ESMO Glossary in Molecular Biology of Cancer
Prepared by the Translational Research Working Group and accompanied by illustrative images, the Glossary in Molecular Biology of Cancer is available via ESMO's unique educational portal OncologyPRO
The aim of the ESMO Glossary in Molecular Biology of Cancer is to serve as an aid to practicing oncologists while they are acquiring knowledge and developing an awareness and appreciation of the molecular processes underlying the development of cancer.
In developing this Glossary, the ESMO Translational Research Working Group (TRWG) considered a review of a previous ESMO document, the Glossary in Molecular Biology of Cancer, as a priority. The first edition was produced more than a decade ago on the occasion of an ESMO educational course. The aim was to enhance the understanding of attendees in a difficult area for most clinicians. In the meantime, the field of cancer biology has become increasingly important and new complex terms and knowledge have emerged. Therefore, the members of the ESMO TRWG have revised the textual content of the previous Glossary, basically the definitions of terms ordered from A to Z.
During the revision process, the question of having more incentives from such a publication was raised, and the idea of adding images illustrative of the terms was born. Images for certain terms have been selected with permission from the respective journals where they were initially published. In addition, TRWG members wished to see incentives beyond classical reading and suggested accompanying each selected term by an image consisting of two panes, one of the structure of the gene, and the second of its network.
By producing this booklet, the ESMO TRWG wishes to help clinicians to understand the basic requirements for the common laboratory techniques used to demonstrate molecular features of malignancy when critically evaluating and interpreting research findings. The ultimate goal of the Glossary is to develop a common terminology and to enable oncology practitioners to speak the same language as basic scientists and translational researchers when analysing research findings and translating cancer biology to cancer medicine.
The Glossary is dedicated to all oncologists keen to keep abreast of the latest advances in knowledge of the molecular biology of cancer. It will be printed in a limited number of copies and is available to download from ESMO's educational portal for members: OncologyPRO. All images from the Glossary will be available in slide resources.
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