Translational Research Fellowship: Awardees & Reports

2016 Fellowships

Next-generation expression analysis (NanoString) to develop prognostic and predictive gene signatures for patients with locally advanced rectal cancer treated with neoadjuvant chemoradiotherapy


Fellow: Annalisa Milano
Home institute: St. Andrea Hospital, Medical and Surgical Sciences and Translational Medicine, Rome, Italy
Host institute: Agostino Gemelli Hospital, Rome, Italy
Sponsor: Roche

Different expression of CXCR4 on CTCs from NET patients with or without skeletal metastases


Fellow: Francesca Maria Rizzo
Home institute: Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari, Department of Biomedical Sciences and Human Oncology, Bari, Italy
Host institute: UCL Cancer Institute – Department of Oncology, London, United Kingdom
Sponsor: Roche

Clear Cell Renal Cell Carcinoma: development of novel treatment strategies targeting cancer stem cells and identification of new predictive biomarkers


Fellow: Sarah Kammerer
Home institute: Medical University Graz, Institute of Biophysics, Graz, Austria
Host institute: Max Delbrück Centrum for Molecular Medicine (MDC), Berlin, Germany
Sponsor: Amgen

Download the report

Liquid Biomarkers during Fertility Preserving Procedures in BRCA Mutated Breast Cancer Patients 


Fellow: Matteo Lambertini
Home Institute: IRCCS AOU San Martino - IST, Genova, Italy
Host institute: Jules Bordet Institute, Breast Cancer Translational Research Laboratory, Brussels, Belgium
Sponsor: Amgen

2015 Fellowships

BRAVE - Brain metastases and pancReatic metastases: A clinicopathological comparison of Various facets of the tumour hEterogeneity in renal cell carcinoma


Fellow: Lisa Derosa
Home Institute: Azienda Ospedaliero, Universitaria S.Chiara, Pisa, Italy
Host Institute: Institut Gustave Roussy, Villejuif, France
Sponsor: Roche

The role of blood and lymph vessels in malignant pleural mesothelioma: From biology to therapy


Fellow: Zoltan Lohinai
Home Institute: National Koranyi Institute of Pulmonology, Budapest, Hungary
Host Institute: Translational Thoracic Oncology Laboratory, Division of Thoracic Surgery, Comprehensive Cancer Center, Medical University of Vienna, Austria
Sponsor: Roche

Download the report

Targeting mutational signatures in colorectal cancer


Fellow: Blanca Navarro Rodrigo
Home Institute: INCLIVA - University of Valencia, Spain
Host Institute: University Hospital of Lausanne, Ludwig Cancer Research Center, Switzerland
Sponsor: Amgen

Evaluation of MET expression and inhibition in squamous cell carcinomas of the head and neck


Fellow: Petr Szturz
Home Institute: University Hospital Brno, Czech Republic
Host Institute: Hopital Bichat - Claude Bernand, Paris, France
Sponsor: Amgen

Download the report

Therapeutic opportunities for Squamous cell carcinoma of the lung: the Hedghog pathway and beyond


Fellow: Alberto Verlicchi
Home Institute: Ospedale Civile di Ravenna, Italy
Host Institute: Germans Trias i Pujol, Barcelona, Spain
Sponsor: Roche

Download the report

2014 Fellowships

Novel biological profiles of sensitivity and/or resistance to Abiraterone and/or Enzalutamide in patients with castration-resistant prostate cancer

Vincenza Conteduca

Fellow: Vincenza Conteduca
Home Institute: Istituto Tumori della Romagna I.R.S.T., Meldola, Italy
Host Institute: The Institute of Cancer Research, Sutton, United Kingdom
Sponsor: Roche

Download the report

The Role of MET in Primary and Acquired Resistance in HER2 positive gastric cancer

Valentina Gambardella

Fellow: Valentina Gambardella
Home Institute: AOU Seconda Università degli Studi di Napoli (AOU-SUN), Napoli, Italy
Host Institute: INCLIVA Biomedical Research Institute, Department of Hematology and Medical Oncology, Hospital Clinico de Valencia, University of Valencia, Spain
Sponsor: Amgen

