Management of Febrile Neutropaenia: ESMO Clinical Practice Guidelines

Published in 2016 – Ann Oncol (2016) 27 (suppl 5): v111-v118 

Authors: J. Klastersky, J. de Naurois, K. Rolston, B. Rapoport, G. Maschmeyer, M. Aapro and J. Herrstedt

Febrile neutropaenia is the development of fever, often with other signs of infection, in a patient with neutropaenia, an abnormally low number of neutrophil granulocytes in the blood. Despite major advances in prevention and treatment, febrile neutropaenia is associated with the intensity of chemotherapy and remains one of the most frequent and serious complications of cancer chemotherapy. The updated ESMO Clinical Practice Guidelines include key recommendations for the assessment, risk assessment and management of febrile neutropaenia including patient education and local policies.

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