ESMO National Representative in Luxembourg
|Term||2015 – 2016|
Centre Hospitalier de Luxembourg
Rue Barble 4
Dr. Guy Berchem is a medical oncologist graduated from the Université Libre de Bruxelles (ULB) Medical School in 1990. He did his Medical Oncology training at the Brussels Institut Jules Bordet Cancer Center (Jean Klastersky and Martine Piccart) and his laboratory training as a research fellow in Lombardi Cancer Center, Georgetown University Washington DC (Mark Lippman and Ed. Gelman).
During his fellowship he contributed to the understanding of apoptotic mechanisms in hormone sensitive and hormone resistant prostate cancer and participated in studies on angiogenesis in breast cancer.
Since then he held part clinical and part laboratory research appointments, for 3 years at Institut Bordet in Prof. Arsène Burny’s lab, and in 2003 he founded the Laboratory of Experimental Cancer Research at the Luxembourg Institute of Health (LIH) which he still heads today. He also holds a clinical position as attending physician in Medical Oncology at the Centre Hospitalier in Luxembourg.
His clinical work is essentially focused on lung cancer and neuro-oncology. He has participated in many national and international studies of these diseases. The work of his lab has been focused on the better understanding of cell death and cell survival mechanisms in MM and CLL as well as on the study of NK based immuno-evasion involving hypoxia induced autophagy, and biomarker based promotion of personalized medicine in Luxembourg.
In 2014 he presented a PhD thesis entitled: « Rôle du stress hypoxique dans la régulation de la réponse immunitaire anti-tumorale des lymphocytes "Natural Killer" » at the University Paris Sud (XI), Gustave Roussy.
He co-founded the Luxembourg National Institute of Cancer (inc.lu) - where he currently serves as President - as well as the Luxembourg Society of Oncology in 2002. Since 2008 he is the Luxembourg delegate to the CAT committee at EMA in London.