Assessing the clinical application of circulating tumour cells in non-small cell lung cancer using therapeutic apheresis

Colin Lindsey

Fellow: Colin Lindsay
Home Institute: Beatson West of Scotland Cancer Centre Gartnavel General Hospital, Glasgow, United Kingdom
Host Institute: Institut de Cancérologie Gustave Roussy, Villejuif, France
Sponsor: Roche

Download the report

Phsophorylated-STAT3 and trastuzumab resistance

Amir Sonnenblick

Fellow: Amir Sonnenblick
Home Institute: The Hebrew University of Jerusalem- Hadassah Medical Center, Jerusalem, Israel
Host Institute: Institut Jules Bordet, Brussels, Belgium
Sponsor: Roche

Download the report

2013 Fellowships

Circulating Nucleic Acids as predictive biomarkers in Advanced Cancer Patients

Antoine Hollebecque

Fellow: Antoine Hollebecque
Home Institute: Institut Gustave Roussy, Department of Medicine SITEP, Villejuif, France
Host Institute: Paterson Institute for Cancer Research, The University of Manchester, United Kingdom
Sponsor: Roche

 FGFR2 in gastroesophageal cancer: prognosis, prediction and the effects of therapeutic intervention

Noelia Tarazona Llavero

Fellow: Noelia Tarazona Llavero
Home Institute: Hospital Clinico Universitario de Valencia, Department Haematology and Medical Oncology, Valencia, Spain
Host Institute: The Royal Marsden NHS Foundation Trust, London, United Kingdom
Sponsor: Roche

Download the report

Characterization and potential clinical implications of the replication pathway in lung cancer

Daniela Morales Espinosa

Fellow: Daniela Morales-Espinosa
Home Institute: Instituto Nacional de Cancerología, Department: Clinical and Basic Research Sub-direction , Mexico City, Mexico
Host Institute: Catalan Institute of Oncology, Badalona, Barcelona, Spain
Sponsor: Roche

Prevention of Brain Metastasis of Non-Squamous Non-Small Cell Lung Cancer By Antiangiogenic Therapy In Mice

Aysegul Ilhan-Mutlu

Fellow: Aysegül Ilhan-Mutlu
Home Institute: Vienna General Hospital (AKH) - Medical University of Vienna, Department of Oncology, Vienna, Austria
Host Institute: University Clinic Heidelberg/Germany, German Cancer Research Centre, Heidelberg, Germany
Sponsor: Amgen

2012 Fellowships

Prognostic and predictive role of Ki67 determined on metastatic tissue of patients with advanced breast cancer

Claudette Falato

Fellow: Claudette Falato    
Home Institute: National Cancer Institute, Naples, Italy
Host institute: Karolinska University Hospital, Stockholm, Sweden
Sponsor: Roche

Metabolomic and pharmacological patterns of resistance to the tyrosine kinase inhibitor sunitinib in patients with advanced renal-cell cancer

Jennifer Gibbons Marscio

Fellow: Jennifer Gibbons Marsico
Home Institute: Instituto Nacional del Cancer (INCA), Montevideo, Uruguay
Host institute: Kantonsspital St Gallen, Switzerland
Sponsor: Roche

Feasibility evaluation of proliferation and nucleoside transport using FLT PET imaging in advanced pancreatic cancer patients

Angela Lamarca

Fellow: Angela Lamarca
Home Institute: Hospital Universitario La Paz, Madrid, Spain
Host institute: The Christie NHS Foundation Trust, Manchester, UK
Sponsor: Amgen

Download the report

Characterisation of individual foci of multicentric/multifocal breast cancer

Elisabetta Pietri

Fellow: Elisabetta Pietri
Home institute: Istituto Tumori della Romagna I.R.S.T. , Meldola, Italy
Host institute: Institut Jules Bordet - Breast Cancer Translational Research Laboratory, Brussels, Belgium
Sponsor: Amgen

