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ESMO Clinical Practice Guidelines
The ESMO Clinical Practice Guidelines (CPG) are intended to provide the user with a set of recommendations for the best standards of cancer care, based on the findings of evidence-based medicine. Each CPG includes information on the incidence of the malignancy, diagnostic criteria, staging of disease and risk assessment, treatment plans and follow-up.
ESMO is pleased to release the latest enhanced and revised set of guidelines designed to help oncologists deliver an appropriate quality of care to their patients.
Editorial
| New in 2011! Fourteen years of evolution of ESMO Guidelines: from the minimum recommendations to the Consensus Conference-derived guidelines |
N. Pavlidis, R. Stahel, H. Hansen, and A. Cervantes | FULL TEXT |
Breast cancer
| New in 2011! Primary breast cancer |
S. Aebi, T. Davidson, G. Gruber, F. Cardoso | FULL TEXT | |
| New in 2011! Locally recurrent or metastatic breast cancer |
F. Cardoso, L. Fallowfield, A. Costa, M. Castiglione, E. Senkus | FULL TEXT | |
| New in 2011! BRCA in breast cancer |
J. Balmana, O. Diez, I.T. Rubio, F. Cardoso | FULL TEXT |
Gynecologic tumors
| Newly and relapsed epithelial ovarian carcinoma |
N. Colombo, M. Peiretti, G. Parma, M. Lapresa, R. Mancari, S. Carinelli, C. Sessa, M. Castiglione |
FULL TEXT | |
| Non-epithelial ovarian cancer | N. Reed, D. Millan, R. Verheijen, M. Castiglione |
FULL TEXT | |
| Cervical cancer | C. Haie-Meder, P. Morice, M. Castiglione | FULL TEXT | |
| New in 2011! Endometrial cancer |
N. Colombo, E. Preti, F. Landoni, S. Carinelli, A. Colombo, C. Marini, C. Sessa |
FULL TEXT |
Gastrointestinal tumors
| Esophageal cancer | M. Stahl, W. Budach, H.-J. Meyer, A. Cervantes | FULL TEXT | |
| Gastric cancer | A. Okines, M. Verheij, W. Allum, D. Cunningham, A. Cervantes |
FULL TEXT | |
| Pancreatic cancer | C. Cascinu. M. Falconi, V. Valentini, S. Jelic |
FULL TEXT | |
| Hepatocellular carcinoma | S. Jelic, G. C. Sotiropoulos | FULL TEXT | |
| New in 2011! Biliary cancer |
F. Eckel, T. Brunner, S. Jelic | FULL TEXT | |
| Primary colon cancer | R. Labianca, B. Nordlinger, G. D. Beretta, A. Brouquet, A. Cervantes |
FULL TEXT | |
| Familial colorectal cancer risk | J. Balmaña, A. Castella, A. Cervantes | FULL TEXT | |
| Rectal cancer | B. Glimelius, L. Påhlman, A. Cervantes | FULL TEXT | |
| Anal cancer | R. Glynne-Jones, J. M. A. Northover, A. Cervantes | FULL TEXT | |
| Advanced colorectal cancer | E. Van Cutsem, B. Nordliner, A. Cervantes | FULL TEXT | |
| Gastrointestinal stromal tumours | P. G. Casali, J.-Y- Blay | FULL TEXT |
Lung cancer
| Early-stage and locally advanced (non-metastatic) non small cell lung cancer |
L. Crinò, W. Weder, J. van Meerbeeck, E. Felip |
FULL TEXT | |
| Metastatic non small cell lung cancer | G. D’Addario, M. Früh, M. Reck, P. Baumann, W. Klepetko, E. Felip |
FULL TEXT | |
| Small-cell lung cancer | M. Sørensen, M. Pijls-Johannesma. E. Felip | FULL TEXT | |
| Malignant pleural mesothelioma | R. A. Stahel, W. Weder, Y. Lievens, E. Felip | FULL TEXT |
Urogenital tumors
| Prostate cancer | A. Horwich, C. Parker, C. Bangma, V. Kataja | FULL TEXT | |
| New in 2011! Bladder cancer |
J. Bellmunt, A. Orsola, T. Wiegel, M. Guix, M. De Santis, V. Kataja |
FULL TEXT | |
| Renal cell cancer | B. Escudier, V. Kataja | FULL TEXT | |
| Testicular seminoma | H.-J. Schmoll, K. Jordan, R. Huddart, M. P. Laguna, A. Horwich, K. Fizazi and V. Kataja |
FULL TEXT | |
| Testicular non-seminoma | H.-J. Schmoll, K. Jordan, R. Huddart, M. P. Laguna, A. Horwich, K. Fizazi and V. Kataja |
FULL TEXT |
Hematologic malignancies
| Multiple myeloma | J.-L. Harousseau and M. Dreyling | FULL TEXT | |
| Acute myeloblastic leukemia in adult patients |
M. Fey and M. Dreyling | FULL TEXT | |
| New in 2011! Chronic lymphocytic leukemia |
B. Eichhorst, M. Dreyling, T. Robak. E.Montserrat, M. Hallek | FULL TEXT | |
| Chronic myeloid leukemia | M. Baccarani and M. Dreyling | FULL TEXT | |
| New in 2011! Hodgkin's lymphoma |
D.A. Eichenauer, A. Engert, M. Dreyling | FULL TEXT | |
