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Clinical Fellow in Experimental Cancer Medicine/Oncology Drug Development

Publication date: 13 January 2022


The Christie NHS Foundation Trust
Wilmslow Road
M20 4BX
United Kingdom 


Job Title

Clinical Fellow in Experimental Cancer Medicine/Oncology Drug Development

Job Description

Senior Clinical Research Fellow/ Clinical Research Fellow, Experimental Cancer Medicine Team (ECMT). Appointment level dependent on experience.

The role offers an exciting opportunity to increase research capacity & deliver innovative early phase research in compliance with Good Clinical Practice & Trust policy. The post holder, with consultant oversight, will be responsible for seeing new referrals, follow-ups & for managing the patient throughout all aspects of their trial experience.

This is a 10 session non-training speciality registrar level role. The position is suitable for individuals in the second half/upon completion of their specialist training who wish to gain further experience in experimental medicine & Phase I trials, including first-in-human trials, clinical pharmacology trials & translational research. The post holder will work with experimental medicine consultants, research nurses, clinical trials coordinators, translational research facilitators, secretarial support, rotating clinical fellows & specialty trainees. The team is supported by medical & clinical oncology colleagues in all major tumour types.

Salary will be on the NHS scale in line with appropriate clinical experience. Interested candidates are encouraged to discuss this ahead of any application.

Main duties of the job
  • The post holder will be involved in managing all aspects of trial patients (both in outpatient & in-patients setting), across a diverse range of solid tumours, through new patient consultation, consent & screening patients & reviewing patients at follow-up appointments.
  • The post holder will attend Safety Review Committee meetings (usually remotely) to discuss trial patients. This will involve close liaison with Principal Investigators, referring consultant body across the Trust & other team members. The appointee will interface with external stakeholders such as CROs & pharmaceutical sponsors.
  • The appointee will undertake the administrative duties associated with the care of their patients. The appointee will be encouraged to be involved in the development & planning of new studies.
  • The Fellow will maintain a level of continuing professional development. There is the potential to present research work & the post holder will be expected to be involved in writing papers & reviews. The post holder will also be required to undergo an annual appraisal.
  • The Fellow will be expected to contribute to both undergraduate & postgraduate teaching, and aspects of clinical governance & audit.
About us

The Christie is one of the largest Cancer Centre's in Europe & a designated teaching hospital of the University of Manchester. It is a CRUK designated major cancer research centre: combined with the Cancer Research UK Manchester Institute (MI) & the University of Manchester comprises the Manchester Cancer Research Centre.

Facilities include inpatient beds, outpatient suites, trials pharmacy, laboratory & an administrative floor. The close links with the Cancer Research UK MI provide GCLP compliant laboratories.

The remit of the ECMT is to undertake cutting edge research in developing new therapeutics & conducting translational cancer research. Phase I trials are an important first step in the drug development process & are not only designed to test the safety & tolerability of novel agents but interrogate new drug formulations, combinations, pharmacokinetics & pharmacodynamics.

The post holder will be based within ECMT, providing medical support to the consultants by primarily acting as co-investigator on Phase I clinical trials. The post holder, with consultant oversight, will be responsible for seeing new referrals, follow-ups & for managing the patient throughout all aspects of their trial experience. They will join a highly motivated & empowered workforce to increase research capacity & deliver innovative early phase research in compliance with Good Clinical Practice, Trust policy & other relevant requirements.

Educational/ Qualifications
  • Completion of core medical Training or acute care common Stem programme (or equivalent)
  • CCT in Medical Oncology or equivalent
  • Good Clinical Practice
  • Advanced Life Support
  • Higher degree in cancer research
  • MRCP or equivalent
Professional Qualifications
  • GMC registration - Applications will be accepted from oversees candidates eligible for GMC registration
Research / Publications
  • Evidence of productive ethical research relevant to oncology
  • Recent publications in peer-reviewed journals
  • Conference presentations
  • Experience in general oncology and internal medicine
  • Research/Trials experience
  • Experience in managing critically ill patients
Job Specific Experience
  • Evidence of clinical leadership skills
  • Phase I trials experience
Management / Audit
  • Experience of developing, supervising and delivering audit projects
  • Experience in teaching undergraduates
  • Experience in teaching postgraduates
  • Teaching Qualification

How to apply

Contact person: Donna Graham 
Email: donna.graham8@nhs.net
Phone: 00441619182379

Application deadline

Deadline for application is 01 February 2022.

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Individuals applying for the position above should make direct contact with the institution making the offer and are responsible to verify the validity of the offer. The European Society for Medical Oncology will not accept responsibility for any error, omission or inaccuracy in any job advertising materials on this section of the website.

Submissions from individuals seeking jobs/positions will not be accepted.

Job openings at the European Society for Medical Oncology’s headquarters are available on Careers at ESMO page and on LinkedIn.

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