The ESMO Clinical Practice Guidelines (CPG) are intended to provide the user with a set of recommendations for the best standards of cancer care, based on the findings of evidence-based medicine. Each CPG includes information on the incidence of the malignancy, diagnostic criteria, staging of disease and risk assessment, treatment plans and follow-up.

ESMO is pleased to release the latest enhanced and revised set of guidelines designed to help oncologists deliver an appropriate quality of care to their patients.

ESMO Clinical Practice Guidelines, May 2010: Vol. 21, Supplement No. 5

ESMO Clinical Practice Guidelines: development, implementation and dissemination

N. Pavlidis, H. Hansen, and R. Stahel

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Primary breast cancer	S. Aebi, T. Davidson, G. Gruber, M. Castiglione	FULL TEXT	PDF
Locally recurrent or metastatic breast cancer	F. Cardoso, E. Senkus-Konefka, L. Fallowfield, A. Costa, M. Castiglione	FULL TEXT	PDF
BRCA in breast cancer	J. Balmaña , O. Diey, I. Rubino, M. Castiglione	FULL TEXT	PDF

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Newly and relapsed epithelial ovarian carcinoma	N. Colombo, M. Peiretti, G. Parma, M. Lapresa, R. Mancari, S. Carinelli, C. Sessa, M. Castiglione	FULL TEXT	PDF
Non-epithelial ovarian cancer	N. Reed, D. Millan, R. Verheijen, M. Castiglione	FULL TEXT	PDF
Cervical cancer	C. Haie-Meder, P. Morice, M. Castiglione	FULL TEXT	PDF
Endometrial carcinoma	G. Plataniotis, M. Castiglione	FULL TEXT	PDF

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Esophageal cancer	M. Stahl, W. Budach, H.-J. Meyer, A. Cervantes	FULL TEXT	PDF
Gastric cancer	A. Okines, M. Verheij, W. Allum, D. Cunningham, A. Cervantes	FULL TEXT	PDF
Pancreatic cancer	C. Cascinu. M. Falconi, V. Valentini, S. Jelic	FULL TEXT	PDF
Hepatocellular carcinoma	S. Jelic, G. C. Sotiropoulos	FULL TEXT	PDF
Biliary cancer	F. Eckel, T. Brunner, S. Jelic	FULL TEXT	PDF
Primary colon cancer	R. Labianca, B. Nordlinger, G. D. Beretta, A. Brouquet, A. Cervantes	FULL TEXT	PDF
Familial colorectal cancer risk	J. Balmaña, A. Castella, A. Cervantes	FULL TEXT	PDF
Rectal cancer	B. Glimelius, L. Påhlman, A. Cervantes	FULL TEXT	PDF
Anal cancer	R. Glynne-Jones, J. M. A. Northover, A. Cervantes	FULL TEXT	PDF
Advanced colorectal cancer	E. Van Cutsem, B. Nordliner, A. Cervantes	FULL TEXT	PDF
Gastrointestinal stromal tumours	P. G. Casali, J.-Y- Blay	FULL TEXT	PDF

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Early-stage and locally advanced (non-metastatic) non small cell lung cancer	L. Crinò, W. Weder, J. van Meerbeeck, E. Felip	FULL TEXT	PDF
Metastatic non small cell lung cancer	G. D’Addario, M. Früh, M. Reck, P. Baumann, W. Klepetko, E. Felip	FULL TEXT	PDF
Small-cell lung cancer	M. Sørensen, M. Pijls-Johannesma. E. Felip	FULL TEXT	PDF
Malignant pleural mesothelioma	R. A. Stahel, W. Weder, Y. Lievens, E. Felip	FULL TEXT	PDF

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Prostate cancer	A. Horwich, C. Parker, C. Bangma, V. Kataja	FULL TEXT	PDF
Bladder cancer	J. Bellmunt, A. Orsola, X. Maldonado, V. Kataja	FULL TEXT	PDF
Renal cell cancer	B. Escudier, V. Kataja	FULL TEXT	PDF
Testicular seminoma	H.-J. Schmoll, K. Jordan, R. Huddart, M. P. Laguna, A. Horwich, K. Fizazi and V. Kataja	FULL TEXT	PDF
Testicular non-seminoma	H.-J. Schmoll, K. Jordan, R. Huddart, M. P. Laguna, A. Horwich, K. Fizazi and V. Kataja	FULL TEXT	PDF