Identification of multiple synthetic lethal interactions with the BRAF oncogene in colorectal cancer

Loredana Vecchione

Fellow: Loredana Vecchione
Home institute: Katholieke Universities Leuven - Gasthuisberg University Hospital, Leuven, Belgium
Host institute: Department of Molecular Carcinogenesis B7 - NKI - Antoni van Leeuwenhoek Ziekenhuis - Prof Rene Bernards, Amsterdam, The Netherlands
Sponsor: Roche

2011 Fellowships

Identification and validation of targeted Therapeutics in triple negative breast cancer (Translational Research within Neobig programme)

Daniela Kolarevic

Fellow: Daniela Kolarevic
Home institute: Institute for Oncology and Radiology of Serbia, Belgrade, Serbia
Host institute: Breakthrough Breast Cancer Research Unit, Guy's and St. Thomas Hospital, London, UK
Sponsor: Roche

Investigation of DNA repair deficiencies in Non Small Cell Lung Cancer and therapeutic applications using synthetic lethality.

Sophie Postel-Vinay

Fellow: Sophie Postel-Vinay
Home institute: Institut Gustave Roussy, Paris, France
Host institute: The Institute of Cancer Research, London, UK
Sponsor: Roche

2010 Fellowships

Circulating tumour cells in metastatic breast cancer: it is time to detect and genotyping

Leticia De Mattos Arruda

Fellow: Leticia De Mattos-Arruda
Home institute: Santa Casa de Misericórdia de Belo Horizonte, Faculdade de Ciências Médicas de Minas Gerais, Belo Horizonte, MG, Brazil
Host institute: Vall d´Hebron University Hospital, Barcelona, Spain
Sponsor: Amgen

Download the report

Genomic Profiling of Breast Cancer diagnosed during pregnancy

Hatem Azim

Fellow: Hatem Azim
Home institute: National Cancer Institute, Cairo Oncology Centre, Mohandeseen, Egypt
Host institute: Jules Bordet Institute, Brussels, Belgium
Sponsor: Roche

Download the report

Molecular characterisation of the stromal microenvironment in pancreatic adenocarcinoma and its role in tumour progression and prognosis

Konstantinos Kamposioras

Fellow: Konstantinos-Vellios Kamposioras
Home institute: University Hospital of Larissa, Greece
Host institute: St. James Institute of Oncology Level 4, Bexley Wing, St. James University Hospital, Leeds, UK
Sponsor: Roche

Download the report

Molecular and genetic analysis of stromal fibroblasts in prostate cancer

Michalis Karamouzis

Fellow: Michalis Karamouzis
Home institute: Medical School, University of Athens, Greece
Host institute: Department of Biological Chemistry, Medical School, University of Athens, Greece
Sponsor: Amgen

Download the report

Identification of novel molecular targets and biological agents for the chemotherapy of malignant Pleural Mesothelioma

Fellow: Giulia Pasello
Home institute: Second Medical Oncology Unit, Instituto Oncologico Veneto, Padova Italy
Host institute: Department of Oncological and Surgical Sciences, Oncology Section, Istituto Oncologico Veneto, Padova, Italy
Sponsor: Roche

Download the report

Exploring the tumour microenvironment with focus on Placental growth factor and colorectal cancer

Fellow: Karin Tamas
Home institute: Szent Laszlo Teaching Hospital, Budapest, Hungary
Host institute: University Medical Center Groningen, The Netherlands
Sponsor: Roche

Download the report

Use of MEK inhibitors to overcome primary and acquired resistance to anti-EGFR therapies

Fellow: Teresa Troiani
Home institute: Oncologia Medica, Seconda Università Degli Studi di Napoli, Dipartimento di Internistica Clinica e Sperimentale "F. Magrassie E Lanzara", Naples, Italy
Host institute: Oncologia Medica, Seconda Università Degli Studi di Napoli, Dipartimento di Internistica Clinica e Sperimentale "F. Magrassie E Lanzara", Naples, Italy
Sponsor: Amgen