Publication date: 22 December 2022
University of Geneva / University Hospitals of Geneva
Rue Michel-Servet 1
The Faculty of Medicine of the University of Geneva benefits from an enriching multicultural dynamic to which it contributes through its influence within the framework of the mandates it has given itself: teaching, research and its partnership with the University Hospitals of Geneva (HUG).
A clinical and research paediatrician in paediatric oncology and haematology (80% research, 20% clinical)
In order to strengthen its dynamic team, the Department of Pediatrics, Gynecology and Obstetrics of the Faculty of Medicine of the University of Geneva is looking for a clinical and research paediatrician in paediatric oncology and haematology (80% research, 20% clinical).
The CANSEARCH research platform in paediatric oncology and haematology has been working for many years in the field of pharmacogenetics/genomics of paediatric cancers and stem cell transplantation.
Our research platform has access to the research faculty of the University of Geneva as well as to the services of the Campus Biotech, state-of-the-art bioinformatics resources, cell culture facilities and sophisticated experimental platforms for functional validation.
The selected candidate will perform 80% of the research by conducting integrative analyses of genetic or genomic data to better understand the utility of genetic markers (pharmacogenetics), in particular, to predict toxicities related to cancer chemotherapies used in the context of paediatric haematopoietic stem cell transplantation, and those encountered in the long term in paediatric cancer survivors.
He/she will participate in complex translational research projects, contribute to technical reports and papers for publication (scientific articles).
The paediatric oncologist/haematologist will carry out 20% of his/her activity in the clinic, within the Paediatric Oncology and Haematology Unit (UOHP) of the HUG. This very dynamic unit treats all types of oncological or haematological diseases, and has an activity of stem cell transplantation, immunotherapy and CAR T cells.
The general nature of the work includes, but is not limited to, the following:
- Analysis and development of the pharmacogenetics and pharmacokinetics programme in childhood cancer.
- Supervision of selected clinical studies, with the possibility of potentially becoming co-chair of some of them, presentation at national and international conferences.
- Development and fine-tuning of certain cell culture techniques and analysis of sensitivity to different chemotherapies (Treosulfan, Busulfan, etc.), in partnership with the Platform's biologists.
- Analysis of NGS (next generation sequencing) data from large patient cohorts using existing public databases (e.g. TARGET), in partnership with the Platform's bioinformatician.
- Organisation and coordination of information sharing regarding NGS data between the Platform bioinformatician and the statisticians.
- Clinical activities within the UOHP including participation in the on-call rotation.
Required qualifications and skills:
- Qualification as a paediatrician with a specialisation in paediatric oncology and haematology or in the process of obtaining it. This title must allow the practice of medicine in Switzerland.
- Excellent knowledge of pharmacology, genetics.
- Experience in processing data from pharmacogenomic studies.
- Good knowledge of molecular biology with expertise in next generation sequencing analysis.
- Working knowledge of cell culture and molecular biology experiments.
- Experience in statistical methodology and knowledge in bioinformatics.
- Ability to work independently and in a team.
- Motivation and leadership skills.
- Publication of at least 5 scientific papers in peer review journals.
- Fluency in written and spoken French and English.
How to apply
If you correspond to the above description, we would be very pleased to receive your application (covering letter, CV, certificates, diplomas, letters of reference, list of publications)
Contact person: Prof. Marc Ansari
Phone: +41 79 55 33 626
For more details on research activities and publications, please visit:
Deadline for application is 31 January 2023.
As soon as possible.
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