollebecque
Home Institute: Institut Gustave Roussy, Department of Medicine SITEP, Villejuif, France
Host Institute: Paterson Institute for Cancer Research, The University of Manchester, United Kingdom
Sponsor: Roche

 FGFR2 in gastroesophageal cancer: prognosis, prediction and the effects of therapeutic intervention

Fellow: Noelia Tarazona Llavero
Home Institute: Hospital Clinico Universitario de Valencia, Department Haematology and Medical Oncology, Valencia, Spain
Host Institute: The Royal Marsden NHS Foundation Trust, London, United Kingdom
Sponsor: Roche

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Characterization and potential clinical implications of the replication pathway in lung cancer

Fellow: Daniela Morales-Espinosa
Home Institute: Instituto Nacional de Cancerología, Department: Clinical and Basic Research Sub-direction , Mexico City, Mexico
Host Institute: Catalan Institute of Oncology, Badalona, Barcelona, Spain
Sponsor: Roche

Prevention of Brain Metastasis of Non-Squamous Non-Small Cell Lung Cancer By Antiangiogenic Therapy In Mice

Fellow: Aysegül Ilhan-Mutlu
Home Institute: Vienna General Hospital (AKH) - Medical University of Vienna, Department of Oncology, Vienna, Austria
Host Institute: University Clinic Heidelberg/Germany, German Cancer Research Centre, Heidelberg, Germany
Sponsor: Amgen

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2012 Fellowships

Prognostic and predictive role of Ki67 determined on metastatic tissue of patients with advanced breast cancer

Fellow: Claudette Falato    
Home Institute: National Cancer Institute, Naples, Italy
Host institute: Karolinska University Hospital, Stockholm, Sweden
Sponsor: Roche

Metabolomic and pharmacological patterns of resistance to the tyrosine kinase inhibitor sunitinib in patients with advanced renal-cell cancer

Fellow: Jennifer Gibbons Marsico
Home Institute: Instituto Nacional del Cancer (INCA), Montevideo, Uruguay
Host institute: Kantonsspital St Gallen, Switzerland
Sponsor: Roche

Feasibility evaluation of proliferation and nucleoside transport using FLT PET imaging in advanced pancreatic cancer patients

Fellow: Angela Lamarca
Home Institute: Hospital Universitario La Paz, Madrid, Spain
Host institute: The Christie NHS Foundation Trust, Manchester, UK
Sponsor: Amgen

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Characterisation of individual foci of multicentric/multifocal breast cancer

Fellow: Elisabetta Pietri
Home institute: Istituto Tumori della Romagna I.R.S.T. , Meldola, Italy
Host institute: Institut Jules Bordet - Breast Cancer Translational Research Laboratory, Brussels, Belgium 
Sponsor: Amgen

Identification of multiple synthetic lethal interactions with the BRAF oncogene in colorectal cancer

Fellow: Loredana Vecchione
Home institute: Katholieke Universities Leuven - Gasthuisberg University Hospital, Leuven, Belgium
Host institute: Department of Molecular Carcinogenesis B7 - NKI - Antoni van Leeuwenhoek Ziekenhuis - Prof Rene Bernards, Amsterdam, The Netherlands
Sponsor: Roche

2011 Fellowships

Identification and validation of targeted Therapeutics in triple negative breast cancer (Translational Research within Neobig programme)

FellowDaniela Kolarevic
Home institute: Institute for Oncology and Radiology of Serbia, Belgrade, Serbia
Host institute: Breakthrough Breast Cancer Research Unit, Guy's and St. Thomas Hospital, London, UK
Sponsor: Roche

Investigation of DNA repair deficiencies in Non Small Cell Lung Cancer and therapeutic applications using synthetic lethality.

Fellow: Sophie Postel-Vinay
Home institute: Institut Gustave Roussy, Paris, France
Host institute: The Institute of Cancer Research, London, UK
Sponsor: Roche

2010 Fellowships

Circulating tumour cells in metastatic breast cancer: it is time to detect and genotyping

Fellow: Leticia De Mattos-Arruda
Home institute: Santa Casa de Misericórdia de Belo Horizonte, Faculdade de Ciências Médicas de Minas Gerais, Belo Horizonte, MG, Brazil
Host institute: Vall d´Hebron University Hospital, Barcelona, Spain
Sponsor: Amgen

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Genomic Profiling of Breast Cancer diagnosed during pregnancy

Hatem Azim

Fellow: Hatem Azim
Home institute: National Cancer Institute, Cairo Oncology Centre, Mohandeseen, Egypt
Host institute: Jules Bordet Institute, Brussels, Belgium 
Sponsor: Roche

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Molecular characterisation of the stromal microenvironment in pancreatic adenocarcinoma and its role in tumour progression and prognosis

Fellow: Konstantinos-Vellios Kamposioras
Home institute: University Hospital of Larissa, Greece
Host institute: St. James Institute of Oncology Level 4, Bexley Wing, St. James University Hospital, Leeds, UK
Sponsor: Roche

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Molecular and genetic analysis of stromal fibroblasts in prostate cancer

Fellow: Michalis Karamouzis
Home institute: Medical School, University of Athens, Greece
Host institute: Department of Biological Chemistry, Medical School, University of Athens, Greece
Sponsor: Amgen

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Identification of novel molecular targets and biological agents for the chemotherapy of malignant Pleural Mesothelioma

Fellow: Giulia Pasello
Home institute: Second Medical Oncology Unit, Instituto Oncologico Veneto, Padova Italy
Host institute: Department of Oncological and Surgical Sciences, Oncology Section, Istituto Oncologico Veneto, Padova, Italy
Sponsor: Roche

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Exploring the tumour microenvironment with focus on Placental growth factor and colorectal cancer

Fellow: Karin Tamas
Home institute: Szent Laszlo Teaching Hospital, Budapest, Hungary
Host institute: University Medical Center Groningen, The Netherlands
Sponsor: Roche

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Use of MEK inhibitors to overcome primary and acquired resistance to anti-EGFR therapies

Fellow: Teresa Troiani
Home institute: Oncologia Medica, Seconda Università Degli Studi di Napoli, Dipartimento di Internistica Clinica e Sperimentale "F. Magrassie E Lanzara", Naples, Italy
Host institute: Oncologia Medica, Seconda Università Degli Studi di Napoli, Dipartimento di Internistica Clinica e Sperimentale "F. Magrassie E Lanzara", Naples, Italy
Sponsor: Amgen

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