Anal Cancer: ESMO-ESSO-ESTRO Clinical Practice Guidelines

Published in 2014 – Ann Oncol (2014) 25 (suppl 3): iii10-iii20.

Authors: R. Glynne-Jones, P. J. Nilsson, C. Aschele, V. Goh, D. Peiffert, A. Cervantes, and D. Arnold

Squamous cell carcinoma of the anus (SCCA) is strongly associated with human papillomavirus (HPV) infection which represents the causative agent in 80%–85% of patients (usually from HPV16 or HPV18 subtypes in Europe) as is its precursor lesion anal intra-epithelial neoplasia (AIN) 3. This ESMO-ESSO-ESTRO Guideline gives information on the incidence and epidemiology, diagnosis, screening, pathology and molecular biology of the disease as well as current treatment options and follow-up.

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