| Diffuse large B-cell non-Hodgkin's lymphoma |
H. Tilly and M. Dreyling | FULL TEXT | |
| Gastric marginal zone lymphoma of MALT type |
E. Zucca and M. Dreyling | FULL TEXT | |
| Primary cutaneous lymphoma | R. Willemze and M. Dreyling | FULL TEXT | |
| New in 2011! Newly diagnosed and relapsed follicular lymphoma |
M. Dreyling, M. Ghielmini, R. Marcus, G. Salles, U. Vitolo | FULL TEXT |
Head and neck tumors
| Squamous cell carcinoma of the head and neck |
V. Grégoire, J.-L. Lefebvre, L. Licitra, E. Felip |
FULL TEXT | |
| Nasopharyngeal cancer | A. T. C. Chan, V. Greégroire, J.-L. Lefebvre, L. Licitra, E. Felip |
FULL TEXT |
CNS
| High-grade malignant glioma | R. Stupp,J.-C. Tonn, M. Brada,G. Pentheroudakis | FULL TEXT |
Sarcomas and melanomas
| Melanoma | R. Dummer, A. Hauschild, M. Guggenheim, L. Jost, G. Pentheroudakis |
FULL TEXT | |
| Soft tissue sarcomas | P.G. Casali, J.-Y. Blay | FULL TEXT | |
| Bone sarcomas | P.C.W. Hogendoorn | FULL TEXT |
Neuroendocrine tumors
| Thyroid cancer | F. Pacini, M. G. Castagna, L. Brilli and G. Pentheroudakis |
FULL TEXT | |
| Neuroendocrine bronchial and thymic tumors |
K. Öberg, P. Hellman, D. Kwekkeboom, S. Jelic |
FULL TEXT | |
| Neuroendocrine gastroenteropancreatic tumors |
K. Öberg, G. Åkerström, G. Rindi, S. Jelic |
FULL TEXT | |
| New in 2011! Cancers of unknown primary site |
K. Fizazi, F. A. Greco, N. Pavlidis, G. Pentheroudakis | FULL TEXT |
Supportive care
| Guideline update for MASCC & ESMO in the prevention of chemotherapy and radiotherapy-induced nausea and vomiting |
F. Roila, J. Herrstedt, M. Aapro, R. J. Gralla, L.H. Einhorn, E. Ballatori, E. Bria, R.A. Clark-Snow, B. T. Espersen, P. Feyer, S.M. Grunberg, P.J. Hesketh, K. Jordan, M.G. Kris, E. Maranzano, A. Molassiotis, G. Morrow, I. Olver, B.L. Rapoport, C. Rittenberg, M. Saito, M. Tonato, D. Warr |
FULL TEXT | |
| Erythropoiesis-stimulating agents in the treatment of anaemia in cancer patients |
D. Schrijvers, H. De Samblanx, F. Roila | FULL TEXT | |
| Hematopoietic growth factors | J. Crawford, C. Caserta, F. Roila | FULL TEXT | |
| Management of febrile neutropenia | J. de Naurois, I. Novitzky-Basso, M. J. Gill, F. Marti Marti, M. H. Cullen, F. Roila |
FULL TEXT | |
| New in 2011! Management of cancer pain |
C. I. Ripamonti, E. Bandieri, F. Roila | FULL TEXT | |
| New in 2011! Management of oral and gastrointestinal mucositis |
D. E. Peterson, R.-J. Bensadoun and F. Roila |
FULL TEXT | |
| Cancer, fertility and pregnancy | G. Pentheroudakis, R. Orecchia, H. J. Hoekstra, N. Pavlidis |
FULL TEXT | |
| New in 2011! Management of venous thromboembolism (VTE) in cancer patients |
M. Mandalà, A. Falanga and F. Roila |
FULL TEXT | |
| Cardiotoxicity of chemotherapeutic agents and radiotherapy-related heart disease |
D. Bovelli, G. Plataniotis, F. Roila | FULL TEXT |
Acknowledgements
The ESMO Guidelines Working Group acknowledges and thanks the people who have acted as reviewers for these ESMO Clinical Practice Guidelines
Guidelines Working Group Members
Disclosures
The members of the Guidelines Working Group have made the following disclosures
Clinical Practice Guidelines are not designed to replace extensive clinical practice guidelines or review articles, but rather to describe common standards of care.
The ESMO CPG are updated annually by the ESMO Guidelines Working Group, who manages and supervises them, while the ESMO Faculty members perform reviews and provide further expert opinion.
Clinical guidelines are important for the development of oncology as a specialty and serve to achieve many important goals:
- reach and maintain a high common standard of care in medical practice for cancer patients and help clinicians to offer the best care
- disseminate knowledge by supporting the translation into many languages
- support negotiations with politicians, administrators and insurance companies regarding what level of care should be made available
- help patients to find information on the therapies they are undergoing


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