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Multiple myeloma	J.-L. Harousseau and M. Dreyling	FULL TEXT	PDF
Acute myeloblastic leukemia in adult patients	M. Fey and M. Dreyling	FULL TEXT	PDF
Chronic lymphocytic leukemia	B. Eichhorst, M. Hallek and M. Dreyling	FULL TEXT	PDF
Chronic myeloid leukemia	M. Baccarani and M. Dreyling	FULL TEXT	PDF
Hodgkin's lymphoma	A. Engert, D. A. Eichenauer and M. Dreyling	FULL TEXT	PDF
Diffuse large B-cell non-Hodgkin's lymphoma	H. Tilly and M. Dreyling	FULL TEXT	PDF
Gastric marginal zone lymphoma of MALT type	E. Zucca and M. Dreyling	FULL TEXT	PDF
Primary cutaneous lymphoma	R. Willemze and M. Dreyling	FULL TEXT	PDF
Newly diagnosed and relapsed follicular lymphoma	M. Dreyling	FULL TEXT	PDF

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Squamous cell carcinoma of the head and neck	V. Grégoire, J.-L. Lefebvre, L. Licitra, E. Felip	FULL TEXT	PDF
Nasopharyngeal cancer	A. T. C. Chan, V. Greégroire, J.-L. Lefebvre, L. Licitra, E. Felip	FULL TEXT	PDF

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High-grade malignant glioma

R. Stupp,J.-C. Tonn, M. Brada,G. Pentheroudakis

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Melanoma	R. Dummer, A. Hauschild, M. Guggenheim, L. Jost, G. Pentheroudakis	FULL TEXT	PDF
Soft tissue sarcomas	P.G. Casali, J.-Y. Blay	FULL TEXT	PDF
Bone sarcomas	P.C.W. Hogendoorn	FULL TEXT	PDF

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Thyroid cancer	F. Pacini, M. G. Castagna, L. Brilli and G. Pentheroudakis	FULL TEXT	PDF
Neuroendocrine bronchial and thymic tumors	K. Öberg, P. Hellman, D. Kwekkeboom, S. Jelic	FULL TEXT	PDF
Neuroendocrine gastroenteropancreatic tumors	K. Öberg, G. Åkerström, G. Rindi, S. Jelic	FULL TEXT	PDF
Cancers of unknown primary site	N. Pavlidis, E. Briasoulis, G. Pentheroudakis	FULL TEXT	PDF

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Guideline update for MASCC & ESMO in the prevention of chemotherapy and radiotherapy-induced nausea and vomiting	F. Roila, J. Herrstedt, M. Aapro, R. J. Gralla, L.H. Einhorn, E. Ballatori, E. Bria, R.A. Clark-Snow, B. T. Espersen, P. Feyer, S.M. Grunberg, P.J. Hesketh, K. Jordan, M.G. Kris, E. Maranzano, A. Molassiotis, G. Morrow, I. Olver, B.L. Rapoport, C. Rittenberg, M. Saito, M. Tonato, D. Warr	FULL TEXT	PDF
Erythropoiesis-stimulating agents in the treatment of anaemia in cancer patients	D. Schrijvers, H. De Samblanx, F. Roila	FULL TEXT	PDF
Hematopoietic growth factors	J. Crawford, C. Caserta, F. Roila	FULL TEXT	PDF
Management of febrile neutropenia	J. de Naurois, I. Novitzky-Basso, M. J. Gill, F. Marti Marti, M. H. Cullen, F. Roila	FULL TEXT	PDF
Management of cancer pain	L. Jost and F. Roila	FULL TEXT	PDF
Management of oral and gastrointestinal mucositis	D. E. Peterson, R.-J. Bensadoun and F. Roila	FULL TEXT	PDF
Cancer, fertility and pregnancy	G. Pentheroudakis, R. Orecchia, H. J. Hoekstra, N. Pavlidis	FULL TEXT	PDF
Venous thromboembolism in cancer patients	M. Mandalà, A. Falanga and F. Roila	FULL TEXT	PDF
Cardiotoxicity of chemotherapeutic agents and radiotherapy-related heart disease	D. Bovelli, G. Plataniotis, F. Roila	FULL TEXT	PDF

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The ESMO Guidelines Working Group acknowledges and thanks the people who have acted as reviewers for these ESMO Clinical Practice Guidelines

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The members of the Guidelines Working Group have made the following disclosures

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Clinical Practice Guidelines are not designed to replace extensive clinical practice guidelines or review articles, but rather to describe common standards of care.

The ESMO CPG are updated annually by the ESMO Guidelines Working Group, who manages and supervises them, while the ESMO Faculty members perform reviews and provide further expert opinion.

Clinical guidelines are important for the development of oncology as a specialty and serve to achieve many important goals:

• reach and maintain a high common standard of care in medical practice for cancer patients and help clinicians to offer the best care
• disseminate knowledge by supporting the translation into many languages
• support negotiations with politicians, administrators and insurance companies regarding what level of care should be made available
• help patients to find information on the therapies they are undergoing